{"id":31541,"date":"2025-10-06T01:05:46","date_gmt":"2025-10-05T22:05:46","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=31541"},"modified":"2025-10-06T01:05:46","modified_gmt":"2025-10-05T22:05:46","slug":"%d8%b1%d8%ad%d9%84%d8%a9-%d8%af%d9%88%d8%a7%d8%a1-%d9%88%d8%a7%d8%b9%d8%af-%d9%81%d9%8a-%d9%85%d9%83%d8%a7%d9%81%d8%ad%d8%a9-%d8%a7%d9%84%d8%b3%d9%83%d8%b1%d9%8a-%d9%88%d8%a7%d9%84%d8%b3%d9%85%d9%86","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=31541","title":{"rendered":"\u0631\u062d\u0644\u0629 \u062f\u0648\u0627\u0621 \u0648\u0627\u0639\u062f \u0641\u064a \u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0644\u0633\u0645\u0646\u0629 [\u0645\u0646 \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u0625\u0644\u0649 \u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0644\u0639\u0644\u0627\u062c] – \u0628\u0642\u0644\u0645 \u063a\u0633\u0627\u0646 \u0639\u0644\u064a \u0628\u0648\u062e\u0645\u0633\u064a\u0646"},"content":{"rendered":"

\u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a \u064a\u0634\u0643\u0644\u0627\u0646 \u0645\u0639\u064b\u0627 \u062b\u0646\u0627\u0626\u064a\u064b\u0627 \u0648\u0628\u0627\u0626\u064a\u064b\u0627 \u064a\u0647\u062f\u062f \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0639\u0627\u0644\u0645\u064a\u064b\u0627… <\/span><\/strong><\/p>\n

\u062e\u0644\u0642\u062a \u0647\u0630\u0647 \u0627\u0644\u0623\u0632\u0645\u0629 \u0633\u0648\u0642\u064b\u0627 \u0635\u062d\u064a\u0629 \u0636\u062e\u0645\u0629\u060c \u062a\u0634\u0645\u0644 \u0623\u062f\u0648\u064a\u0629 \u062e\u0641\u0636 \u0627\u0644\u0648\u0632\u0646\u060c \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u0630\u0627\u062a\u064a\u0629\u060c \u0648\u0627\u0644\u062c\u0631\u0627\u062d\u0627\u062a \u0627\u0644\u0623\u064a\u0636\u064a\u0629. \u062a\u064f\u0634\u0643\u0651\u0644 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0645\u0646\u0629 \u0639\u0628\u0626\u064b\u0627 \u0627\u0642\u062a\u0635\u0627\u062f\u064a\u064b\u0627 \u0645\u062a\u0632\u0627\u064a\u062f\u064b\u0627\u060c \u0625\u0630 \u062a\u062a\u0646\u0648\u0639 \u062a\u0643\u0627\u0644\u064a\u0641\u0647\u0627 \u0628\u064a\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062d\u062f\u064a\u062b\u0629 \u0645\u062b\u0644 \u0646\u0627\u0647\u0636\u0627\u062a (GLP-1)\u060c \u0648\u0627\u0644\u062c\u0631\u0627\u062d\u0627\u062a \u0645\u062b\u0644 \u062a\u0643\u0645\u064a\u0645 \u0627\u0644\u0645\u0639\u062f\u0629\u060c \u0648\u0627\u0644\u0628\u0631\u0627\u0645\u062c \u0627\u0644\u0633\u0644\u0648\u0643\u064a\u0629 \u0648\u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0631\u0642\u0645\u064a\u0629. <\/span><\/p>\n

\u062a\u062a\u0631\u0627\u0648\u062d \u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0641\u0631\u062f\u064a \u0633\u0646\u0648\u064a\u064b\u0627 \u0645\u0646 \u0645\u0626\u0627\u062a \u0625\u0644\u0649 \u0622\u0644\u0627\u0641 \u0627\u0644\u062f\u0648\u0644\u0627\u0631\u0627\u062a\u060c \u0628\u064a\u0646\u0645\u0627 \u062a\u064f\u0642\u062f\u0651\u0631 \u0627\u0644\u0623\u0639\u0628\u0627\u0621 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a\u0629 \u0644\u0644\u0633\u0645\u0646\u0629 \u0639\u0627\u0644\u0645\u064a\u064b\u0627 \u0628\u0623\u0643\u062b\u0631 \u0645\u0646 4 \u062a\u0631\u064a\u0644\u064a\u0648\u0646\u0627\u062a \u062f\u0648\u0644\u0627\u0631 \u0628\u062d\u0644\u0648\u0644 2035. \u0647\u0630\u0627 \u0627\u0644\u0639\u0628\u0621 \u064a\u0634\u0645\u0644 \u062a\u0643\u0627\u0644\u064a\u0641 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u0645\u0628\u0627\u0634\u0631\u0629\u060c \u0648\u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0625\u0646\u062a\u0627\u062c\u064a\u0629\u060c \u0648\u0632\u064a\u0627\u062f\u0629 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u0632\u0645\u0646\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0633\u0645\u0646\u0629.<\/span><\/p>\n

\"\"
\u0646\u0645\u0648 \u0642\u0648\u064a \u0648\u0633\u0631\u064a\u0639 \u0645\u062a\u0648\u0642\u0639 \u0644\u0623\u062f\u0648\u064a\u0629 \u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u0633\u0645\u0646\u0629 \u0628\u064a\u0646 \u0639\u0627\u0645\u064a 2023-2030<\/span><\/figcaption><\/figure>\n

\u0641\u064a \u062e\u0636\u0645 \u0627\u0644\u0645\u0639\u0631\u0643\u0629 \u0627\u0644\u0645\u0633\u062a\u0639\u0631\u0629 \u0636\u062f \u062c\u0627\u0626\u062d\u062a\u064a \u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a\u060c \u0634\u0647\u062f \u0627\u0644\u0639\u0642\u062f \u0627\u0644\u0645\u0627\u0636\u064a \u062b\u0648\u0631\u0629 \u063a\u064a\u0631 \u0645\u0633\u0628\u0648\u0642\u0629 \u0628\u0638\u0647\u0648\u0631 \u0641\u0626\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u062a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0627\u0644\u0634\u0628\u064a\u0647 \u0628\u0627\u0644\u062c\u0644\u0648\u0643\u0627\u062c\u0648\u0646-1 (GLP-1 RA). \u0623\u062f\u0648\u064a\u0629 \u0645\u062b\u0644 (\u0623\u0648\u0632\u0645\u0628\u064a\u0643) \u0623\u0648 (\u0645\u0648\u0646\u062c\u0627\u0631\u0648) \u063a\u064a\u0631\u062a \u0645\u0639\u0627\u064a\u064a\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0641\u0639\u0627\u0644\u064a\u062a\u0647\u0627 \u0627\u0644\u0645\u0644\u062d\u0648\u0638\u0629 \u0641\u064a \u062e\u0641\u0636 \u0633\u0643\u0631 \u0627\u0644\u062f\u0645 \u0648\u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0648\u0632\u0646.<\/span><\/p>\n

\u0648\u0644\u0643\u0646\u060c \u0638\u0644 \u0647\u0646\u0627\u0643 \u062a\u062d\u062f\u064d \u0631\u0626\u064a\u0633\u064a: \u0627\u0644\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u0627\u0644\u062d\u0642\u0646 \u0627\u0644\u064a\u0648\u0645\u064a \u0623\u0648 \u0627\u0644\u0623\u0633\u0628\u0648\u0639\u064a \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f\u060c \u0645\u0645\u0627 \u064a\u0634\u0643\u0644 \u0639\u0627\u0626\u0642\u064b\u0627 \u0644\u0628\u0639\u0636 \u0627\u0644\u0645\u0631\u0636\u0649. \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u0637\u0644\u0642\u060c \u0627\u0646\u0628\u062b\u0642\u062a \u0631\u062d\u0644\u0629 \u0627\u0644\u0628\u062d\u062b \u0639\u0646 \u062c\u064a\u0644 \u062c\u062f\u064a\u062f \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u064a\u0645\u0643\u0646 \u062a\u0646\u0627\u0648\u0644\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645\u060c \u0648\u0643\u0627\u0646 \u0623\u0648\u0631\u0641\u0648\u062c\u0644\u064a\u0628\u0631\u0648\u0646 (Orforglipron) \u0623\u062d\u062f \u0623\u0628\u0631\u0632 \u0627\u0644\u0645\u0631\u0634\u062d\u064a\u0646 \u0644\u062a\u062d\u0642\u064a\u0642 \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0629.<\/span><\/strong><\/p><\/blockquote>\n

\"\"
\u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0627\u0644\u0628\u0646\u0627\u0626\u064a \u0627\u0644\u0645\u0639\u0642\u062f \u0644\u062f\u0648\u0627\u0621 (semaglutide)<\/span><\/figcaption><\/figure>\n

\u0623\u0648\u0631\u0641\u0648\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0644\u064a\u0633 \u062f\u0648\u0627\u0621\u064b \u0641\u0645\u0648\u064a\u064b\u0627 \u0645\u0646 \u0641\u0626\u0629 \u0646\u0627\u0647\u0636\u0627\u062a (GLP-1) \u0627\u0644\u062a\u0642\u0644\u064a\u062f\u064a\u0629\u060c \u0628\u0644 \u064a\u0646\u062a\u0645\u064a \u0625\u0644\u0649 \u0641\u0626\u0629 \u0623\u0643\u062b\u0631 \u062a\u0637\u0648\u0631\u064b\u0627 \u062a\u0633\u0645\u0649 “\u0645\u0642\u0644\u062f\u0627\u062a (GLP-1) \u063a\u064a\u0631 \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u064a\u0629” (Non-peptide GLP-1 receptor agonists).<\/span><\/p>\n

\u0627\u0644\u0641\u0631\u0642 \u0627\u0644\u062c\u0648\u0647\u0631\u064a:<\/strong> \u0623\u062f\u0648\u064a\u0629 (GLP-1) \u0627\u0644\u062a\u0642\u0644\u064a\u062f\u064a\u0629 (\u0645\u062b\u0644 \u0633\u064a\u0645\u0627\u063a\u0644\u0648\u062a\u0627\u064a\u062f) \u0647\u064a \u062c\u0632\u064a\u0626\u0627\u062a \u0628\u0628\u062a\u064a\u062f\u064a\u0629\u060c \u0623\u064a \u0623\u0646\u0647\u0627 \u0633\u0644\u0627\u0633\u0644 \u0645\u0646 \u0627\u0644\u0623\u062d\u0645\u0627\u0636 \u0627\u0644\u0623\u0645\u064a\u0646\u064a\u0629 \u062a\u0634\u0628\u0647 \u0625\u0644\u0649 \u062d\u062f \u0643\u0628\u064a\u0631 \u0647\u0631\u0645\u0648\u0646 (GLP-1) \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0641\u064a \u0627\u0644\u062c\u0633\u0645. \u0628\u0633\u0628\u0628 \u0637\u0628\u064a\u0639\u062a\u0647\u0627 \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u064a\u0629\u060c \u0641\u0625\u0646\u0647\u0627 \u062a\u062a\u062d\u0637\u0645 \u0628\u0633\u0631\u0639\u0629 \u0641\u064a \u0627\u0644\u0645\u0639\u062f\u0629 \u0648\u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0625\u0630\u0627 \u0623\u062e\u0630\u062a \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645\u060c \u0645\u0645\u0627 \u064a\u0633\u062a\u0644\u0632\u0645 \u0635\u064a\u0627\u063a\u062a\u0647\u0627 \u0628\u0634\u0643\u0644 \u062e\u0627\u0635 (\u0643\u0645\u0627 \u0641\u064a \u062d\u0627\u0644\u0629 (Rybelsus)) \u0623\u0648 \u062d\u0642\u0646\u0647\u0627.<\/span><\/p>\n

\u0627\u0644\u062a\u0635\u0645\u064a\u0645 \u0627\u0644\u062b\u0648\u0631\u064a:<\/strong> \u0623\u0648\u0631\u0641\u0648\u062c\u0644\u064a\u0628\u0631\u0648\u0646\u060c \u0639\u0644\u0649 \u0627\u0644\u0646\u0642\u064a\u0636 \u0645\u0646 \u0630\u0644\u0643\u060c \u0647\u0648 \u062c\u0632\u064a\u0621 \u0635\u063a\u064a\u0631 \u063a\u064a\u0631 \u0628\u0628\u062a\u064a\u062f\u064a. \u062a\u0645 \u062a\u0635\u0645\u064a\u0645\u0647 \u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u062f\u0648\u0627\u0639 \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629 \u0644\u064a\u0631\u062a\u0628\u0637 \u0628\u0645\u0633\u062a\u0642\u0628\u0644 (GLP-1) \u0641\u064a \u0627\u0644\u0628\u0646\u0643\u0631\u064a\u0627\u0633 \u0648\u0627\u0644\u062f\u0645\u0627\u063a \u0648\u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0623\u062e\u0631\u0649 \u0648\u064a\u0646\u0634\u0637\u0647\u060c \u0645\u062d\u0627\u0643\u064a\u064b\u0627 \u0628\u0630\u0644\u0643 \u0639\u0645\u0644 \u0627\u0644\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0648\u0644\u0643\u0646 \u0628\u062f\u0648\u0646 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0628\u0631\u0648\u062a\u064a\u0646\u064b\u0627. \u0647\u0630\u0647 \u0627\u0644\u0637\u0628\u064a\u0639\u0629 “\u063a\u064a\u0631 \u0627\u0644\u0628\u0628\u062a\u064a\u062f\u064a\u0629” \u0647\u064a \u0627\u0644\u062a\u064a \u062a\u0633\u0645\u062d \u0644\u0647 \u0628\u0627\u0644\u0628\u0642\u0627\u0621 \u0645\u0633\u062a\u0642\u0631\u064b\u0627 \u0648\u0645\u0642\u0627\u0648\u0645\u064b\u0627 \u0644\u0644\u062a\u062d\u0644\u0644 \u0628\u0648\u0627\u0633\u0637\u0629 \u0625\u0646\u0632\u064a\u0645\u0627\u062a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a\u060c \u0645\u0645\u0627 \u064a\u062c\u0639\u0644\u0647 \u0645\u062a\u0627\u062d\u064b\u0627 \u0628\u0634\u0643\u0644 \u0623\u0642\u0631\u0627\u0635 \u0641\u0645\u0648\u064a\u0629.<\/span><\/p>\n

\"\"
\u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0627\u0644\u0628\u0646\u0627\u0626\u064a \u0644\u0644\u0628\u0633\u064a\u0637 \u0644 (Orforglipron) \u0646\u0633\u0628\u064a\u0627\u064b \u0645\u0642\u0627\u0631\u0646\u0629 \u0628 (semaglutide) \u0645\u0645\u0627 \u064a\u0639\u0637\u064a \u0633\u0647\u0648\u0644\u0629 \u0641\u064a \u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0648\u0627\u0644\u0641\u0639\u0644 \u0627\u0644\u062d\u064a\u0648\u064a.<\/span><\/figcaption><\/figure>\n

\u0622\u0644\u064a\u0629 \u0627\u0644\u0639\u0645\u0644:<\/strong> \u0628\u0645\u062c\u0631\u062f \u062a\u0646\u0627\u0648\u0644\u0647 \u0648\u0627\u0645\u062a\u0635\u0627\u0635\u0647\u060c \u064a\u0642\u0648\u0645 \u0623\u0648\u0631\u0641\u0648\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0628\u0645\u0627 \u064a\u0644\u064a:<\/span>
\n1. \u062a\u062d\u0641\u064a\u0632 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0627\u0644\u0645\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0627\u0644\u062c\u0644\u0648\u0643\u0648\u0632: \u064a\u0634\u062c\u0639 \u062e\u0644\u0627\u064a\u0627 \u0628\u064a\u062a\u0627 \u0641\u064a \u0627\u0644\u0628\u0646\u0643\u0631\u064a\u0627\u0633 \u0639\u0644\u0649 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0623\u0646\u0633\u0648\u0644\u064a\u0646 \u0639\u0646\u062f\u0645\u0627 \u062a\u0631\u062a\u0641\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0633\u0643\u0631 \u0641\u064a \u0627\u0644\u062f\u0645\u060c \u0645\u0645\u0627 \u064a\u0633\u0627\u0639\u062f \u0639\u0644\u0649 \u062e\u0641\u0636\u0647\u0627 [<\/span>\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u062c\u0644\u0648\u0643\u0627\u062c\u0648\u0646 \u0627\u0644\u0630\u064a \u064a\u0631\u0641\u0639 \u0633\u0643\u0631 \u0627\u0644\u062f\u0645].<\/span>
\n2. \u0625\u0628\u0637\u0627\u0621 \u0625\u0641\u0631\u0627\u063a \u0627\u0644\u0645\u0639\u062f\u0629: \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0634\u0639\u0648\u0631 \u0623\u0633\u0631\u0639 \u0648\u0623\u0637\u0648\u0644 \u0628\u0627\u0644\u0627\u0645\u062a\u0644\u0627\u0621 \u0628\u0639\u062f \u0627\u0644\u0623\u0643\u0644.<\/span>
\n3. \u062a\u062b\u0628\u064a\u0637 \u0627\u0644\u0634\u0647\u064a\u0629 \u0641\u064a \u0627\u0644\u0645\u0631\u0627\u0643\u0632 \u0627\u0644\u062f\u0645\u0627\u063a\u064a\u0629: \u064a\u0624\u062b\u0631 \u0645\u0628\u0627\u0634\u0631\u0629 \u0639\u0644\u0649 \u0645\u0631\u0627\u0643\u0632 \u0627\u0644\u0634\u0628\u0639 \u0641\u064a \u0627\u0644\u062f\u0645\u0627\u063a\u060c \u0645\u0645\u0627 \u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u0634\u0639\u0648\u0631 \u0628\u0627\u0644\u062c\u0648\u0639 \u0648\u0643\u0645\u064a\u0629 \u0627\u0644\u0637\u0639\u0627\u0645 \u0627\u0644\u0645\u062a\u0646\u0627\u0648\u0644\u0629.<\/span><\/p>\n

\u0631\u062d\u0644\u0629 \u0627\u0644\u062a\u0637\u0648\u0631: \u0645\u0646 \u0627\u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0625\u0644\u0649 \u0627\u0644\u0627\u0628\u062a\u0643\u0627\u0631<\/strong><\/span>
\n\u0628\u062f\u0623\u062a \u0642\u0635\u0629 \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0641\u064a \u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0634\u0631\u0643\u0629 (Chugai Pharmaceutical)\u060c \u0627\u0644\u062a\u0627\u0628\u0639\u0629 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 (Roche Group)\u060c \u062d\u064a\u062b \u062a\u0645 \u0627\u0643\u062a\u0634\u0627\u0641\u0647 \u0643\u062c\u0632\u064a\u0621 \u0635\u063a\u064a\u0631 \u063a\u064a\u0631 \u0628\u0628\u062a\u064a\u062f\u064a \u064a\u062d\u0627\u0643\u064a \u062a\u0623\u062b\u064a\u0631 (GLP-1)\u060c \u0627\u0644\u0647\u0631\u0645\u0648\u0646 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0627\u0644\u0630\u064a \u064a\u0646\u0638\u0645 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0633\u0643\u0631 \u0641\u064a \u0627\u0644\u062f\u0645 \u0648\u064a\u0642\u0644\u0644 \u0627\u0644\u0634\u0647\u064a\u0629. \u0641\u064a \u0639\u0627\u0645 2018\u060c \u0631\u062e\u0635\u062a \u062a\u0634\u0648\u063a\u0627\u064a \u0627\u0644\u062f\u0648\u0627\u0621 \u0644\u0634\u0631\u0643\u0629 (Eli Lilly) \u0645\u0642\u0627\u0628\u0644 50 \u0645\u0644\u064a\u0648\u0646 \u062f\u0648\u0644\u0627\u0631 \u0623\u0648\u0644\u064a\u0629\u060c \u0645\u0639 \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u062d\u0635\u0648\u0644\u0647\u0627 \u0639\u0644\u0649 \u062a\u0639\u0648\u064a\u0636\u0627\u062a \u0625\u0636\u0627\u0641\u064a\u0629 \u062a\u0635\u0644 \u0625\u0644\u0649 1.2 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631 \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0627\u0644\u0645\u0639\u0627\u0644\u0645 \u0627\u0644\u062a\u0637\u0648\u064a\u0631\u064a\u0629. <\/span><\/p>\n

\u0643\u0627\u0646 \u0647\u0630\u0627 \u0627\u0644\u062a\u0631\u062e\u064a\u0635 \u062e\u0637\u0648\u0629 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0644\u0644\u064a\u0644\u064a\u060c \u0627\u0644\u062a\u064a \u0643\u0627\u0646\u062a \u062a\u0628\u062d\u062b \u0639\u0646 \u0628\u062f\u064a\u0644 \u0641\u0645\u0648\u064a \u0644\u0623\u062f\u0648\u064a\u062a\u0647\u0627 \u0627\u0644\u062d\u0642\u0646\u064a\u0629 \u0627\u0644\u0646\u0627\u062c\u062d\u0629\u060c \u062e\u0627\u0635\u0629 \u0645\u0639 \u062a\u0632\u0627\u064a\u062f \u0627\u0644\u0637\u0644\u0628 \u0639\u0644\u0649 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0645\u0646\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629. \u0634\u0631\u0643\u0629 (Eli Lilly) \u062a\u064f\u0639\u062f \u0623\u0643\u0628\u0631 \u0634\u0631\u0643\u0627\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0639\u0627\u0644\u0645\u064a\u064b\u0627\u060c \u0628\u0642\u064a\u0645\u0629 \u0633\u0648\u0642\u064a\u0629 \u062a\u062a\u062c\u0627\u0648\u0632 700 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631\u060c \u0645\u0627 \u064a\u062c\u0639\u0644\u0647\u0627 \u0623\u0643\u0628\u0631 \u0634\u0631\u0643\u0629 \u062f\u0648\u0627\u0626\u064a\u0629 \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645. \u062a\u0631\u0643\u0632 \u0639\u0644\u0649 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0627\u0644\u0633\u0645\u0646\u0629\u060c \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u060c \u0648\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0648\u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629\u060c \u0645\u0639 \u0627\u0633\u062a\u062b\u0645\u0627\u0631\u0627\u062a \u0636\u062e\u0645\u0629 \u0641\u064a \u0627\u0644\u0628\u062d\u062b \u0648\u0627\u0644\u062a\u0637\u0648\u064a\u0631.<\/span><\/p>\n

\"\"
\u0634\u0639\u0627\u0631 \u0634\u0631\u0643\u0629 \u0644\u064a\u0644\u064a<\/span><\/figcaption><\/figure>\n

\u0645\u0646\u0630 \u0630\u0644\u0643 \u0627\u0644\u062d\u064a\u0646\u060c \u062f\u062e\u0644 \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0645\u0631\u0627\u062d\u0644 \u0627\u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629. \u0641\u064a \u0639\u0627\u0645 2020\u060c \u0623\u0643\u0645\u0644\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0623\u0648\u0644\u064a\u0629 (Phase 1) \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0648\u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629\u060c \u0645\u0645\u0627 \u0623\u0638\u0647\u0631 \u0642\u062f\u0631\u062a\u0647 \u0639\u0644\u0649 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a (GLP-1) \u0628\u0646\u0641\u0633 \u0642\u0648\u0629 \u0627\u0644\u062d\u0642\u0646\u060c \u062f\u0648\u0646 \u0627\u0644\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u062d\u0642\u0646. \u0628<\/span><\/p>\n

\u062d\u0644\u0648\u0644 \u0639\u0627\u0645 2022\u060c \u0628\u062f\u0623\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 (Phase 2)\u060c \u0648\u0627\u0644\u062a\u064a \u0646\u0634\u0631\u062a \u0646\u062a\u0627\u0626\u062c\u0647\u0627 \u0641\u064a \u0645\u062c\u0644\u0629 (NEJM) \u0641\u064a \u064a\u0648\u0646\u064a\u0648 2023. \u0623\u0638\u0647\u0631\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0646 \u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0623\u062f\u062a \u0625\u0644\u0649 \u0641\u0642\u062f\u0627\u0646 \u0648\u0632\u0646 \u064a\u0635\u0644 \u0625\u0644\u0649 14.7% \u0645\u0646 \u0648\u0632\u0646 \u0627\u0644\u062c\u0633\u0645 \u0641\u064a 36 \u0623\u0633\u0628\u0648\u0639\u064b\u0627\u060c \u0645\u0639 \u0627\u0646\u062e\u0641\u0627\u0636 \u0645\u0633\u062a\u0648\u064a\u0627\u062a (HbA1c) (\u0645\u0624\u0634\u0631 \u0627\u0644\u0633\u0643\u0631 \u0641\u064a \u0627\u0644\u062f\u0645) \u0628\u0646\u0633\u0628\u0629 1.5-2%. \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0625\u064a\u062c\u0627\u0628\u064a\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0623\u0628\u0631\u0632\u062a \u062a\u062d\u062f\u064a\u0627\u062a \u0645\u062b\u0644 \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u0645\u0639\u062f\u064a\u0629 (\u063a\u062b\u064a\u0627\u0646\u060c \u0625\u0633\u0647\u0627\u0644) \u0627\u0644\u0645\u0634\u0627\u0628\u0647\u0629 \u0644\u0623\u062f\u0648\u064a\u0629 (GLP-1) \u0627\u0644\u0623\u062e\u0631\u0649.<\/span><\/p>\n

\u0645\u0639 \u0646\u0647\u0627\u064a\u0629 2023\u060c \u0627\u0646\u062a\u0642\u0644 \u0627\u0644\u062f\u0648\u0627\u0621 \u0625\u0644\u0649 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 (Phase 3)\u060c \u0636\u0645\u0646 \u0628\u0631\u0646\u0627\u0645\u062c\u064a\u0646 \u0631\u0626\u064a\u0633\u064a\u064a\u0646: (ATTAIN) \u0644\u0644\u0633\u0645\u0646\u0629\u060c \u0648(ACHIEVE) \u0644\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a. \u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0634\u0647\u062f\u062a \u062a\u0648\u0633\u0639\u064b\u0627 \u0641\u064a \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u062f\u0631\u0627\u0633\u0627\u062a \u0644\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0648\u0632\u0646\u060c \u0648\u062a\u0623\u062b\u064a\u0631\u0647 \u0639\u0644\u0649 \u0627\u0644\u062f\u0647\u0648\u0646 \u0627\u0644\u062c\u0633\u0645\u064a\u0629\u060c \u0648\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0627\u0644\u0645\u0628\u0627\u0634\u0631\u0629 \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u0645\u0646\u0627\u0641\u0633\u0629.<\/span><\/p>\n

\u0628\u062d\u0644\u0648\u0644 2024\u060c \u0623\u0643\u0645\u0644\u062a \u0644\u064a\u0644\u064a \u062b\u0644\u0627\u062b \u062f\u0631\u0627\u0633\u0627\u062a [Phase 1&2&3] \u0646\u0627\u062c\u062d\u0629\u060c \u0645\u0645\u0627 \u0645\u0647\u062f \u0627\u0644\u0637\u0631\u064a\u0642 \u0644\u0644\u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a. \u0647\u0630\u0647 \u0627\u0644\u0631\u062d\u0644\u0629 \u062a\u0639\u0643\u0633 \u062a\u0637\u0648\u0631\u064b\u0627 \u0633\u0631\u064a\u0639\u064b\u0627\u060c \u0645\u062f\u0641\u0648\u0639\u064b\u0627 \u0628\u0627\u0644\u062d\u0627\u062c\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0633\u0647\u0644\u0629 \u0627\u0644\u0648\u0635\u0648\u0644\u060c \u062d\u064a\u062b \u064a\u064f\u0642\u062f\u0631 \u0623\u0646 \u0627\u0644\u0633\u0645\u0646\u0629 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0623\u0643\u062b\u0631 \u0645\u0646 \u0645\u0644\u064a\u0627\u0631 \u0634\u062e\u0635 \u0639\u0627\u0644\u0645\u064a\u064b\u0627\u060c \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0639\u0644\u0649 500 \u0645\u0644\u064a\u0648\u0646.<\/span><\/p>\n

\"\"
\u0628\u0639\u0636 \u0623\u062f\u0648\u064a\u0629 \u062d\u0641\u0646 \u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u0633\u0643\u0631\u064a<\/span><\/figcaption><\/figure>\n

\u0623\u0647\u0645 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629: \u0623\u062f\u0644\u0629 \u0639\u0644\u0645\u064a\u0629 \u0642\u0648\u064a\u0629<\/strong><\/span>
\n\u062a\u0634\u0643\u0644 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u0645\u0627\u062f \u0646\u062c\u0627\u062d \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646. \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0641\u064a (Phase 2) \u060c \u0627\u0644\u062a\u064a \u0634\u0645\u0644\u062a 272 \u0645\u0634\u0627\u0631\u0643\u064b\u0627 \u0628\u0627\u0644\u063a\u064b\u0627 \u0645\u0635\u0627\u0628\u064b\u0627 \u0628\u0627\u0644\u0633\u0645\u0646\u0629\u060c \u0623\u0638\u0647\u0631\u062a \u0641\u0642\u062f\u0627\u0646 \u0648\u0632\u0646 \u0645\u062a\u0648\u0633\u0637 \u064a\u0635\u0644 \u0625\u0644\u0649 9.4 \u0643\u062c\u0645 (14.7% \u0645\u0646 \u0627\u0644\u0648\u0632\u0646 \u0627\u0644\u0623\u0648\u0644\u064a) \u0641\u064a \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 (45 \u0645\u062c\u0645 \u064a\u0648\u0645\u064a\u064b\u0627)\u060c \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u06402.3% \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0648\u0647\u0645\u064a. \u0643\u0645\u0627 \u0627\u0646\u062e\u0641\u0636 (HbA1c) \u0628\u0646\u0633\u0628\u0629 1.7%\u060c \u0645\u0639 \u062a\u062d\u0633\u0646 \u0641\u064a \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648\u0627\u0644\u0643\u0648\u0644\u064a\u0633\u062a\u0631\u0648\u0644. \u0646\u0634\u0631\u062a \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0641\u064a (NEJM)\u060c \u0645\u0624\u0643\u062f\u0629 \u0623\u0646 \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u064a\u062d\u0642\u0642 \u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0645\u0634\u0627\u0628\u0647\u0629 \u0644\u0644\u0633\u064a\u0645\u0627\u062c\u0644\u0648\u062a\u0627\u064a\u062f \u0627\u0644\u0641\u0645\u0648\u064a\u060c \u0644\u0643\u0646\u0647 \u0623\u0642\u0644 \u062a\u0643\u0644\u0641\u0629 \u0641\u064a \u0627\u0644\u0625\u0646\u062a\u0627\u062c \u0628\u0641\u0636\u0644 \u0643\u0648\u0646\u0647 \u062c\u0632\u064a\u0621 \u0635\u063a\u064a\u0631.<\/span><\/p>\n

\u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 (Phase 3)\u060c \u0628\u0631\u0632\u062a \u062f\u0631\u0627\u0633\u0629 (ATTAIN-1)\u060c \u0627\u0644\u062a\u064a \u0623\u0639\u0644\u0646\u062a \u0646\u062a\u0627\u0626\u062c\u0647\u0627 \u0641\u064a \u0623\u063a\u0633\u0637\u0633 2025. \u0634\u0645\u0644\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0643\u062b\u0631 \u0645\u0646 2000 \u0645\u0634\u0627\u0631\u0643 \u0645\u0635\u0627\u0628 \u0628\u0627\u0644\u0633\u0645\u0646\u0629 \u0623\u0648 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0648\u0632\u0646 \u0645\u0639 \u0623\u0645\u0631\u0627\u0636 \u0645\u0635\u0627\u062d\u0628\u0629\u060c \u0648\u0627\u0633\u062a\u0645\u0631\u062a 72 \u0623\u0633\u0628\u0648\u0639\u064b\u0627. \u0623\u062f\u0649 \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0625\u0644\u0649 \u0641\u0642\u062f\u0627\u0646 \u0648\u0632\u0646 \u0645\u062a\u0648\u0633\u0637 12.4 \u0643\u062c\u0645 (27.3 \u0631\u0637\u0644) \u0641\u064a \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629\u060c \u0623\u064a 12.4% \u0645\u0646 \u0627\u0644\u0648\u0632\u0646 \u0627\u0644\u0623\u0648\u0644\u064a\u060c \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u06402.2% \u0641\u064a \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0648\u0647\u0645\u064a. \u0643\u0645\u0627 \u062d\u0642\u0642 \u062a\u062d\u0633\u0646\u064b\u0627 \u0641\u064a \u0627\u0644\u0645\u0624\u0634\u0631\u0627\u062a \u0627\u0644\u0642\u0644\u0628\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629\u060c \u0645\u062b\u0644 \u062e\u0641\u0636 \u0627\u0644\u062f\u0647\u0648\u0646 \u0627\u0644\u062b\u0644\u0627\u062b\u064a\u0629 \u0628\u0646\u0633\u0628\u0629 20% \u0648\u062a\u062d\u0633\u064a\u0646 \u062d\u0633\u0627\u0633\u064a\u0629 \u0627\u0644\u0625\u0646\u0633\u0648\u0644\u064a\u0646.<\/span><\/p>\n

\u0623\u0645\u0627 \u062f\u0631\u0627\u0633\u0629 (ACHIEVE-1) \u060c \u0627\u0644\u0645\u062e\u0635\u0635\u0629 \u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0641\u0642\u062f \u0623\u0638\u0647\u0631\u062a \u0641\u064a \u0623\u0628\u0631\u064a\u0644 2025 \u0627\u0646\u062e\u0641\u0627\u0636 (HbA1c) \u0628\u0646\u0633\u0628\u0629 1.3-1.6% \u0639\u0628\u0631 \u0627\u0644\u062c\u0631\u0639\u0627\u062a\u060c \u0645\u0645\u0627 \u064a\u062c\u0639\u0644\u0647 \u0623\u0648\u0644 (GLP-1) \u0635\u063a\u064a\u0631 \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a \u064a\u0646\u062c\u062d \u0641\u064a (Phase 3).<\/span><\/p>\n

\u062f\u0631\u0627\u0633\u0629 \u0623\u062e\u0631\u0649 \u0647\u0627\u0645\u0629 \u0647\u064a (NCT06584916)\u060c \u0627\u0644\u062a\u064a \u062a\u0631\u0643\u0632 \u0639\u0644\u0649 \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0648\u0632\u0646 \u0628\u0639\u062f \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0627\u0644\u0647\u062f\u0641\u060c \u0648\u062f\u0631\u0627\u0633\u0629 (NCT0682405) \u0644\u0642\u064a\u0627\u0633 \u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u062f\u0648\u0627\u0621 \u0639\u0644\u0649 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u062c\u0633\u0645 (\u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u062f\u0647\u0648\u0646 \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u0639\u0636\u0644\u0627\u062a).<\/span><\/p>\n

\u0641\u064a \u0633\u0628\u062a\u0645\u0628\u0631 2025\u060c \u0646\u0634\u0631\u062a (NEJM) \u062f\u0631\u0627\u0633\u0629 (head-to-head) (\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0628\u0627\u0634\u0631\u0629) \u0645\u0639 \u0627\u0644\u0633\u064a\u0645\u0627\u062c\u0644\u0648\u062a\u0627\u064a\u062f \u0627\u0644\u0641\u0645\u0648\u064a\u060c \u062d\u064a\u062b \u0623\u0638\u0647\u0631 \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u062a\u0641\u0648\u0642\u064b\u0627 \u0641\u064a \u062e\u0641\u0636 (HbA1c) \u0628\u0646\u0633\u0628\u0629 2.2% \u0645\u0642\u0627\u0628\u0644 1.4%\u060c \u0648\u0641\u0642\u062f\u0627\u0646 \u0648\u0632\u0646 \u0623\u0639\u0644\u0649 \u0628\u0646\u0633\u0628\u0629 15%. \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a\u060c \u0627\u0644\u062a\u064a \u0634\u0645\u0644\u062a \u0622\u0644\u0627\u0641 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646\u060c \u0623\u0643\u062f\u062a \u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u062f\u0648\u0627\u0621\u060c \u0645\u0639 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u0628\u0646\u0633\u0628\u0629 40-50% \u0641\u064a \u0627\u0644\u0628\u062f\u0627\u064a\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u062a\u0642\u0644 \u062a\u062f\u0631\u064a\u062c\u064a\u064b\u0627. \u0643\u0645\u0627 \u0623\u0628\u0631\u0632\u062a \u0641\u0639\u0627\u0644\u064a\u062a\u0647 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0645\u062a\u0646\u0648\u0639\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0643\u0628\u0627\u0631 \u0627\u0644\u0633\u0646 \u0648\u0627\u0644\u0645\u0631\u0636\u0649 \u0630\u0648\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629.<\/span><\/p>\n

\"\"
\u062f\u0648\u0627\u0621 (semaglutide) \u0627\u0644\u0641\u0645\u0648\u064a<\/span><\/figcaption><\/figure>\n

\u0622\u062e\u0631 \u0627\u0644\u0623\u062e\u0628\u0627\u0631 \u0627\u0644\u0639\u0644\u0645\u064a\u0629: \u0625\u0646\u062c\u0627\u0632\u0627\u062a 2025<\/strong><\/span>
\n\u0623\u0641\u0627\u062f\u062a \u0631\u0648\u064a\u062a\u0631\u0632 \u0623\u0646 \u0644\u064a\u0644\u064a \u062a\u062e\u0637\u0637 \u0644\u0625\u0637\u0644\u0627\u0642 \u0627\u0644\u062f\u0648\u0627\u0621 \u0641\u064a \u0627\u0644\u0647\u0646\u062f \u0628\u0646\u0647\u0627\u064a\u0629 2025\u060c \u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0633\u0648\u0642\u064b\u0627 \u064a\u0639\u0627\u0646\u064a \u0645\u0646 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u0633\u0645\u0646\u0629. \u0643\u0630\u0644\u0643\u060c \u062a\u062a\u0648\u0642\u0639 \u0627\u0644\u0634\u0631\u0643\u0629 \u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0640 (FDA) \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0628\u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u0639\u0627\u0645\u060c \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0629. \u0647\u0630\u0647 \u0627\u0644\u0623\u062e\u0628\u0627\u0631 \u062a\u0639\u0632\u0632 \u0645\u0643\u0627\u0646\u0629 \u0627\u0644\u062f\u0648\u0627\u0621\u060c \u062e\u0627\u0635\u0629 \u0645\u0639 \u062a\u062d\u062f\u064a\u0627\u062a \u0627\u0644\u0625\u0646\u062a\u0627\u062c \u0641\u064a \u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062d\u0642\u0646.<\/span><\/p>\n

\u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0644\u0645\u062a\u0648\u0642\u0639: \u0622\u0641\u0627\u0642 \u0648\u062a\u062d\u062f\u064a\u0627\u062a<\/span><\/strong>
\n\u064a\u064f\u062a\u0648\u0642\u0639 \u0644\u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0645\u0633\u062a\u0642\u0628\u0644\u064b\u0627 \u0645\u0634\u0631\u0642\u064b\u0627\u060c \u0645\u0639 \u062a\u0642\u062f\u064a\u0645 \u0637\u0644\u0628 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0644\u0640 (FDA) \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0633\u0645\u0646\u0629 \u0641\u064a \u0627\u0644\u0631\u0628\u0639 \u0627\u0644\u0631\u0627\u0628\u0639 \u0645\u0646 2025\u060c \u0648\u0644\u0644\u0633\u0643\u0631\u064a \u0641\u064a \u0627\u0644\u0646\u0635\u0641 \u0627\u0644\u0623\u0648\u0644 \u0645\u0646 2026. \u064a\u064f\u0642\u062f\u0631 \u0645\u062d\u0644\u0644\u0648 \u0627\u0644\u0633\u0648\u0642 \u0623\u0646\u0647 \u0633\u064a\u062d\u0642\u0642 \u0645\u0628\u064a\u0639\u0627\u062a \u062a\u0635\u0644 \u0625\u0644\u0649 10 \u0645\u0644\u064a\u0627\u0631\u0627\u062a \u062f\u0648\u0644\u0627\u0631 \u0633\u0646\u0648\u064a\u064b\u0627 \u0628\u062d\u0644\u0648\u0644 2030\u060c \u0628\u0641\u0636\u0644 \u0633\u0647\u0648\u0644\u0629 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0648\u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0645\u0646\u062e\u0641\u0636\u0629 (\u062d\u0648\u0627\u0644\u064a 100-200 \u062f\u0648\u0644\u0627\u0631 \u0634\u0647\u0631\u064a\u064b\u0627\u060c \u0623\u0642\u0644 \u0645\u0646 \u0627\u0644\u062d\u0642\u0646). \u0643\u0645\u0627 \u064a\u064f\u062f\u0631\u0633 \u0641\u064a \u062f\u0631\u0627\u0633\u0627\u062a \u0625\u0636\u0627\u0641\u064a\u0629 \u0644\u0639\u0644\u0627\u062c \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645\u060c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0641\u0627\u0635\u0644\u060c \u0648\u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u062a\u0646\u0641\u0633 \u0623\u062b\u0646\u0627\u0621 \u0627\u0644\u0646\u0648\u0645\u060c \u0645\u0645\u0627 \u064a\u0648\u0633\u0639 \u0646\u0637\u0627\u0642\u0647.<\/span><\/p>\n

\"\"<\/p>\n

\u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u064a\u0648\u0627\u062c\u0647 “\u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646” \u062a\u062d\u062f\u064a\u0627\u062a \u0645\u062b\u0644 \u0627\u0644\u0645\u0646\u0627\u0641\u0633\u0629 \u0627\u0644\u0634\u062f\u064a\u062f\u0629 \u0645\u0646 \u0623\u062f\u0648\u064a\u0629 \u0646\u0648\u0641\u0648 \u0646\u0648\u0631\u062f\u064a\u0633\u0643 (\u0645\u062b\u0644 \u0623\u0645\u064a\u0643\u0631\u064a\u062a\u064a\u0646 \u0627\u0644\u0641\u0645\u0648\u064a\u060c \u0627\u0644\u0630\u064a \u064a\u062f\u062e\u0644 “Phase 3” \u0641\u064a 2026)\u060c \u0648\u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629 \u0646\u0633\u0628\u064a\u0627\u064b \u0627\u0644\u062a\u064a \u0642\u062f \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u0627\u0646\u0633\u062d\u0627\u0628 10-15% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649. \u0643\u0645\u0627 \u064a\u062d\u062a\u0627\u062c \u0625\u0644\u0649 \u062f\u0631\u0627\u0633\u0627\u062a \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f \u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u0642\u0644\u0628\u064a\u0629.<\/span><\/p>\n

\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0630\u0644\u0643\u060c \u064a\u064f\u0639\u062f \u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0645\u062b\u0627\u0644\u064b\u0627 \u0644\u0644\u0625\u0628\u062a\u0643\u0627\u0631\u060c \u062d\u064a\u062b \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0635\u0644 \u0625\u0644\u0649 \u0627\u0644\u0623\u0633\u0648\u0627\u0642 \u0627\u0644\u0646\u0627\u0634\u0626\u0629 \u0628\u0633\u0631\u0639\u0629\u060c \u0648\u064a\u0642\u0644\u0644 \u0627\u0644\u0639\u0628\u0621 \u0639\u0644\u0649 \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629. \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u060c \u0642\u062f \u064a\u064f\u062f\u0645\u062c \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u0623\u062e\u0631\u0649 \u0644\u062a\u0639\u0632\u064a\u0632 \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u062c\u0639\u0644\u0647 \u062c\u0632\u0621\u064b\u0627 \u0645\u0646 \u0639\u0644\u0627\u062c\u0627\u062a \u0645\u062e\u0635\u0635\u0629.<\/span><\/p><\/blockquote>\n

\u062e\u0627\u062a\u0645\u0629: \u062e\u0637\u0648\u0629 \u0646\u062d\u0648 \u0635\u062d\u0629 \u0623\u0641\u0636\u0644<\/span><\/strong><\/span>
\n\u0623\u0648\u0631\u0641\u0648\u0631\u062c\u0644\u064a\u0628\u0631\u0648\u0646 \u0631\u0645\u0632 \u0644\u0644\u062a\u0642\u062f\u0645 \u0627\u0644\u0637\u0628\u064a \u0627\u0644\u0630\u064a \u064a\u062c\u0639\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0645\u062a\u0627\u062d\u064b\u0627 \u0648\u0645\u0631\u064a\u062d\u064b\u0627. \u0645\u0646 \u0627\u0643\u062a\u0634\u0627\u0641\u0647 \u0641\u064a 2018 \u0625\u0644\u0649 \u0625\u0646\u062c\u0627\u0632\u0627\u062a 2025\u060c \u064a\u064f\u062b\u0628\u062a \u0623\u0646 \u0627\u0644\u0627\u0628\u062a\u0643\u0627\u0631 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0633\u0627\u0639\u062f \u0627\u0644\u0645\u0644\u0627\u064a\u064a\u0646. \u0645\u0639 \u0628\u064a\u0627\u0646\u0627\u062a\u0647 \u0627\u0644\u0642\u0648\u064a\u0629 \u0648\u0622\u0641\u0627\u0642\u0647 \u0627\u0644\u0648\u0627\u0639\u062f\u0629\u060c \u064a\u064f\u062a\u0648\u0642\u0639 \u0623\u0646 \u064a\u0644\u0639\u0628 \u062f\u0648\u0631\u064b\u0627 \u062d\u0627\u0633\u0645\u064b\u0627 \u0641\u064a \u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u0648\u0628\u0627\u0621 \u0627\u0644\u0635\u0627\u0645\u062a \u0644\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u0633\u0643\u0631\u064a.<\/span><\/p>\n

\u0638\u0647\u0648\u0631 \u0623\u062f\u0648\u064a\u0629 \u0645\u062b\u0644 (Orforglipron) \u064a\u0639\u0643\u0633 \u062a\u062d\u0648\u0644\u064b\u0627 \u0641\u064a \u0641\u0644\u0633\u0641\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0645\u0646 \u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f \u0639\u0644\u0649 \u0627\u0644\u062d\u0642\u0646 \u0627\u0644\u0628\u0627\u0647\u0638\u0629 \u0625\u0644\u0649 \u062d\u0644\u0648\u0644 \u0641\u0645\u0648\u064a\u0629 \u0645\u064a\u0633\u0648\u0631\u0629 \u0627\u0644\u062a\u0643\u0644\u0641\u0629.<\/span><\/p><\/blockquote>\n

\u0647\u0630\u0627 \u0627\u0644\u062a\u062d\u0648\u0644 \u0642\u062f \u064a\u064f\u0639\u064a\u062f \u062a\u0634\u0643\u064a\u0644 \u0627\u0644\u0639\u062f\u0627\u0644\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629\u060c \u0648\u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u0641\u062c\u0648\u0629 \u0628\u064a\u0646 \u0627\u0644\u062f\u0648\u0644 \u0627\u0644\u063a\u0646\u064a\u0629 \u0648\u0627\u0644\u0641\u0642\u064a\u0631\u0629 \u0641\u064a \u0627\u0644\u0648\u0635\u0648\u0644 \u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u0633\u0643\u0631\u064a.<\/span><\/p>\n

\u0643\u0645\u0627 \u064a\u0637\u0631\u062d \u0633\u0624\u0627\u0644\u064b\u0627 \u0623\u062e\u0644\u0627\u0642\u064a\u064b\u0627:<\/strong> \u0647\u0644 \u0633\u062a\u064f\u062a\u0627\u062d \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0641\u0639\u0644\u064b\u0627 \u0644\u0644\u062c\u0645\u064a\u0639\u061f \u0623\u0645 \u0633\u062a\u0638\u0644 \u0645\u062d\u0635\u0648\u0631\u0629 \u0641\u064a \u0627\u0644\u0623\u0633\u0648\u0627\u0642 \u0627\u0644\u0645\u0631\u0628\u062d\u0629\u061f<\/span><\/p>\n

\"\"
\u0627\u0644\u0635\u064a\u062f\u0644\u064a \u063a\u0633\u0627\u0646 \u0628\u0648 \u062e\u0645\u0633\u064a\u0646<\/span><\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

\u0627\u0644\u0633\u0645\u0646\u0629 \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a \u064a\u0634\u0643\u0644\u0627\u0646 \u0645\u0639\u064b\u0627 \u062b\u0646\u0627\u0626\u064a\u064b\u0627 \u0648\u0628\u0627\u0626\u064a\u064b\u0627 \u064a\u0647\u062f\u062f \u0627\u0644\u0635\u062d\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 \u0639\u0627\u0644\u0645\u064a\u064b\u0627… \u062e\u0644\u0642\u062a \u0647\u0630\u0647 \u0627\u0644\u0623\u0632\u0645\u0629 \u0633\u0648\u0642\u064b\u0627 \u0635\u062d\u064a\u0629 \u0636\u062e\u0645\u0629\u060c \u062a\u0634\u0645\u0644 \u0623\u062f\u0648\u064a\u0629 \u062e\u0641\u0636 \u0627\u0644\u0648\u0632\u0646\u060c \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u0630\u0627\u062a\u064a\u0629\u060c \u0648\u0627\u0644\u062c\u0631\u0627\u062d\u0627\u062a \u0627\u0644\u0623\u064a\u0636\u064a\u0629. \u062a\u064f\u0634\u0643\u0651\u0644 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0633\u0645\u0646\u0629 \u0639\u0628\u0626\u064b\u0627 \u0627\u0642\u062a\u0635\u0627\u062f\u064a\u064b\u0627 \u0645\u062a\u0632\u0627\u064a\u062f\u064b\u0627\u060c \u0625\u0630 \u062a\u062a\u0646\u0648\u0639 \u062a\u0643\u0627\u0644\u064a\u0641\u0647\u0627 \u0628\u064a\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062d\u062f\u064a\u062b\u0629 \u0645\u062b\u0644 \u0646\u0627\u0647\u0636\u0627\u062a (GLP-1)\u060c \u0648\u0627\u0644\u062c\u0631\u0627\u062d\u0627\u062a \u0645\u062b\u0644 \u062a\u0643\u0645\u064a\u0645 \u0627\u0644\u0645\u0639\u062f\u0629\u060c \u0648\u0627\u0644\u0628\u0631\u0627\u0645\u062c \u0627\u0644\u0633\u0644\u0648\u0643\u064a\u0629 \u0648\u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0631\u0642\u0645\u064a\u0629. \u062a\u062a\u0631\u0627\u0648\u062d \u062a\u0643\u0644\u0641\u0629 …<\/p>\n","protected":false},"author":4,"featured_media":31552,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[15,8],"tags":[],"class_list":["post-31541","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-15","category-8"],"_links":{"self":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/31541","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31541"}],"version-history":[{"count":3,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/31541\/revisions"}],"predecessor-version":[{"id":31553,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/31541\/revisions\/31553"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/media\/31552"}],"wp:attachment":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31541"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31541"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31541"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}