{"id":22638,"date":"2023-12-01T11:44:39","date_gmt":"2023-12-01T08:44:39","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=22638"},"modified":"2023-12-01T11:44:39","modified_gmt":"2023-12-01T08:44:39","slug":"%d8%af%d9%88%d9%86%d8%a7%d9%86%d9%8a%d9%85%d8%a7%d8%a8-%d8%a7%d9%84%d8%af%d9%88%d8%a7%d8%a1-%d8%a7%d9%84%d8%ab%d9%88%d8%b1%d9%8a-%d8%a7%d9%84%d8%b0%d9%8a-%d9%8a%d8%a8%d8%b4%d8%b1-%d8%a8%d8%b9","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=22638","title":{"rendered":"“\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”: \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u062b\u0648\u0631\u064a \u0627\u0644\u0630\u064a \u064a\u0628\u0634\u0631 \u0628\u0639\u0635\u0631 \u062c\u062f\u064a\u062f \u0641\u064a \u0639\u0644\u0627\u062c \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 – \u062a\u0631\u062c\u0645\u0629* \u0645\u062d\u0645\u062f \u062c\u0648\u0627\u062f \u0622\u0644 \u0627\u0644\u0633\u064a\u062f \u0646\u0627\u0635\u0631 \u0627\u0644\u062e\u0636\u0631\u0627\u0648\u064a"},"content":{"rendered":"

Donanemab: The Breakthrough Drug Ushering a New Era in Alzheimer\u2019s Treatment<\/strong>
\n (UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (UCSF) – \u0628\u0648\u0627\u0633\u0637\u0629: \u062c\u0627\u0645\u0639\u0629 \u0643\u0627\u0644\u064a\u0641\u0648\u0631\u0646\u064a\u0627 \u0641\u064a \u0633\u0627\u0646 \u0641\u0631\u0627\u0646\u0633\u064a\u0633\u0643\u0648)<\/span><\/h3>\n

\u0645\u0644\u062e\u0635 \u0627\u0644\u0645\u0642\u0627\u0644\u0629:<\/strong><\/span><\/p>\n

\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0648\u0627\u0641\u0642 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u062a\u062a\u0645 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u062f\u0648\u0627\u0621 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”\u060c \u0627\u0644\u0630\u064a \u064a\u0638\u0647\u0631 \u0646\u062a\u0627\u0626\u062c \u0648\u0627\u0639\u062f\u0629 \u0641\u064a \u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0627\u062f\u0631\u0627\u0643\u064a \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0627\u0644\u062e\u0641\u064a\u0641. \u0648\u0644\u0643\u0646 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0643\u0627\u0646\u062a \u0623\u0642\u0644 \u0648\u0636\u0648\u062d\u0627 \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629. \u0648\u064a\u0639\u062a\u0628\u0631 \u0647\u0630\u0627 \u0645\u062c\u0631\u062f \u0641\u0635\u0644 \u0627\u0641\u062a\u062a\u0627\u062d\u064a \u0641\u064a \u0639\u0635\u0631 \u062c\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0644\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0648\u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u062a\u0646\u0643\u0633\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0647.<\/span><\/p>\n

( \u0627\u0644\u0645\u0642\u0627\u0644\u0629 )<\/strong><\/span><\/p>\n

\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0648\u0627\u0641\u0642 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0639\u0644\u0649 \u0639\u0642\u0627\u0631 \u062b\u0627\u0644\u062b \u0644\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631\u060c \u0648\u0647\u0648 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0627\u0644\u062a\u0642\u062f\u0645 \u0641\u064a \u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u0645\u0631\u0636. \u0648\u0623\u0638\u0647\u0631 \u0627\u0644\u062f\u0648\u0627\u0621 \u062a\u0628\u0627\u0637\u0624 \u0627\u0644\u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0627\u062f\u0631\u0627\u0643\u064a \u0628\u0646\u0633\u0628\u0629 35% \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0631\u0636 [\u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631] \u062e\u0641\u064a\u0641\u060c \u0644\u0643\u0646 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0643\u0627\u0646\u062a \u0623\u0642\u0644 \u0648\u0636\u0648\u062d\u0627 \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a [\u0627\u0644\u0645\u0631\u0636\u064a\u0629] \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629.<\/span><\/strong><\/span><\/p>\n

\"\"
\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u062c\u062f\u064a\u062f \u0644\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” (Donanemab)\u060c \u0648\u0627\u0644\u0630\u064a \u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u062a\u0645 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u064a\u0647 \u0645\u0646 \u0642\u0628\u0644 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629\u060c \u064a\u0638\u0647\u0631 \u0646\u062a\u0627\u0626\u062c \u0648\u0627\u0639\u062f\u0629 \u0641\u064a \u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0627\u062f\u0631\u0627\u0643\u064a \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0631\u0636 [\u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631] \u062e\u0641\u064a\u0641. \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0630\u0644\u0643\u060c \u064a\u062c\u0628 \u062a\u0648\u062e\u064a \u0627\u0644\u062d\u0630\u0631 \u0628\u0633\u0628\u0628 \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u062e\u0637\u064a\u0631\u0629 \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629\u060c \u0648\u0642\u062f \u0623\u062b\u064a\u0631\u062a \u0645\u062e\u0627\u0648\u0641 \u0628\u0634\u0623\u0646 \u0639\u062f\u0645 \u0627\u0644\u062a\u0646\u0648\u0639 \u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0648\u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0645\u0631\u062a\u0641\u0639\u0629 \u0627\u0644\u0645\u062a\u0648\u0642\u0639\u0629 \u0644\u0644\u0639\u0644\u0627\u062c.<\/span><\/figcaption><\/figure>\u0627\u0644\u062a\u0642\u062f\u0645 \u0641\u064a \u0639\u0644\u0627\u062c \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631<\/strong><\/span><\/p>\n

\u0645\u0639 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0648\u0634\u064a\u0643\u0629 \u0639\u0644\u0649 \u062f\u0648\u0627\u0621 \u0622\u062e\u0631 \u0644\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0645\u0646 \u0642\u0628\u0644 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621\u060c \u064a\u0638\u0647\u0631 \u0627\u0644\u0645\u062c\u0627\u0644 \u0639\u0644\u0627\u0645\u0627\u062a \u0627\u0644\u062a\u0642\u062f\u0645 \u0641\u064a \u0627\u0644\u0645\u0639\u0631\u0643\u0629 \u0644\u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u0645\u0631\u0636.<\/span><\/p>\n

\u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u0641\u0625\u0646 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u062a\u0643\u0648\u0646 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u0646 \u0647\u0645 \u0641\u064a \u0627\u0644\u0645\u0631\u0627\u062d\u0644 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 \u0645\u0646 \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631. \u0648\u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u063a\u064a\u0644 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a (\u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u0641\u064a \u0627\u0644\u0637\u0628)\u060c \u0645\u062f\u064a\u0631 \u0645\u0631\u0643\u0632 \u0623\u0628\u062d\u0627\u062b \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0628\u062c\u0627\u0645\u0639\u0629 \u0643\u0627\u0644\u064a\u0641\u0648\u0631\u0646\u064a\u0627 – \u0633\u0627\u0646 \u0641\u0631\u0627\u0646\u0633\u064a\u0633\u0643\u0648 (UCSF)\u060c \u0633\u062a\u0643\u0648\u0646 \u0647\u0646\u0627\u0643 \u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u0639\u0644\u0627\u062c\u0627\u062a \u0625\u0636\u0627\u0641\u064a\u0629 \u0644\u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0631\u0636 [\u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631] \u0645\u062a\u0642\u062f\u0645.<\/span><\/p>\n

\u0648\u0642\u062f \u0627\u0642\u062a\u0631\u062d \u0623\u0646 \u0647\u0630\u0627 “\u0645\u062c\u0631\u062f \u0641\u0635\u0644 \u0627\u0641\u062a\u062a\u0627\u062d\u064a \u0641\u064a \u0639\u0635\u0631 \u062c\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0644\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0648\u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u062a\u0646\u0643\u0633\u064a\u0629 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0647”.<\/span><\/p>\n

“\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”: \u062f\u0648\u0627\u0621 \u062c\u062f\u064a\u062f \u0648\u0627\u0639\u062f \u0644\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631<\/strong><\/span><\/p>\n

\u0623\u062f\u0644\u0649 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u0628\u0647\u0630\u0647 \u0627\u0644\u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0641\u064a \u0645\u0642\u0627\u0644\u0629 \u0627\u0641\u062a\u062a\u0627\u062d\u064a\u0629 \u0645\u0635\u0627\u062d\u0628\u0629 \u0644\u0646\u062a\u0627\u0626\u062c \u0623\u062d\u062f\u062b \u062f\u0648\u0627\u0621\u060c “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”\u060c \u0627\u0644\u0645\u0646\u0634\u0648\u0631\u0629 \u0641\u064a 17 \u064a\u0648\u0644\u064a\u0648 2023\u060c \u0641\u064a \u0645\u062c\u0644\u0629 \u0627\u0644\u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u0637\u0628\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (JAMA). \u0648\u0645\u062b\u0644 \u0639\u0642\u0627\u0631\u064a \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0627\u0644\u0633\u0627\u0628\u0642\u064a\u0646\u060c “\u0623\u062f\u0648\u0643\u0627\u0646\u064a\u0648\u0645\u0627\u0628” (\u0623\u062f\u0648\u0647\u064a\u0644\u0645 Aduhelm) \u0648”\u0644\u064a\u0643\u0627\u0646\u064a\u0645\u0627\u0628” (\u0644\u064a\u0643\u064a\u0645\u0628\u064a Leqembi)\u060c \u0641\u0625\u0646 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u062c\u0633\u0645 \u0645\u0636\u0627\u062f \u0648\u062d\u064a\u062f \u0627\u0644\u0646\u0633\u064a\u0644\u0629. \u0648\u062a\u0647\u0627\u062c\u0645 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u062a\u0631\u0633\u0628\u0627\u062a \u0627\u0644\u062f\u0645\u0627\u063a \u0627\u0644\u0645\u0635\u0646\u0648\u0639\u0629 \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u064a\u0633\u0645\u0649 \u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f”\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u0639\u0637\u064a\u0644 \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u062e\u0644\u064a\u0629 \u0648\u062a\u0633\u0631\u064a\u0639 \u0627\u0646\u062a\u0634\u0627\u0631 \u0628\u0631\u0648\u062a\u064a\u0646 \u0622\u062e\u0631\u060c [\u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646] “\u062a\u0627\u0648”. \u0648\u064a\u0634\u0627\u0631\u0643 \u0643\u0644 \u0645\u0646 \u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f” \u0648\u0627\u0644\u0640”\u062a\u0627\u0648” \u0641\u064a \u062a\u0637\u0648\u0631 \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631.<\/span><\/p>\n

\u0648\u0623\u0634\u0627\u0631\u062a \u062a\u062c\u0631\u0628\u0629 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u0625\u0644\u0649 \u0623\u0646\u0647\u0627 \u0623\u0628\u0637\u0623\u062a \u0627\u0644\u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0627\u062f\u0631\u0627\u0643\u064a \u0628\u0646\u0633\u0628\u0629 35% \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0646\u062e\u0641\u0636\u0629 \u0625\u0644\u0649 \u0645\u062a\u0648\u0633\u0637\u0629 \u0645\u0646 [\u0628\u0631\u0648\u062a\u064a\u0646] “\u062a\u0627\u0648” \u0641\u064a \u0627\u0644\u062f\u0645\u0627\u063a. \u0648\u062a\u0645 \u0627\u0644\u0625\u0628\u0644\u0627\u063a \u0639\u0646 \u0646\u062a\u0627\u0626\u062c \u0645\u0645\u0627\u062b\u0644\u0629 \u0645\u0639 \u062f\u0648\u0627\u0621 “\u0644\u064a\u0643\u064a\u0645\u0628\u064a”\u060c \u0627\u0644\u0630\u064a \u062d\u0635\u0644 \u0639\u0644\u0649 \u0645\u0648\u0627\u0641\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u00a0\u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0641\u064a \u0648\u0642\u062a \u0633\u0627\u0628\u0642 \u0645\u0646 \u0627\u0644\u0634\u0647\u0631 (\u064a\u0648\u0644\u064a\u0648 2023). \u0648\u0639\u0644\u0627\u0648\u0629 \u0639\u0644\u0649 \u0630\u0644\u0643\u060c \u0643\u0627\u0646 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0641\u064a \u062a\u062c\u0631\u0628\u0629 \u062f\u0648\u0627\u0621 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u062e\u0637\u0631 \u0623\u0642\u0644 \u0628\u0646\u0633\u0628\u0629 40% \u0644\u0644\u062a\u0637\u0648\u0631 \u0645\u0646 \u0627\u0644\u0636\u0639\u0641 \u0627\u0644\u0625\u062f\u0631\u0627\u0643\u064a \u0627\u0644\u062e\u0641\u064a\u0641 \u0625\u0644\u0649 \u0627\u0644\u062e\u0631\u0641 \u0627\u0644\u062e\u0641\u064a\u0641\u060c \u0623\u0648 \u0645\u0646 \u0627\u0644\u062e\u0631\u0641 \u0627\u0644\u062e\u0641\u064a\u0641 \u0625\u0644\u0649 \u0627\u0644\u0645\u062a\u0648\u0633\u0637.<\/span><\/p>\n

\u0641\u0639\u0627\u0644\u064a\u0629 \u0648\u0645\u062e\u0627\u0637\u0631 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”<\/strong><\/span><\/p>\n

\u0648\u064f\u062c\u062f \u0623\u0646 \u0627\u0644\u0640”\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0641\u064a \u0625\u0632\u0627\u0644\u0629 \u062a\u0631\u0633\u0628\u0627\u062a \u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f” \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u062f\u0648\u0627\u0621 “\u0623\u062f\u0648\u0647\u064a\u0644\u0645” \u0648\u062f\u0648\u0627\u0621 “\u0644\u064a\u0643\u064a\u0645\u0628\u064a”. \u0643\u0645\u0627 \u0623\u0646\u0647 \u0623\u062f\u0649 \u0625\u0644\u0649 \u0627\u0646\u062e\u0641\u0627\u0636 \u062a\u0631\u0643\u064a\u0632\u0627\u062a \u0628\u0631\u0648\u062a\u064a\u0646 “\u062a\u0627\u0648” \u0641\u064a \u0627\u0644\u062f\u0645\u060c \u0648\u0644\u0643\u0646 \u0644\u064a\u0633 \u0641\u064a \u0645\u0646\u0637\u0642\u0629 \u0631\u0626\u064a\u0633\u064a\u0629 \u0645\u0646 \u0627\u0644\u062f\u0645\u0627\u063a.<\/span><\/p>\n

\u0648\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0648\u0627\u0639\u062f\u0629\u060c \u0634\u062f\u062f \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u0639\u0644\u0649 \u0627\u0644\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u062a\u062d\u0644\u064a\u0644 \u0634\u0627\u0645\u0644 \u0644\u0641\u0647\u0645 \u0643\u064a\u0641\u064a\u0629 \u062a\u0623\u062b\u064a\u0631 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0639\u0644\u0649 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0631\u0636\u0649.<\/span><\/p>\n

\u062d\u062f\u0648\u062f (\u0642\u064a\u0648\u062f) “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”<\/strong><\/span><\/p>\n

\u0623\u0638\u0647\u0631 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0631\u0636 [\u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631] \u0623\u0643\u062b\u0631 \u062a\u0642\u062f\u0645\u064b\u0627 \u0641\u0627\u0626\u062f\u0629 \u0642\u0644\u064a\u0644\u0629 \u0623\u0648 \u0645\u0639\u062f\u0648\u0645\u0629 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0630\u064a\u0646 \u062a\u0644\u0642\u0648\u0627 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a. \u0625\u0644\u0649 \u062c\u0627\u0646\u0628 \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u062e\u0637\u064a\u0631\u0629 \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629 \u0644\u0644\u062f\u0648\u0627\u0621\u060c \u0641\u0625\u0646 \u0647\u0630\u0627 \u0645\u0646 \u0634\u0623\u0646\u0647 \u0623\u0646 \u064a\u0634\u062c\u0639 \u0627\u0644\u062e\u0628\u0631\u0627\u0621 \u0639\u0644\u0649 “\u0627\u0633\u062a\u0647\u062f\u0627\u0641 \u062a\u0637\u0648\u064a\u0631 \u0639\u0644\u0627\u062c\u0627\u062a \u0623\u0643\u062b\u0631 \u062a\u0623\u062b\u064a\u0631\u064b\u0627 \u0648\u0623\u0643\u062b\u0631 \u0623\u0645\u0627\u0646\u064b\u0627”\u060c \u0643\u062a\u0628 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a\u060c \u0627\u0644\u0645\u0646\u062a\u0633\u0628 \u0625\u0644\u0649 \u0645\u0631\u0643\u0632 \u0627\u0644\u0630\u0627\u0643\u0631\u0629 \u0648\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u0643\u0627\u0644\u064a\u0641\u0648\u0631\u0646\u064a\u0627 \u0641\u064a \u0633\u0627\u0646 \u0641\u0631\u0627\u0646\u0633\u064a\u0633\u0643\u0648 \u0648\u0623\u0642\u0633\u0627\u0645 \u0637\u0628 \u0627\u0644\u0623\u0639\u0635\u0627\u0628 \u0648\u0627\u0644\u0623\u0634\u0639\u0629 \u0648\u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0627\u0644\u0637\u0628\u064a \u0627\u0644\u062d\u064a\u0648\u064a\u060c \u0648\u0643\u0630\u0644\u0643 \u0645\u0639\u0647\u062f \u0648\u064a\u0644 \u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0623\u0639\u0635\u0627\u0628.<\/span><\/p>\n

\u0648\u064a\u062c\u0628 \u0623\u0646 \u064a\u0642\u062a\u0635\u0631 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0646\u062e\u0641\u0636\u0629 \u0625\u0644\u0649 \u0645\u062a\u0648\u0633\u0637\u0629 \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 “\u062a\u0627\u0648”\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0645\u0631\u0636 [\u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631] \u062e\u0641\u064a\u0641. \u0648\u062a\u062c\u0631\u064a \u062a\u062c\u0627\u0631\u0628 \u0623\u062e\u0631\u0649 \u0644\u062a\u0642\u064a\u064a\u0645 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0648\u062d\u064a\u062f\u0629 \u0627\u0644\u0646\u0633\u064a\u0644\u0629 \u0641\u064a \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636 \u0642\u0628\u0644 \u0638\u0647\u0648\u0631 \u0627\u0644\u0623\u0639\u0631\u0627\u0636.<\/span><\/p>\n

\u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0648\u0627\u0644\u0627\u062d\u062a\u064a\u0627\u0637\u0627\u062a<\/strong><\/span><\/p>\n

\u0645\u062b\u0644 \u0639\u0642\u0627\u0631\u064a \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0627\u0644\u062c\u062f\u064a\u062f\u064a\u0646 \u0627\u0644\u0622\u062e\u0631\u064a\u0646\u060c \u0627\u0631\u062a\u0628\u0637 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u0628\u062a\u0634\u0648\u0647\u0627\u062a \u062a\u0635\u0648\u064a\u0631\u064a\u0629 \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f” (ARIA) \u0648\u0627\u0644\u062a\u064a \u0642\u062f \u062a\u0634\u0645\u0644 \u062a\u0648\u0631\u0645 \u0627\u0644\u062f\u0645\u0627\u063a \u0648\u0627\u0644\u0646\u0632\u064a\u0641 \u0627\u0644\u062f\u0642\u064a\u0642. \u062d\u062f\u062b\u062a \u062d\u0627\u0644\u0627\u062a \u062a\u0634\u0648\u0647\u0627\u062a \u062a\u0635\u0648\u064a\u0631\u064a\u0629 \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0640\u201d\u0623\u0645\u064a\u0644\u0648\u064a\u062f\u201d \u062e\u0637\u064a\u0631\u0629 \u0641\u064a 3.7% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u062b\u0644\u0627\u062b \u062d\u0627\u0644\u0627\u062a \u0648\u0641\u0627\u0629.<\/span><\/p>\n

\u0648\u0643\u0627\u0646\u062a \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0623\u0639\u0644\u0649 \u0628\u064a\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u0644\u062f\u064a\u0647\u0645 \u062c\u064a\u0646 “\u0627\u0628\u0648\u064a4” (APOE4) [\u064a\u0648\u0641\u0631 \u0647\u0630\u0627 \u0627\u0644\u062c\u064a\u0646 \u062a\u0639\u0644\u064a\u0645\u0627\u062a \u0644\u0635\u0646\u0639 \u0628\u0631\u0648\u062a\u064a\u0646 \u064a\u0633\u0645\u0649 \u0635\u0645\u064a\u0645 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0634\u062d\u0645\u064a \u0625\u064a[1]<\/sup><\/strong> (Apolipoprotein E)]\u060c \u0645\u0645\u0627 \u064a\u0632\u064a\u062f \u0645\u0646 \u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631. \u0648\u0644\u0647\u0630\u0627 \u0627\u0644\u0633\u0628\u0628\u060c \u064a\u0648\u0635\u064a \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u0628\u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0642\u0628\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0648\u062d\u064a\u062f\u0629 \u0627\u0644\u0646\u0633\u064a\u0644\u0629.<\/span><\/p>\n

\u0648\u0641\u064a \u062d\u064a\u0646 \u062a\u0645\u062a \u0625\u062f\u0627\u0631\u0629 \u062a\u0634\u0648\u0647\u0627\u062a \u062a\u0635\u0648\u064a\u0631\u064a\u0629 \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f” \u0628\u0634\u0643\u0644 \u0622\u0645\u0646 \u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0641\u0625\u0646 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u064a\u062d\u062b \u0639\u0644\u0649 \u062a\u0648\u062e\u064a \u0627\u0644\u062d\u0630\u0631 \u0645\u0639 \u062a\u062d\u0648\u0644 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0625\u0644\u0649 \u0645\u0645\u0627\u0631\u0633\u0629 \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645 \u0627\u0644\u062d\u0642\u064a\u0642\u064a. \u0648\u0647\u0648 \u064a\u062f\u0639\u0648 \u0625\u0644\u0649 \u0627\u0644\u062d\u062f \u0645\u0646 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0644\u0627\u062c\u0631\u0627\u0621 \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0628\u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a \u0627\u0644\u0639\u0627\u062f\u064a \u0642\u0628\u0644 \u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0648\u0625\u062c\u0631\u0627\u0621 \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0628\u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a \u0627\u0644\u0639\u0627\u062f\u064a\u060c \u0648\u0648\u0642\u0641 \u0627\u0644\u0639\u0644\u0627\u062c \u0623\u0648 \u062a\u0639\u0644\u064a\u0642\u0647 \u0641\u064a \u062d\u0627\u0644\u0629 \u062d\u062f\u0648\u062b \u062a\u0634\u0648\u0647\u0627\u062a \u062a\u0635\u0648\u064a\u0631\u064a\u0629 \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f”.<\/span><\/p>\n

\u0627\u0644\u0645\u062e\u0627\u0648\u0641 \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a\u0629 \u0648\u0627\u0644\u062c\u062f\u0648\u0649<\/strong><\/span><\/p>\n

\u0643\u0627\u0646 \u0623\u062d\u062f \u0627\u0644\u0642\u064a\u0648\u062f \u0627\u0644\u0645\u0647\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0647\u0648 \u0627\u0644\u0627\u0641\u062a\u0642\u0627\u0631 \u0625\u0644\u0649 \u0627\u0644\u062a\u0646\u0648\u0639 \u0627\u0644\u0639\u0631\u0642\u064a \u0648\u0627\u0644\u0627\u062b\u0646\u064a. \u0648\u0643\u0627\u0646 8.6% \u0641\u0642\u0637 \u0645\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u064a\u0646 \u0627\u0644\u0628\u0627\u0644\u063a \u0639\u062f\u062f\u0647\u0645 1251 \u0645\u0634\u0627\u0631\u0643\u064b\u0627 \u0645\u0646 \u063a\u064a\u0631 \u0627\u0644\u0628\u064a\u0636\u060c \u0645\u0645\u0627 \u0623\u062b\u0627\u0631 \u0645\u062e\u0627\u0648\u0641 \u0623\u062e\u0644\u0627\u0642\u064a\u0629 \u0628\u0634\u0623\u0646 “\u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u062a\u0639\u0645\u064a\u0645 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0639\u0644\u0649 \u0627\u0644\u0633\u0643\u0627\u0646 \u0627\u0644\u0623\u0643\u062b\u0631 \u0639\u0631\u0636\u0629 \u0644\u0644\u062e\u0637\u0631”. \u0648\u064a\u0634\u064a\u0631 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u0625\u0644\u0649 \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u062a\u064a \u0623\u0638\u0647\u0631\u062a \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u062e\u0631\u0641 \u0628\u064a\u0646 \u0627\u0644\u0633\u0643\u0627\u0646 \u0627\u0644\u0633\u0648\u062f \u0648\u0627\u0644\u0644\u0627\u062a\u064a\u0646\u064a\u064a\u0646.<\/span><\/p>\n

\u0648\u0628\u0627\u0644\u0646\u0638\u0631 \u0625\u0644\u0649 \u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0645\u0631\u062a\u0641\u0639\u0629 \u0627\u0644\u0645\u062a\u0648\u0642\u0639\u0629 \u0644\u0640 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628” \u0648\u0627\u0631\u062a\u0641\u0627\u0639 \u0627\u0644\u0637\u0644\u0628 \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u0645\u0631\u0636\u0649\u060c \u064a\u0642\u062a\u0631\u062d \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u062a\u062d\u062f\u064a\u062f \u0645\u062f\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u0648\u0642\u062a \u0627\u0644\u0644\u0627\u0632\u0645 \u0644\u0625\u0632\u0627\u0644\u0629 \u062a\u0631\u0633\u0628\u0627\u062a \u0627\u0644\u0640”\u0623\u0645\u064a\u0644\u0648\u064a\u062f” \u0645\u0646 \u0627\u0644\u062f\u0645\u0627\u063a. \u0648\u0630\u0643\u0631 \u0623\u0646 \u0647\u0630\u0627 \u0627\u0644\u0646\u0647\u062c “\u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0639\u0632\u0632 \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631 \u062c\u062f\u0648\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u0644\u0645\u0631\u0636\u0649 \u0648\u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0648\u0634\u0631\u0643\u0627\u062a \u0627\u0644\u062a\u0623\u0645\u064a\u0646 \u0648\u0627\u0644\u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0635\u062d\u064a\u0629”.<\/span><\/p>\n

*\u062a\u0645\u062a \u0627\u0644\u062a\u0631\u062c\u0645\u0629 \u0628\u062a\u0635\u0631\u0641<\/span><\/p>\n

\u0645\u0631\u0627\u062c\u0639:<\/strong><\/p>\n

    \n
  1. \u201cDonanemab in Early Symptomatic Alzheimer DiseaseThe TRAILBLAZER-ALZ 2 Randomized Clinical Trial\u201d by John R. Sims, MD; Jennifer A. Zimmer, MD; Cynthia D. Evans, PhD; Ming Lu, MD, MS, MPH; Paul Ardayfio, PhD; JonDavid Sparks, PhD; Alette M. Wessels, PhD; Sergey Shcherbinin, PhD; Hong Wang, PhD; Emel Serap Monkul Nery, MD; Emily C. Collins, PhD; Paul Solomon, PhD; Stephen Salloway, MD; Liana G. Apostolova, MD; Oskar Hansson, MD, PhD; Craig Ritchie, MD, PhD; Dawn A. Brooks, PhD; Mark Mintun, MD and Daniel M. Skovronsky, MD, PhD for the TRAILBLAZER-ALZ 2 Investigators, 17 July 2023,\u00a0JAMA<\/em>. DOI:\u00a010.1001\/jama.2023.13239<\/strong><\/a><\/span><\/li>\n
  2. \u201cAmyloid-Targeting Monoclonal Antibodies for Alzheimer Disease\u201d by Gil D. Rabinovici, MD and Renaud La Joie, PhD, 17 July 2023,\u00a0JAMA<\/em>. DOI:\u00a010.1001\/jama.2023.11703<\/strong><\/a><\/span><\/li>\n<\/ol>\n

    \u0627\u0644\u0645\u0624\u0644\u0641 \u0627\u0644\u0645\u0634\u0627\u0631\u0643 \u0644\u0644\u0648\u0631\u0642\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629: \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u064a\u0646\u0648 \u0644\u0627 \u062c\u0648\u064a \u0645\u0646 \u0645\u0631\u0643\u0632 \u0627\u0644\u0630\u0627\u0643\u0631\u0629 \u0648\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0628\u062c\u0627\u0645\u0639\u0629 \u0643\u0627\u0644\u064a\u0641\u0648\u0631\u0646\u064a\u0627 \u0641\u064a \u0633\u0627\u0646 \u0641\u0631\u0627\u0646\u0633\u064a\u0633\u0643\u0648 \u0648\u0642\u0633\u0645 \u0637\u0628 \u0627\u0644\u0623\u0639\u0635\u0627\u0628.<\/span><\/p>\n

    \u0627\u0644\u062a\u0645\u0648\u064a\u0644: \u064a\u062a\u0645 \u062f\u0639\u0645 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u0648\u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0644\u0627 \u062c\u0648\u064a \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u0645\u0639\u0627\u0647\u062f \u0627\u0644\u0648\u0637\u0646\u064a\u0629 \u0644\u0644\u0635\u062d\u0629 \u0648\u062c\u0645\u0639\u064a\u0629 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631.<\/span><\/p>\n

    \u0627\u0644\u0625\u0641\u0635\u0627\u062d\u0627\u062a: \u064a\u062a\u0644\u0642\u0649 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u0627\u0628\u064a\u0646\u0648\u0641\u064a\u062a\u0634\u064a \u062f\u0639\u0645\u064b\u0627 \u0628\u062d\u062b\u064a\u064b\u0627 \u0648\u064a\u0642\u062f\u0645 \u0627\u0633\u062a\u0634\u0627\u0631\u0627\u062a \u0645\u062f\u0641\u0648\u0639\u0629 \u0627\u0644\u0623\u062c\u0631 \u0644\u0634\u0631\u0643\u0629 \u0625\u0644\u064a \u0644\u064a\u0644\u064a (Eli Lilly)\u060c \u0627\u0644\u0634\u0631\u0643\u0629 \u0627\u0644\u0645\u0635\u0646\u0639\u0629 \u0644\u062f\u0648\u0627\u0621 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”. \u0644\u0644\u0625\u0641\u0635\u0627\u062d\u0627\u062a \u0627\u0644\u0623\u062e\u0631\u0649\u060c \u064a\u0631\u062c\u0649 \u0627\u0644\u0631\u062c\u0648\u0639 \u0625\u0644\u0649 \u0627\u0644\u0648\u0631\u0642\u0629 \u0627\u0644\u0639\u0644\u0645\u064a\u0629.<\/span><\/p>\n

    \u0627\u0644\u0645\u0635\u062f\u0631:<\/strong><\/p>\n

    https:\/\/scitechdaily.com\/donanemab-the-breakthrough-drug-ushering-a-new-era-in-alzheimers-treatment\/<\/a><\/p>\n

    \u0627\u0644\u0647\u0648\u0627\u0645\u0634:<\/p>\n[1] \u0635\u0645\u064a\u0645 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0634\u062d\u0645\u064a E (Apo-E) \u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646 \u064a\u0634\u0627\u0631\u0643 \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0644\u0644\u062f\u0647\u0648\u0646 \u0641\u064a \u062c\u0633\u0645 \u0627\u0644\u062b\u062f\u064a\u064a\u0627\u062a. \u0648\u0647\u0646\u0627\u0643 \u0646\u0648\u0639 \u0641\u0631\u0639\u064a \u0645\u062a\u0648\u0631\u0637 \u0641\u064a \u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629. \u0648\u064a\u062a\u0645 \u062a\u0631\u0645\u064a\u0632\u0647 \u0641\u064a \u0627\u0644\u0628\u0634\u0631 \u0628\u0648\u0627\u0633\u0637\u0629 \u0627\u0644\u062c\u064a\u0646 “\u0627\u0628\u0648\u064a” APOE.<\/p>\n

    \"\"
    \u0627\u0644\u0645\u0647\u0646\u062f\u0633 \u0645\u062d\u0645\u062f \u062c\u0648\u0627\u062f \u0622\u0644 \u0627\u0644\u0633\u064a\u062f \u0646\u0627\u0635\u0631 \u0627\u0644\u062e\u0636\u0631\u0627\u0648\u064a<\/span><\/figcaption><\/figure>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Donanemab: The Breakthrough Drug Ushering a New Era in Alzheimer\u2019s Treatment (UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (UCSF) – \u0628\u0648\u0627\u0633\u0637\u0629: \u062c\u0627\u0645\u0639\u0629 \u0643\u0627\u0644\u064a\u0641\u0648\u0631\u0646\u064a\u0627 \u0641\u064a \u0633\u0627\u0646 \u0641\u0631\u0627\u0646\u0633\u064a\u0633\u0643\u0648) \u0645\u0644\u062e\u0635 \u0627\u0644\u0645\u0642\u0627\u0644\u0629: \u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0648\u0627\u0641\u0642 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u062a\u062a\u0645 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u062f\u0648\u0627\u0621 “\u062f\u0648\u0646\u0627\u0646\u064a\u0645\u0627\u0628”\u060c \u0627\u0644\u0630\u064a \u064a\u0638\u0647\u0631 \u0646\u062a\u0627\u0626\u062c \u0648\u0627\u0639\u062f\u0629 \u0641\u064a \u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0627\u062f\u0631\u0627\u0643\u064a \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631 \u0627\u0644\u062e\u0641\u064a\u0641. \u0648\u0644\u0643\u0646 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0643\u0627\u0646\u062a \u0623\u0642\u0644 …<\/p>\n","protected":false},"author":4,"featured_media":22640,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[19],"tags":[],"class_list":["post-22638","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-19"],"_links":{"self":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/22638","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=22638"}],"version-history":[{"count":1,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/22638\/revisions"}],"predecessor-version":[{"id":22641,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/22638\/revisions\/22641"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/media\/22640"}],"wp:attachment":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=22638"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=22638"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=22638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}