{"id":17250,"date":"2022-08-23T10:02:16","date_gmt":"2022-08-23T07:02:16","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=17250"},"modified":"2022-08-23T10:02:16","modified_gmt":"2022-08-23T07:02:16","slug":"%d8%a8%d8%a7%d8%ad%d8%ab%d9%88%d9%86-%d9%8a%d9%83%d8%b4%d9%81%d9%88%d9%86-%d8%b9%d9%86-%d8%a2%d9%84%d9%8a%d8%a9-%d8%ac%d8%b2%d9%8a%d8%a6%d9%8a%d8%a9-%d8%ac%d8%af%d9%8a%d8%af%d8%a9-%d9%84%d8%ae%d8%b7","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=17250","title":{"rendered":"\u0628\u0627\u062d\u062b\u0648\u0646 \u064a\u0643\u0634\u0641\u0648\u0646 \u0639\u0646 \u0622\u0644\u064a\u0629 \u062c\u0632\u064a\u0626\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0644\u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646 – \u062a\u0631\u062c\u0645\u0629* \u0645\u062d\u0645\u062f \u062c\u0648\u0627\u062f \u0622\u0644 \u0627\u0644\u0633\u064a\u062f \u0646\u0627\u0635\u0631 \u0627\u0644\u062e\u0636\u0631\u0627\u0648\u064a"},"content":{"rendered":"

Researchers reveal new molecular mechanism for Parkinson’s disease risk<\/strong>
\n(University of Michigan – \u0628\u0648\u0627\u0633\u0637\u0629: \u062c\u0627\u0645\u0639\u0629 \u0645\u064a\u0634\u064a\u063a\u0627\u0646)\u00a0 <\/strong><\/span><\/h3>\n

\u0645\u0644\u062e\u0635 \u0627\u0644\u0645\u0642\u0627\u0644\u0629:<\/strong><\/span><\/p>\n

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( \u0627\u0644\u0645\u0642\u0627\u0644\u0629 )<\/strong><\/p>\n

\u0641\u064a \u062d\u0648\u0627\u0644\u064a \u062e\u064f\u0645\u0633 \u062d\u0627\u0644\u0627\u062a \u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646\u060c \u0627\u0646\u0638\u0631 \u0625\u0644\u0649 \u0628\u0631\u0648\u062a\u064a\u0646 \u0635\u063a\u064a\u0631 \u0645\u0639\u0637\u0644 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 (1)<\/sup> \u0643\u0639\u0627\u0645\u0644 \u062e\u0637\u0631\u060c \u0643\u0645\u0627 \u064a\u0642\u0648\u0644 \u0628\u0627\u062d\u062b\u0648\u0646 \u0645\u0646 \u062c\u0627\u0645\u0639\u0629 \u0645\u064a\u0634\u064a\u063a\u0627\u0646.<\/strong><\/span><\/p>\n

\"\"
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\u0648\u0627\u0644\u0622\u0646\u060c \u0627\u0643\u062a\u0634\u0641 \u0628\u0627\u062d\u062b\u0648 \u062c\u0627\u0645\u0639\u0629 \u0645\u064a\u0634\u064a\u063a\u0627\u0646 \u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u062a\u062d\u0648\u0631 \u064a\u0633\u0645\u0649 \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175 (TMEM175)(4)<\/sup> \u0643\u0639\u0627\u0645\u0644 \u062e\u0637\u0631 \u0641\u064a \u062d\u0648\u0627\u0644\u064a 20\u066a \u0645\u0646 \u062d\u0627\u0644\u0627\u062a \u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646\u060c \u0648\u0641\u064a\u0647 \u062a\u0628\u062f\u0623 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 \u0641\u064a \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u062f\u0645\u0627\u063a \u0627\u0644\u062a\u064a \u062a\u062a\u062d\u0643\u0645 \u0641\u064a \u0627\u0644\u062d\u0631\u0643\u0629 \u0628\u0627\u0644\u0641\u0634\u0644 \u0648\u0627\u0644\u0645\u0648\u062a. \u0648\u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u0645\u0639\u0647\u062f \u0627\u0644\u0648\u0637\u0646\u064a \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629\u060c \u064a\u0639\u062a\u0642\u062f \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0623\u0646 \u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646 \u0646\u0627\u062a\u062c \u0639\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 \u0648\u0627\u0644\u0628\u064a\u0626\u064a\u0629.<\/p>\n

\u0648\u0642\u062f \u0648\u062c\u062f \u0628\u0627\u062d\u062b\u0648 \u062c\u0627\u0645\u0639\u0629 \u0645\u064a\u0634\u064a\u063a\u0627\u0646 \u0623\u0646\u0647 \u0625\u0630\u0627 \u062a\u0645 \u0627\u0644\u062a\u062d\u0648\u0631\u060c \u0641\u0625\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175 \u0644\u0627 \u064a\u0646\u0638\u0645 \u0628\u0634\u0643\u0644 \u0635\u062d\u064a\u062d \u062d\u0645\u0648\u0636\u0629 \u0627\u0644\u0628\u064a\u0626\u0629 \u062f\u0627\u062e\u0644 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645. \u0648\u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0627\u0644\u062d\u0645\u0648\u0636\u0629 \u0641\u064a \u062a\u0644\u0643 \u0627\u0644\u0628\u064a\u0626\u0629 \u063a\u064a\u0631 \u0635\u062d\u064a\u062d\u0629\u060c \u0641\u0625\u0646 \u0627\u0644\u0625\u0646\u0632\u064a\u0645\u0627\u062a \u062f\u0627\u062e\u0644 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a \u062a\u062a\u0648\u0642\u0641 \u0639\u0646 \u0627\u0644\u0639\u0645\u0644 \u0628\u0634\u0643\u0644 \u0641\u0639\u0627\u0644\u060c \u0648\u0644\u0627 \u062a\u0633\u062a\u0637\u064a\u0639 \u0627\u0644\u0639\u0636\u064a\u0627\u062a \u0623\u062f\u0627\u0621 \u0623\u062f\u0648\u0627\u0631\u0647\u0627 \u0628\u0634\u0643\u0644 \u0635\u062d\u064a\u062d. \u0648\u0642\u062f \u062a\u0645 \u0646\u0634\u0631 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u062a\u0647\u0645 \u0641\u064a \u0645\u062c\u0644\u0629 “\u062e\u0644\u064a\u0629”.<\/p>\n

\u0648\u0642\u0627\u0644 \u0627\u0644\u0645\u0624\u0644\u0641 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0644\u0648\u0631\u0642\u0629 \u0627\u0644\u0628\u062d\u062b\u064a\u0629 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 “\u0647\u0627\u0648\u0643\u0633\u064a\u0646\u063a \u0627\u0643\u0633\u0648” (Haoxing Xu)\u060c \u0623\u0633\u062a\u0627\u0630 \u0639\u0644\u0645 \u0627\u0644\u0623\u062d\u064a\u0627\u0621 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u0648\u0627\u0644\u062e\u0644\u0648\u064a \u0648\u0627\u0644\u062a\u0637\u0648\u0631\u064a: “\u0641\u064a \u0627\u0644\u062d\u0642\u064a\u0642\u0629\u060c \u064a\u062d\u062a\u0627\u062c \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u062f\u0631\u062c\u0629 \u062d\u0645\u0648\u0636\u0629 \u0645\u062b\u0627\u0644\u064a\u0629. \u00a0\u062a\u0628\u0644\u063a 4.6 \u062a\u0642\u0631\u064a\u0628\u064b\u0627. \u0647\u0646\u0627 \u062a\u0634\u0628\u064a\u0647: \u062f\u0631\u062c\u0629 \u062d\u0631\u0627\u0631\u0629 \u0627\u0644\u062c\u0633\u0645 \u064a\u062c\u0628 \u0623\u0646 \u062a\u0643\u0648\u0646 37 \u062f\u0631\u062c\u0629 \u0645\u0626\u0648\u064a\u0629. \u062b\u0645\u0627\u0646\u064a\u0629 \u0648\u062b\u0644\u0627\u062b\u0648\u0646 \u0645\u0631\u062a\u0641\u0639 \u062c\u062f\u064b\u0627 \u0648 36 \u0645\u0646\u062e\u0641\u0636 \u062c\u062f\u064b\u0627”. \u0648\u062a\u0627\u0628\u0639: “\u062a\u062a\u0637\u0644\u0628 \u0627\u0644\u0625\u0646\u0632\u064a\u0645\u0627\u062a \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a \u062f\u0631\u062c\u0629 \u062d\u0645\u0648\u0636\u0629 \u062a\u0628\u0644\u063a 4.6 \u062a\u0642\u0631\u064a\u0628\u064b\u0627. \u0642\u062f \u064a\u062a\u0633\u0628\u0628 \u0623\u064a \u0634\u064a\u0621 \u062e\u0627\u0631\u062c \u062f\u0631\u062c\u0629 \u0627\u0644\u062d\u0645\u0648\u0636\u0629 4.6 \u0641\u064a \u062d\u062f\u0648\u062b \u062e\u0644\u0644 \u0641\u064a \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u062a\u0631\u0627\u0643\u0645 \u0627\u0644\u0642\u0645\u0627\u0645\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0641\u064a \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0625\u0644\u0649 \u062d\u062f\u0648\u062b \u062a\u0646\u0643\u0633 \u0639\u0635\u0628\u064a \u0648\u0623\u0645\u0631\u0627\u0636 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 (\u0623\u064a\u0636\u064a\u0629)”.<\/p>\n

\u0648\u0644\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u0641\u064a \u062d\u0627\u0644\u0629 \u062a\u0648\u0627\u0632\u0646 \u062d\u0645\u0636\u064a\u060c \u0639\u0631\u0641 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0627\u0643\u0633\u0648 \u0623\u0646\u0647 \u0644\u0627 \u0628\u062f \u0645\u0646 \u0648\u062c\u0648\u062f \u0642\u0646\u0627\u0629 \u0623\u064a\u0648\u0646\u064a\u0629 \u062a\u0646\u0638\u0645 \u062d\u0645\u0648\u0636\u0629 \u062a\u0644\u0643 \u0627\u0644\u0628\u064a\u0626\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0646\u0638\u064a\u0645 \u062a\u0631\u0643\u064a\u0632 \u0623\u064a\u0648\u0646\u0627\u062a \u0627\u0644\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646 (\u062a\u0633\u0645\u0649 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646\u0627\u062a \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0633\u064a\u0627\u0642 – \u0646\u0648\u0627\u0629 \u0630\u0631\u0629 \u0627\u0644\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646 \u0645\u0639 \u062a\u062c\u0631\u064a\u062f \u0627\u0644\u0630\u0631\u0629 \u0645\u0646 \u0625\u0644\u0643\u062a\u0631\u0648\u0646\u0647\u0627) \u062f\u0627\u062e\u0644 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645.<\/p>\n

\u0648\u0642\u0627\u0645 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0627\u0643\u0633\u0648\u060c \u0628\u0645\u0633\u0627\u0639\u062f\u0629 \u0627\u0644\u0645\u0624\u0644\u0641\u064a\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0648\u0645\u0646\u0647\u0645 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0631\u064a\u062a\u0634\u0627\u0631\u062f \u0647\u064a\u0648\u0645\u060c \u0623\u0633\u062a\u0627\u0630 \u0639\u0644\u0645 \u0627\u0644\u0623\u062d\u064a\u0627\u0621 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u0648\u0627\u0644\u062e\u0644\u0648\u064a \u0648\u0627\u0644\u0646\u0645\u0627\u0626\u064a \u0628\u062c\u0627\u0645\u0639\u0629 \u062c\u0627\u0645\u0639\u0629 \u0645\u064a\u0634\u064a\u063a\u0627\u0646\u060c \u0628\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u062d\u0645\u0648\u0636\u0629 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0644\u062a\u062c\u0648\u064a\u0641 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645. \u0648\u0628\u0639\u062f \u0630\u0644\u0643\u060c \u0642\u0627\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0628\u062a\u0645\u0634\u064a\u0637 \u0642\u0627\u0626\u0645\u0629 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u0648\u0644\u0643\u0646 \u0644\u0645 \u064a\u062a\u0645 \u0648\u0635\u0641\u0647\u0627 \u0628\u0634\u0643\u0644 \u062c\u064a\u062f \u0628\u0639\u062f.<\/p>\n

\u0648\u0645\u0627 \u062a\u0645 \u0641\u0647\u0645\u0647 \u062c\u064a\u062f\u064b\u0627 \u0647\u0648 \u0643\u064a\u0641\u064a\u0629 \u062f\u062e\u0648\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646\u0627\u062a \u0625\u0644\u0649 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a: \u0647\u0646\u0627\u0643 \u0646\u0627\u0642\u0644 \u063a\u0634\u0627\u0621 \u0645\u062d\u062f\u062f \u064a\u0633\u0645\u0649 \u0627\u0646\u0632\u064a\u0645 “\u0641\u064a-\u0627\u064a\u0647 \u062a\u064a \u0628\u064a\u0633” (V-ATPase) (5)<\/sup> \u064a\u0642\u0648\u0645 \u0628\u062a\u062d\u0645\u064a\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646\u0627\u062a\u060c \u0648\u0644\u0643\u0646 \u0645\u0627 \u0644\u0645 \u064a\u0643\u0646 \u0648\u0627\u0636\u062d\u064b\u0627 \u0647\u0648 \u0643\u064a\u0641\u064a\u0629 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0632\u0646\u060c \u0623\u0648 \u0643\u064a\u0641\u064a\u0629 \u0648\u0635\u0648\u0644 \u062f\u0631\u062c\u0629 \u0627\u0644\u062d\u0645\u0648\u0636\u0629 \u0625\u0644\u0649 4.6 \u0648\u0639\u062f\u0645 \u0627\u0644\u0633\u0645\u0627\u062d \u0644\u0647\u0627 \u0628\u0627\u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631. \u0648\u0623\u0643\u062b\u0631 \u062d\u0645\u0636\u064a\u0629\u060c \u062d\u0633\u0628 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0647\u064a\u0648\u0645. \u0648\u062a\u0634\u064a\u0631 \u0628\u0639\u0636 \u0627\u0644\u0623\u062f\u0644\u0629 \u063a\u064a\u0631 \u0627\u0644\u0645\u0628\u0627\u0634\u0631\u0629 \u0625\u0644\u0649 \u0648\u062c\u0648\u062f \u0642\u0646\u0627\u0629 \u0646\u0641\u0627\u0630\u0629 \u0644\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a \u0627\u0644\u062a\u064a \u0643\u0627\u0646 \u0623\u0633\u0627\u0633\u0647\u0627 \u0627\u0644\u062c\u0632\u064a\u0626\u064a \u063a\u064a\u0631 \u0645\u0639\u0631\u0648\u0641 \u0648\u0627\u0644\u062a\u064a \u0643\u0627\u0646\u062a \u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0637\u0631\u064a\u0642\u0629 \u0645\u0627 \u0628\u0627\u0633\u062a\u062a\u0628\u0627\u0628 \u062f\u0631\u062c\u0629 \u0627\u0644\u062d\u0645\u0648\u0636\u0629.<\/p>\n

\u0648\u0642\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0627\u0643\u0633\u0648: “\u0643\u0646\u0627 \u0645\u0647\u062a\u0645\u064a\u0646 \u0623\u0646\u0647 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0647\u0646\u0627\u0643 \u0627\u0646\u0632\u064a\u0645 “\u0641\u064a-\u0627\u064a\u0647 \u062a\u064a \u0628\u064a\u0633” \u0644\u0636\u062e \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0641\u064a\u0647\u060c \u0641\u064a\u062c\u0628 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a \u0628\u0631\u0648\u062a\u064a\u0646 \u0642\u0646\u0627\u0629 \u0623\u064a\u0648\u0646\u064a\u0629 \u0644\u0625\u0637\u0644\u0627\u0642 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u0648\u0646 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0645\u0631\u062a\u0641\u0639\u064b\u0627 \u062c\u062f\u064b\u0627 \u062f\u0627\u062e\u0644 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645”.<\/p>\n

\u0648\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0642\u0646\u0648\u0627\u062a \u0627\u0644\u0623\u064a\u0648\u0646\u064a\u0629 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u060c \u0637\u0648\u0631 \u0645\u062e\u062a\u0628\u0631 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0627\u0643\u0633\u0648 \u0633\u0627\u0628\u0642\u064b\u0627 \u062a\u0642\u0646\u064a\u0629 \u0645\u062a\u062e\u0635\u0635\u0629 \u062a\u0633\u0645\u0649 \u0645\u0634\u0628\u0643 \u062a\u0635\u062d\u064a\u062d \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645. \u0648\u064a\u0633\u0645\u062d \u0645\u0634\u0628\u0643 \u0627\u0644\u062a\u0635\u062d\u064a\u062d \u0644\u0644\u0628\u0627\u062d\u062b\u064a\u0646 “\u0628\u062a\u0634\u063a\u064a\u0644” \u0642\u0646\u0648\u0627\u062a \u0623\u064a\u0648\u0646\u064a\u0629 \u0645\u0639\u064a\u0646\u0629 \u0628\u0634\u0643\u0644 \u0627\u0646\u062a\u0642\u0627\u0626\u064a \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u0645\u0646 \u0623\u062c\u0644 \u0641\u0647\u0645 \u0648\u0638\u064a\u0641\u062a\u0647\u0627 \u0628\u0634\u0643\u0644 \u0623\u0641\u0636\u0644. \u0648\u0627\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0647\u0630\u0647 \u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0644\u0625\u064a\u062c\u0627\u062f \u0642\u0646\u0648\u0627\u062a \u0644\u0644\u0623\u064a\u0648\u0646\u0627\u062a \u0627\u0644\u0623\u062e\u0631\u0649: \u0627\u0644\u0643\u0627\u0644\u0633\u064a\u0648\u0645\u060c \u0648\u0627\u0644\u0635\u0648\u062f\u064a\u0648\u0645\u060c \u0648\u0627\u0644\u0628\u0648\u062a\u0627\u0633\u064a\u0648\u0645\u060c \u0648\u0627\u0644\u0643\u0644\u0648\u0631\u064a\u062f\u060c \u0648\u0627\u0644\u062d\u062f\u064a\u062f\u060c \u0648\u0627\u0644\u0622\u0646 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646\u0627\u062a.<\/p>\n

\u0648\u0642\u0627\u0645 \u0628\u0627\u062d\u062b\u0648 \u0645\u0627 \u0628\u0639\u062f \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u0648\u0627\u0644\u0645\u0624\u0644\u0641\u0648\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u0648\u0646 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u0645\u064a\u0634\u064a\u063a\u0627\u0646 \u0645\u064a\u0643\u064a\u0646 \u0647\u0648 \u0648\u0628\u0646\u063a \u0644\u064a \u0628\u0639\u0645\u0644 \u0642\u0627\u0626\u0645\u0629 \u0628\u062c\u0645\u064a\u0639 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0634\u0641\u0631 \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0623\u0646\u0647\u0627 \u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a\u060c \u062b\u0645 \u0642\u0627\u0645\u0648\u0627 \u0628\u0645\u0627 \u064a\u0633\u0645\u0649 \u0627\u062e\u062a\u0628\u0627\u0631 \u0641\u062d\u0635 \u0627\u0644\u0625\u0641\u0631\u0627\u0637 \u0641\u064a \u0627\u0644\u062a\u0639\u0628\u064a\u0631. \u0648\u0647\u0630\u0627 \u064a\u0639\u0646\u064a \u0623\u0646 \u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0627\u062e\u062a\u0628\u0631\u0648\u0627 \u0639\u0634\u0631\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u063a\u0634\u0627\u0626\u064a\u0629 \u0648\u0627\u062d\u062f\u064b\u0627 \u062a\u0644\u0648 \u0627\u0644\u0622\u062e\u0631 \u0644\u0645\u0639\u0631\u0641\u0629 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u063a\u0634\u0627\u0621 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u0623\u0635\u0628\u062d \u0623\u0643\u062b\u0631 \u0646\u0641\u0627\u0630\u064a\u0629 \u0644\u0644\u0628\u0631\u0648\u062a\u0648\u0646\u0627\u062a. \u0648\u0642\u062f \u064a\u0634\u064a\u0631 \u0647\u0630\u0627 \u0625\u0644\u0649 \u0623\u0646 \u0623\u062d\u062f \u0627\u0644\u0645\u0631\u0634\u062d\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u0642\u0627\u0645\u0648\u0627 \u0628\u0641\u062d\u0635\u0647\u0645 \u0643\u0627\u0646 \u0645\u0633\u0624\u0648\u0644\u0627\u064b \u0639\u0646 \u062a\u062f\u0641\u0642 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645.<\/p>\n

\u0631\u0643\u0632 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0639\u0644\u0649 \u0627\u0644\u063a\u0634\u0627\u0621 “\u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175” \u060c \u0648\u0627\u0644\u0630\u064a \u0623\u0639\u0637\u0649 \u0646\u0641\u0627\u0630\u064a\u0629 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0627\u0644\u0645\u062d\u0633\u0646\u0629 \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631 \u0641\u064a \u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u0641\u062d\u0635\u060c \u0643\u0645\u0627 \u0630\u0643\u0631 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0647\u064a\u0648\u0645.<\/p>\n

\u0648\u0642\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0647\u064a\u0648\u0645: “\u0644\u0642\u062f \u062c\u0639\u0644 \u0647\u0630\u0627 \u0645\u064a\u0643\u064a\u0646 \u0648\u0647\u0627\u0643\u0633\u064a\u0646\u063a \u0648\u0628\u0642\u064a\u0629 \u0627\u0644\u0639\u0627\u0645\u0644\u064a\u0646 \u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u0645\u062a\u062d\u0645\u0633\u064a\u0646 \u062d\u0642\u064b\u0627\u060c \u0644\u0623\u0646 \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0644\u0645 \u064a\u0643\u0646 \u0645\u0639\u0631\u0648\u0641\u064b\u0627 \u062a\u0645\u0627\u0645\u064b\u0627”. \u0648\u062a\u0627\u0628\u0639: “\u0627\u0644\u0623\u0647\u0645 \u0645\u0646 \u0630\u0644\u0643\u060c \u0623\u0646\u0647 \u0623\u062d\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0623\u0643\u062b\u0631 \u0639\u0631\u0636\u0629 \u0644\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0633\u0628\u0628 \u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646”.<\/p>\n

\u0648\u062a\u0631\u0643\u0632\u062a \u0627\u0644\u062a\u062e\u0645\u064a\u0646\u0627\u062a \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u062d\u0648\u0644 \u0643\u064a\u0641 \u0643\u0627\u0646 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0627\u0645\u0644 \u062e\u0637\u0631 \u0644\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646 \u062d\u0648\u0644 \u0641\u062d\u0635 \u0648\u0638\u064a\u0641\u062a\u0647 \u0643\u0642\u0646\u0627\u0629 \u0644\u0644\u0628\u0648\u062a\u0627\u0633\u064a\u0648\u0645.<\/p>\n

\u0648\u0642\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0647\u064a\u0648\u0645: “\u0628\u0635\u0631\u0627\u062d\u0629 \u062a\u0627\u0645\u0629\u060c \u0644\u0645 \u062a\u0643\u0646 \u0647\u0630\u0647 \u0627\u0644\u062a\u0641\u0633\u064a\u0631\u0627\u062a \u0645\u0646\u0637\u0642\u064a\u0629 \u0644\u0623\u0646\u0647 \u0645\u0646 \u0627\u0644\u0635\u0639\u0628 \u062a\u0628\u0631\u064a\u0631 \u0622\u0644\u064a\u0629 \u0645\u062b\u0644 \u062a\u063a\u064a\u064a\u0631 \u062a\u062f\u0641\u0642 \u0627\u0644\u0628\u0648\u062a\u0627\u0633\u064a\u0648\u0645 \u0639\u0628\u0631 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645 \u0643\u0627\u0646 \u064a\u062c\u0628 \u0623\u0646 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0639\u062c\u0632 \u0634\u0628\u064a\u0647 \u0628\u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646”. \u0648\u0623\u0636\u0627\u0641: “\u0648\u0644\u0643\u0646 \u0628\u0645\u062c\u0631\u062f \u0623\u0646 \u0623\u062f\u0631\u0643 \u0627\u0644\u0645\u0631\u0621 \u0623\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175 \u0631\u0628\u0645\u0627 \u0643\u0627\u0646 \u0642\u0646\u0627\u0629 \u0628\u0631\u0648\u062a\u0648\u0646\u064a\u0629\u060c \u0641\u0625\u0646 \u0627\u0644\u0623\u0633\u0627\u0633 \u0627\u0644\u0645\u0646\u0637\u0642\u064a \u0644\u0643\u064a\u0641\u064a\u0629 \u062d\u062f\u0648\u062b \u0637\u0641\u0631\u0629 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0641\u064a \u0627\u0644\u062a\u0633\u0628\u0628 \u0641\u064a \u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646 \u0628\u062f\u0627 \u0648\u0627\u0636\u062d\u064b\u0627 \u0644\u0644\u063a\u0627\u064a\u0629”.<\/p>\n

\u0648\u0642\u0627\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0628\u0645\u0631\u0627\u062c\u0639\u0629 \u0639\u0645\u0644\u0647\u0645 \u0628\u0637\u0631\u064a\u0642\u062a\u064a\u0646. \u0641\u0623\u0648\u0644\u0627\u060c \u0627\u0633\u062a\u062e\u062f\u0645 \u0637\u0627\u0644\u0628\u0627 \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0647 “\u0647\u0648” \u0648 “\u0633\u064a \u0648\u0627\u0646\u063a” \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0628\u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646\u060c \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0624\u0634\u0631\u0627\u062a \u0627\u0644\u0641\u0644\u0648\u0631\u0633\u0646\u062a \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a\u0629\u060c \u0644\u0642\u064a\u0627\u0633 \u062d\u0645\u0648\u0636\u0629 \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a \u0639\u0646\u062f\u0645\u0627 \u062a\u062e\u0644\u0635\u0648\u0627 \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175. \u0648\u062b\u0627\u0646\u064a\u064b\u0627\u060c \u0627\u0633\u062a\u062e\u062f\u0645\u0648\u0627 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u062a\u064a \u062a\u0631\u0627\u062c\u0639\u062a \u0642\u062f\u0631\u062a\u0647\u0627 \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175. \u0648\u0647\u0630\u0627 \u064a\u0639\u0646\u064a \u0623\u0646\u0647\u0645 \u0644\u0645 \u064a\u0635\u0646\u0639\u0648\u0627 \u0642\u0646\u0627\u0629 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0646\u0627\u0642\u0644\u0629 \u0647\u0630\u0647 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645\u0627\u062a \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0647\u0645. \u0648\u0623\u0638\u0647\u0631 \u0627\u0644\u0641\u0631\u064a\u0642 \u062a\u0631\u0627\u0643\u0645 “\u0623\u0644\u0641\u0627 \u0633\u064a\u0646\u0648\u0643\u0644\u064a\u0646” (alpha-synuclein) \u0641\u064a \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0646\u0643\u0648\u0628\u0629. \u0648\u0645\u0646 \u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0623\u0646 \u062a\u0631\u0627\u0643\u0645 \u0623\u0644\u0641\u0627 \u0633\u064a\u0646\u0648\u0643\u0644\u064a\u0646 \u0633\u0627\u0645 \u0641\u064a \u0645\u0631\u0636\u0649 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646.<\/p>\n

\u0648\u0641\u064a \u0643\u0644\u062a\u0627 \u0627\u0644\u062d\u0627\u0644\u062a\u064a\u0646\u060c \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0646\u062e\u0641\u0627\u0636\u064b\u0627 \u0641\u064a \u0627\u0644\u0646\u0634\u0627\u0637 \u0627\u0644\u0625\u0646\u0632\u064a\u0645\u064a \u0627\u0644\u0630\u064a \u064a\u0643\u0633\u0631 \u0627\u0644\u0646\u0641\u0627\u064a\u0627\u062a \u0627\u0644\u062e\u0644\u0648\u064a\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u062a\u0643\u062a\u0644\u0627\u062a \u0623\u0644\u0641\u0627 \u0633\u064a\u0646\u0648\u0643\u0644\u064a\u0646\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0623\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0639\u0628\u0631 \u0627\u0644\u063a\u0634\u0627\u0621 175 \u0643\u0627\u0646 \u0645\u0633\u0624\u0648\u0644\u0627\u064b \u0639\u0646 \u062a\u0646\u0638\u064a\u0645 \u0627\u0644\u062d\u0645\u0648\u0636\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0648\u062a\u062f\u0647\u0648\u0631\u0647\u0627.<\/p>\n

\u0648\u0642\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0627\u0643\u0633\u0648: “\u0641\u064a \u0627\u0644\u0646\u0647\u0627\u064a\u0629\u060c \u0646\u062d\u0646 \u0648\u0627\u062b\u0642\u0648\u0646 \u062c\u062f\u064b\u0627 \u0645\u0646 \u0623\u0646 \u0647\u0630\u0627 \u0647\u0648 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0630\u064a \u064a\u062a\u062d\u0643\u0645 \u0641\u064a \u062a\u0633\u0631\u0628 \u0627\u0644\u0628\u0631\u0648\u062a\u0648\u0646 \u0641\u064a \u0627\u0644\u0644\u064a\u0633\u0648\u0633\u0648\u0645”. \u0648\u0623\u0636\u0627\u0641: “\u0647\u0630\u0647 \u0627\u0644\u0648\u0631\u0642\u0629 \u0627\u0644\u0628\u062d\u062b\u064a\u0629 \u0645\u062b\u064a\u0631\u0629 \u0644\u0623\u0646 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u062a\u0635\u0627\u062f\u0641 \u0623\u0646\u0647\u0627 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062e\u0637\u0648\u0631\u0629 \u0644\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0645\u0631\u0636 \u0628\u0627\u0631\u0643\u0646\u0633\u0648\u0646”.<\/p>\n

*\u062a\u0645\u062a \u0627\u0644\u062a\u0631\u062c\u0645\u0629 \u0628\u062a\u0635\u0631\u0641<\/span><\/p>\n

\u0627\u0644\u0645\u0635\u062f\u0631:<\/p>\n

https:\/\/phys.org\/news\/2022-06-reveal-molecular-mechanism-parkinson-disease.html<\/a><\/p>\n

\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a: \u0645\u064a\u0643\u064a\u0646 \u0647\u0648 \u0648\u0622\u062e\u0631\u0648\u0646\u060c Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes,\u00a0Cell<\/em>\u00a0(2022).\u00a0DOI: 10.1016\/j.cell.2022.05.021<\/a><\/span><\/p>\n

\u0627\u0644\u0647\u0648\u0627\u0645\u0634:<\/strong><\/p>\n