{"id":16428,"date":"2022-06-04T10:59:47","date_gmt":"2022-06-04T07:59:47","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=16428"},"modified":"2022-06-04T10:59:47","modified_gmt":"2022-06-04T07:59:47","slug":"%d9%87%d9%84-%d8%aa%d8%b3%d8%aa%d8%b7%d9%8a%d8%b9-%d8%aa%d9%82%d9%86%d9%8a%d8%a9-%d8%a7%d9%84%d9%83%d8%b1%d8%b3%d8%a8%d8%b1-%d8%b9%d9%83%d8%b3-%d8%a3%d9%88-%d8%a5%d8%a8%d8%b7%d8%a7%d8%a1-%d8%a7","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=16428","title":{"rendered":"\u0647\u0644 \u062a\u0633\u062a\u0637\u064a\u0639 \u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u0643\u0631\u0633\u0628\u0631 \u0639\u0643\u0633 (\u0623\u0648 \u0625\u0628\u0637\u0627\u0621) \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 – \u0628\u0642\u0644\u0645 \u0627\u0644\u0645\u0647\u0646\u062f\u0633 \u0635\u0627\u062f\u0642 \u0639\u0644\u064a \u0627\u0644\u0642\u0637\u0631\u064a"},"content":{"rendered":"

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\u0642\u0627\u0644 \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0628\u064a\u062a\u0631 \u0643\u0627\u0645\u0628\u0644\u060c \u0643\u0628\u064a\u0631 \u0645\u0624\u0644\u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0648\u0631\u0626\u064a\u0633 \u0628\u0631\u0646\u0627\u0645\u062c \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0648\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u062c\u0633\u062f\u064a\u0629 \u0641\u064a \u0645\u0639\u0647\u062f \u0633\u0627\u0646\u062c\u0631 \u0641\u064a \u0643\u0627\u0645\u0628\u0631\u064a\u062f\u062c: “\u0627\u0644\u0645\u062b\u064a\u0631 \u0641\u064a \u0647\u0630\u0627 \u0627\u0644\u0639\u0645\u0644 \u0647\u0648 \u0623\u0646\u0647 \u0642\u062f \u062a\u0643\u0648\u0646 \u0647\u0646\u0627\u0643 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0634\u062a\u0631\u0643\u0629 \u0645\u0646 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0641\u064a \u0627\u0644\u0639\u0645\u0644”. “\u0641\u064a \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0633\u064a\u0643\u0648\u0646 \u0627\u0644\u0647\u062f\u0641 \u0647\u0648 \u0625\u0628\u0637\u0627\u0621 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0623\u0648 \u0627\u0644\u062a\u062f\u062e\u0644 \u0641\u064a\u0647\u0627\u060c \u0648\u0644\u0643\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0642\u0644 \u0646\u0631\u0649 \u062e\u064a\u0627\u0631\u064b\u0627 \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0647\u0630\u0627 \u0644\u0642\u064a\u0627\u0633 \u0627\u0644\u0639\u0645\u0631 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a”.<\/p>\n

\u061b\u061b\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0639\u0645\u0644\u064a\u0629 \u0645\u0639\u0642\u062f\u0629\u060c \u0644\u0643\u0646 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0639\u0644\u0645\u0627\u0621 \u064a\u0634\u062a\u0628\u0647\u0648\u0646 \u0641\u064a \u0623\u0646 \u0627\u0644\u062a\u0631\u0627\u0643\u0645 \u0627\u0644\u062a\u062f\u0631\u064a\u062c\u064a \u0644\u0644\u0637\u0641\u0631\u0627\u062a \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u064a\u0624\u062f\u064a \u062a\u062f\u0631\u064a\u062c\u064a\u064b\u0627 \u0625\u0644\u0649 \u062a\u062f\u0647\u0648\u0631 \u0642\u062f\u0631\u0629 \u0627\u0644\u062c\u0633\u0645 \u0639\u0644\u0649 \u0627\u0644\u0639\u0645\u0644 \u0628\u0634\u0643\u0644 \u0635\u062d\u064a\u062d\u061b\u061b<\/strong><\/span><\/p>\n

\u062a\u0634\u064a\u0631 \u0623\u062d\u062f\u062b \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u062a\u0641\u0643\u064a\u0631 \u062e\u0627\u0637\u0626\u060c \u0623\u0648 \u0641\u064a \u0623\u0641\u0636\u0644 \u0627\u0644\u0623\u062d\u0648\u0627\u0644 \u063a\u064a\u0631 \u0645\u0643\u062a\u0645\u0644\u060c \u0648\u062a\u0644\u0642\u064a \u0627\u0644\u0644\u0648\u0645 \u0628\u062f\u0644\u0627\u064b \u0645\u0646 \u0630\u0644\u0643 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 “\u0627\u0644\u0623\u0646\u0627\u0646\u064a\u0629” \u0627\u0644\u062a\u064a \u062a\u0631\u062a\u0641\u0639 \u0625\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0647\u064a\u0645\u0646\u0629 \u0641\u064a \u0633\u0646 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629.<\/p>\n

\u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u0639\u0645\u0644 \u0645\u0639 \u0627\u0644\u0639\u0644\u0645\u0627\u0621 \u0641\u064a \u0645\u0639\u0647\u062f \u0648\u064a\u0644\u0643\u0648\u0645-\u0625\u0645 \u0622\u0631 \u0633\u064a \u0643\u0627\u0645\u0628\u0631\u064a\u062f\u062c \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629\u060c \u062f\u0631\u0633 \u0643\u0627\u0645\u0628\u0644 \u0648\u0632\u0645\u0644\u0627\u0624\u0647 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0639\u0628\u0631 \u0627\u0644\u0641\u0626\u0629 \u0627\u0644\u0639\u0645\u0631\u064a\u0629 \u0645\u0646 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u062d\u062f\u064a\u062b\u064a \u0627\u0644\u0648\u0644\u0627\u062f\u0629 \u0625\u0644\u0649 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0641\u064a \u0627\u0644\u0633\u0628\u0639\u064a\u0646\u064a\u0627\u062a \u0648\u0627\u0644\u062b\u0645\u0627\u0646\u064a\u0646\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0639\u0645\u0631 \u0641\u0648\u062c\u062f\u0648\u0627 \u0623\u0646 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u062a\u0642\u0644 \u0623\u0639\u0645\u0627\u0631\u0647\u0645 \u0639\u0646 65 \u0639\u0627\u0645\u064b\u0627 \u0644\u062f\u064a\u0647\u0645 \u0645\u062c\u0645\u0648\u0639\u0629 \u0648\u0627\u0633\u0639\u0629 \u0645\u0646 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621 \u0648\u0627\u0644\u0628\u064a\u0636\u0627\u0621 \u064a\u0646\u062a\u062c\u0647\u0627 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0645\u0646 20.000 \u0625\u0644\u0649 200000 \u0646\u0648\u0639 \u0645\u062e\u062a\u0644\u0641 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0641\u064a \u0646\u062e\u0627\u0639 \u0627\u0644\u0639\u0638\u0627\u0645.<\/p>\n

\u0641\u064a \u0627\u0644\u0630\u064a\u0646 \u062a\u0632\u064a\u062f \u0623\u0639\u0645\u0627\u0631\u0647\u0645 \u0639\u0646 65 \u0639\u0627\u0645\u064b\u0627\u060c \u0643\u0627\u0646\u062a \u0627\u0644\u0635\u0648\u0631\u0629 \u0645\u062e\u062a\u0644\u0641\u0629 \u062a\u0645\u0627\u0645\u064b\u0627. \u062c\u0627\u0621 \u062d\u0648\u0627\u0644\u064a \u0646\u0635\u0641 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0644\u062f\u064a\u0647\u0645 \u0645\u0646 10 \u0623\u0648 20 \u062e\u0644\u064a\u0629 \u062c\u0630\u0639\u064a\u0629 \u0645\u062a\u0645\u064a\u0632\u0629\u060c \u0645\u0645\u0627 \u0623\u062f\u0649 \u0625\u0644\u0649 \u062a\u0642\u0644\u064a\u0644 \u062a\u0646\u0648\u0639 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0644\u062f\u0649 \u0627\u0644\u0634\u062e\u0635 \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631\u060c \u0645\u0639 \u0645\u0627 \u064a\u062a\u0631\u062a\u0628 \u0639\u0644\u0649 \u0630\u0644\u0643 \u0645\u0646 \u0639\u0648\u0627\u0642\u0628 \u0639\u0644\u0649 \u0635\u062d\u062a\u0647\u0645.<\/p>\n

\u0643\u062a\u0628 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a \u062f\u0648\u0631\u064a\u0629 \u0646\u064a\u062a\u0634\u0631\u060c \u0623\u0648\u0636\u062d\u0648\u0627 \u0623\u0646\u0647 \u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0645\u062a\u0648\u0631\u0637\u0629 \u0641\u064a \u062c\u0639\u0644 \u0627\u0644\u062f\u0645 \u064a\u062c\u0645\u0639 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0628\u0645\u0631\u0648\u0631 \u0627\u0644\u0648\u0642\u062a\u060c \u0641\u0625\u0646 \u0645\u0639\u0638\u0645 \u0647\u0630\u0647 \u0627\u0644\u062a\u063a\u064a\u064a\u0631\u0627\u062a \u063a\u064a\u0631 \u0636\u0627\u0631\u0629. \u0648\u0644\u0643\u0646 \u062a\u0638\u0647\u0631 \u0627\u0644\u0645\u0634\u0643\u0644\u0627\u062a \u0639\u0646\u062f\u0645\u0627 \u062a\u062c\u0639\u0644 \u0627\u0644\u0637\u0641\u0631\u0627\u062a “\u0627\u0644\u062f\u0627\u0641\u0639\u0629” \u0627\u0644\u0646\u0627\u062f\u0631\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u062a\u0646\u0645\u0648 \u0628\u0634\u0643\u0644 \u0623\u0633\u0631\u0639\u060c \u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u062a\u0646\u062a\u062c \u062e\u0644\u0627\u064a\u0627 \u062f\u0645 \u0645\u0646\u062e\u0641\u0636\u0629 \u0627\u0644\u062c\u0648\u062f\u0629 \u0643\u0645\u0642\u0627\u064a\u0636\u0629.<\/p>\n

\u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u0648\u0646 \u0627\u0644\u0634\u062e\u0635 \u0641\u064a \u0627\u0644\u062b\u0644\u0627\u062b\u064a\u0646\u064a\u0627\u062a \u0648\u0627\u0644\u0623\u0631\u0628\u0639\u064a\u0646\u064a\u0627\u062a \u0645\u0646 \u0627\u0644\u0639\u0645\u0631\u060c \u0641\u0625\u0646 \u0645\u064a\u0632\u0629 \u0646\u0645\u0648 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0634\u0627\u0630\u0629 \u062a\u062d\u062f\u062b \u0641\u0631\u0642\u064b\u0627 \u0628\u0633\u064a\u0637\u064b\u0627\u060c \u0648\u0644\u0643\u0646 \u0641\u064a \u0633\u0646 \u0627\u0644\u0633\u0628\u0639\u064a\u0646 \u0648\u0623\u0643\u062b\u0631\u060c \u062a\u0647\u064a\u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0633\u0631\u064a\u0639\u0629 \u0627\u0644\u0646\u0645\u0648 \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645.<\/p>\n

\u0642\u0627\u0644 \u0643\u0627\u0645\u0628\u0644: “\u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u0647\u0627\u0626\u0644 \u064a\u0641\u0633\u0631 \u0633\u0628\u0628 \u062d\u062f\u0648\u062b \u0645\u062b\u0644 \u0647\u0630\u0627 \u0627\u0644\u062a\u063a\u064a\u064a\u0631 \u0627\u0644\u0645\u0641\u0627\u062c\u0626 \u0641\u064a \u0627\u0644\u0636\u0639\u0641 \u0628\u0639\u062f \u0633\u0646 \u0627\u0644\u0633\u0628\u0639\u064a\u0646\u060c \u0648\u0644\u0645\u0627\u0630\u0627 \u064a\u0635\u064a\u0628 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0647\u0630\u0627 \u0627\u0644\u0646\u0648\u0639 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631”. \u062a\u0631\u062a\u0628\u0637 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0633\u0631\u064a\u0639\u0629 \u0627\u0644\u0646\u0645\u0648 \u0628\u0633\u0631\u0637\u0627\u0646\u0627\u062a \u0627\u0644\u062f\u0645 \u0648\u0641\u0642\u0631 \u0627\u0644\u062f\u0645\u060c \u0648\u0644\u0643\u0646\u0647\u0627 \u0623\u064a\u0636\u064b\u0627 \u062a\u062c\u0639\u0644 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0623\u0642\u0644 \u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u062d\u0645\u0644 \u0627\u0644\u0639\u062f\u0648\u0649 \u0648\u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0645\u062b\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a.<\/p>\n

\u0648\u0623\u0636\u0627\u0641 \u0643\u0627\u0645\u0628\u0644: “\u0645\u0627 \u0646\u0639\u0631\u0641\u0647 \u0639\u0646 \u0623\u0646\u0638\u0645\u0629 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0623\u062e\u0631\u0649 \u0647\u0648 \u0623\u0646 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0644\u0627\u062d\u0638\u0627\u062a \u0646\u0641\u0633\u0647\u0627 \u062a\u0646\u0637\u0628\u0642” \u060c \u062d\u064a\u062b \u064a\u0639\u062a\u0632\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0627\u0644\u0622\u0646 \u0627\u0644\u0628\u062d\u062b \u0639\u0646 \u0646\u0641\u0633 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0641\u064a \u0627\u0644\u062c\u0644\u062f \u0644\u0641\u0647\u0645 \u0633\u0628\u0628 \u062a\u0633\u0628\u0628 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0641\u064a \u0638\u0647\u0648\u0631 \u0627\u0644\u062a\u062c\u0627\u0639\u064a\u062f \u0648\u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u062a\u0626\u0627\u0645 \u0627\u0644\u062c\u0631\u0648\u062d.<\/p>\n

\u0642\u0627\u0644\u062a \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0629 \u0625\u0644\u064a\u0633\u0627 \u0644\u0648\u0631\u064a\u0646\u062a\u064a\u060c \u0627\u0644\u0623\u0633\u062a\u0627\u0630\u0629 \u0627\u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0641\u064a \u0645\u0639\u0647\u062f \u0648\u064a\u0644\u0643\u0648\u0645- \u0625\u0645 \u0622\u0631 \u0633\u064a \u0643\u0627\u0645\u0628\u0631\u064a\u062f\u062c \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0648\u0627\u0644\u0628\u0627\u062d\u062b\u0629 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0627\u0644\u0645\u0634\u062a\u0631\u0643\u0629 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u0625\u0646 \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0632\u0645\u0646\u0629 \u0648\u0627\u0644\u062a\u062f\u062e\u064a\u0646 \u0648\u0627\u0644\u0639\u062f\u0648\u0649 \u0648\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0646\u062a\u062c \u062c\u0645\u064a\u0639\u0647\u0627 \u062e\u0644\u0627\u064a\u0627 \u062c\u0630\u0639\u064a\u0629 \u0630\u0627\u062a \u0637\u0641\u0631\u0627\u062a \u0645\u0633\u0628\u0628\u0629 \u0644\u0644\u0633\u0631\u0637\u0627\u0646.<\/p>\n

\u0648\u0642\u0627\u0644\u062a: “\u0646\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0624\u062f\u064a \u0647\u0630\u0647 \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0623\u064a\u0636\u064b\u0627 \u0625\u0644\u0649 \u0627\u0646\u062e\u0641\u0627\u0636 \u062a\u0646\u0648\u0639 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629”. \u0645\u0646 \u0627\u0644\u0645\u0645\u0643\u0646 \u0623\u0646 \u062a\u0643\u0648\u0646 \u0647\u0646\u0627\u0643 \u0639\u0648\u0627\u0645\u0644 \u0642\u062f \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u0625\u0628\u0637\u0627\u0621 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0623\u064a\u0636\u064b\u0627. \u0644\u062f\u064a\u0646\u0627 \u0627\u0644\u0622\u0646 \u0645\u0647\u0645\u0629 \u0645\u062b\u064a\u0631\u0629 \u062a\u062a\u0645\u062b\u0644 \u0641\u064a \u0627\u0643\u062a\u0634\u0627\u0641 \u0643\u064a\u0641\u064a\u0629 \u062a\u0623\u062b\u064a\u0631 \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0645\u0643\u062a\u0634\u0641\u0629 \u062d\u062f\u064a\u062b\u064b\u0627 \u0639\u0644\u0649 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u062f\u0645 \u0644\u062f\u0649 \u0643\u0628\u0627\u0631 \u0627\u0644\u0633\u0646\u060c \u062d\u062a\u0649 \u0646\u062a\u0645\u0643\u0646 \u0645\u0646 \u062a\u0639\u0644\u0645 \u0643\u064a\u0641\u064a\u0629 \u062a\u0642\u0644\u064a\u0644 \u0645\u062e\u0627\u0637\u0631 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0648\u062a\u0639\u0632\u064a\u0632 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0635\u062d\u064a\u0629”.<\/p>\n

\u0648\u0644\u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u0639\u0648\u0627\u0645\u0644 \u0627\u0644\u062a\u064a \u062a\u0624\u0630\u064a \u0627\u0644\u0649 \u0627\u0646\u062e\u0641\u0627\u0636 \u062a\u0646\u0648\u0639 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0642\u0627\u0645 \u0627\u0644\u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0639\u0644\u0645\u0627\u0621 \u062d\u0648\u0644 \u0627\u0644\u0639\u0627\u0644\u0645 \u064a\u0627\u0644\u0645\u0642\u0627\u0628\u0644 \u0628\u0627\u0628\u062d\u0627\u062b \u0648\u062a\u062c\u0627\u0631\u0628 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u0643\u0631\u0633\u0628\u0631 (CRISPR) \u062d\u064a\u062b \u0627\u0646 \u0647\u0630\u0647 \u0627\u0644\u0623\u062f\u0627\u0629 \u062a\u0639\u062f \u0623\u062f\u0627\u0629 \u0642\u0648\u064a\u0629 \u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0648\u0645\u060c \u0645\u0645\u0627 \u064a\u0639\u0646\u064a \u0623\u0646\u0647\u0627 \u062a\u062a\u064a\u062d \u0644\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u062a\u063a\u064a\u064a\u0631 \u062a\u0633\u0644\u0633\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0628\u0633\u0647\u0648\u0644\u0629 \u0648\u062a\u0639\u062f\u064a\u0644 \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u062c\u064a\u0646.<\/p>\n

\u061b\u061b\u0648\u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u0643\u0631\u064a\u0633\u0628\u0631 (CRISPR) \u0644\u0647\u0627 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u0637\u0628\u064a\u0642\u0627\u062a \u0627\u0644\u0645\u062d\u062a\u0645\u0644\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u062a\u0635\u062d\u064a\u062d \u0627\u0644\u0639\u064a\u0648\u0628 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629\u060c \u0648\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0648\u0645\u0646\u0639 \u0627\u0646\u062a\u0634\u0627\u0631\u0647\u0627\u060c \u0648\u062a\u062d\u0633\u064a\u0646 \u0646\u0645\u0648 \u0627\u0644\u0645\u062d\u0627\u0635\u064a\u0644 \u0648\u0645\u0631\u0648\u0646\u062a\u0647\u0627. \u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0648\u0639\u0648\u062f \u0627\u0644\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0627\u060c \u0641\u0625\u0646\u0647\u0627 \u062a\u062b\u064a\u0631 \u0628\u0639\u0636 \u0627\u0644\u0645\u062e\u0627\u0648\u0641 \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a\u0629\u061b\u061b<\/strong><\/span><\/p>\n

\u0648\u0643\u0631\u064a\u0633\u0628\u0631 \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0627\u0645\u062a\u062f\u0627\u062f\u0627\u062a \u0645\u062a\u062e\u0635\u0635\u0629 \u0645\u0646 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a\u060c \u0648\u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 (Cas9) – \u062d\u064a\u062b \u064a\u0631\u0645\u0632 \u0643\u0627\u0633 \u0625\u0644\u0649 “\u0645\u0631\u062a\u0628\u0637 \u0628\u0640 CRISPR” – \u0647\u0648 \u0625\u0646\u0632\u064a\u0645 \u064a\u0639\u0645\u0644 \u0645\u062b\u0644 \u0632\u0648\u062c \u0645\u0646 \u0627\u0644\u0645\u0642\u0635 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u060c \u0627\u0644\u0642\u0627\u062f\u0631 \u0639\u0644\u0649 \u0642\u0637\u0639 \u062e\u064a\u0648\u0637 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a.<\/p>\n

\u062a\u0645 \u062a\u0643\u064a\u064a\u0641 \u062a\u0642\u0646\u064a\u0629 \u0643\u0631\u064a\u0633\u0628\u0631 \u0645\u0646 \u0622\u0644\u064a\u0627\u062a \u0627\u0644\u062f\u0641\u0627\u0639 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0644\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627 \u0648\u0627\u0644\u0639\u062a\u0627\u0626\u0642\u060c \u0648\u0647\u0648 \u0645\u062c\u0627\u0644 \u0645\u0646 \u0627\u0644\u0643\u0627\u0626\u0646\u0627\u062a \u0627\u0644\u062d\u064a\u0629 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0623\u062d\u0627\u062f\u064a\u0629 \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0628\u0633\u064a\u0637\u0629 \u0646\u0633\u0628\u064a\u064b\u0627 \u0648\u062a\u0633\u062a\u062e\u062f\u0645 \u0647\u0630\u0647 \u0627\u0644\u0643\u0627\u0626\u0646\u0627\u062a (RNA) \u0627\u0644\u0645\u0634\u062a\u0642 \u0645\u0646 (CRISPR) \u060c \u0648\u0647\u0648 \u0627\u0628\u0646 \u0639\u0645 \u062c\u0632\u064a\u0626\u064a \u0644\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a\u060c \u0648\u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a (Cas) \u0644\u0625\u062d\u0628\u0627\u0637 \u0647\u062c\u0645\u0627\u062a \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a.<\/p>\n

\u0644\u0625\u062d\u0628\u0627\u0637 \u0627\u0644\u0647\u062c\u0645\u0627\u062a\u060c \u062a\u0642\u0648\u0645 \u0627\u0644\u0643\u0627\u0626\u0646\u0627\u062a \u0627\u0644\u062d\u064a\u0629 \u0628\u062a\u0642\u0637\u064a\u0639 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0644\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u062b\u0645 \u062a\u062e\u0632\u064a\u0646 \u0623\u062c\u0632\u0627\u0621 \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0648\u0645 \u0627\u0644\u062e\u0627\u0635 \u0628\u0647\u0627\u060c \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647\u0627 \u0643\u0633\u0644\u0627\u062d \u0636\u062f \u0627\u0644\u063a\u0632\u0627\u0629 \u0627\u0644\u0623\u062c\u0627\u0646\u0628 \u0641\u064a \u062d\u0627\u0644\u0629 \u0647\u062c\u0648\u0645 \u062a\u0644\u0643 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0645\u0631\u0629 \u0623\u062e\u0631\u0649.<\/p>\n

\u0639\u0646\u062f\u0645\u0627 \u064a\u062a\u0645 \u0646\u0642\u0644 \u0645\u0643\u0648\u0646\u0627\u062a \u0643\u0631\u064a\u0633\u0628\u0631 \u0625\u0644\u0649 \u0643\u0627\u0626\u0646\u0627\u062a \u0623\u062e\u0631\u0649 \u0623\u0643\u062b\u0631 \u062a\u0639\u0642\u064a\u062f\u064b\u0627\u060c \u064a\u0645\u0643\u0646 \u0644\u0647\u0630\u0647 \u0627\u0644\u0645\u0643\u0648\u0646\u0627\u062a \u0628\u0639\u062f \u0630\u0644\u0643 \u0645\u0639\u0627\u0644\u062c\u0629 \u0627\u0644\u062c\u064a\u0646\u0627\u062a\u060c \u0648\u0647\u064a \u0639\u0645\u0644\u064a\u0629 \u062a\u0633\u0645\u0649 “\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0627\u062a”.<\/p>\n

\"\"
\u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u062c\u0632\u064a\u0621 \u0645\u0632\u062f\u0648\u062c \u062a\u0642\u0637\u0639\u062a \u0628\u0647 \u0627\u0644\u0633\u0628\u0644 \u0648\u062a\u062a\u0643\u0648\u0646 “\u062f\u0631\u062c\u0627\u062a\u0647” \u0645\u0646 \u0632\u0648\u062c \u0645\u0646 \u0627\u062b\u0646\u064a\u0646 \u0645\u0646 \u0627\u0644\u0623\u0632\u0648\u0627\u062c \u0627\u0644\u0642\u0627\u0639\u062f\u064a\u0629: \u0627\u0644\u0623\u062f\u064a\u0646\u064a\u0646 \u0627\u0644\u0645\u0642\u062a\u0631\u0646 \u0628\u0627\u0644\u062b\u064a\u0645\u064a\u0646 \u0623\u0648 \u0627\u0644\u0633\u064a\u062a\u0648\u0632\u064a\u0646 \u0627\u0644\u0645\u0642\u062a\u0631\u0646 \u0628\u0627\u0644\u062c\u0648\u0627\u0646\u064a\u0646. (\u0631\u0635\u064a\u062f \u0627\u0644\u0635\u0648\u0631\u0629: Shutterstock).<\/span><\/figcaption><\/figure>\n

\u0648\u0645\u0646 \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0639\u0644\u0645\u0627\u0621 \u0627\u0644\u0630\u064a\u0646 \u0627\u062c\u0631\u0648\u0627 \u0623\u0628\u062d\u0627\u062b \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0647\u0630\u0647 \u0627\u0644\u062a\u0642\u0646\u064a\u0629\u060c \u0627\u0644\u0639\u0627\u0644\u0645 \u0627\u0644\u0635\u064a\u0646\u064a \u0648\u0627\u0646\u062c \u0648\u0632\u0645\u0644\u0627\u0626\u0647 \u0645\u0646 \u0627\u0644\u0623\u0643\u0627\u062f\u064a\u0645\u064a\u0629 \u0627\u0644\u0635\u064a\u0646\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0641\u064a \u0628\u0643\u064a\u0646 \u0648\u0646\u0634\u0631\u062a \u0647\u0630\u0647 \u0627\u0644\u0627\u0628\u062d\u0627\u062b \u0641\u064a \u0645\u062c\u0644\u0629 (Science Translational Medicine) \u062d\u064a\u062b \u0623\u062c\u0631\u0649 \u0648\u0627\u0646\u062c \u0648\u0622\u062e\u0631\u0648\u0646 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 \u0627\u0644\u062c\u064a\u0646\u0648\u0645 \u0639\u0644\u0649 \u0623\u0633\u0627\u0633 (CRISPR-Cas9) \u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629.<\/p>\n

\u062d\u062f\u062f\u0648\u0627 (KAT7) \u0643\u0645\u062d\u0631\u0643 \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u0628\u0627\u0644\u063a\u0629 \u0648\u0623\u062f\u0649 \u0625\u0628\u0637\u0627\u0644 \u0645\u0641\u0639\u0648\u0644 (KAT7) \u0625\u0644\u0649 \u062a\u062c\u062f\u064a\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u0628\u0631\u0648\u062c\u0631\u0648\u064a\u062f\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0642\u062f\u0645\u062a \u0641\u064a \u0627\u0644\u0633\u0646 \u0642\u0628\u0644 \u0627\u0644\u0623\u0648\u0627\u0646\u060c \u0643\u0645\u0627 \u0623\u062f\u0649 \u0625\u0644\u0649 \u0625\u0637\u0627\u0644\u0629 \u0639\u0645\u0631 \u0627\u0644\u0641\u0626\u0631\u0627\u0646.<\/p>\n

\u0628\u064a\u0646\u0645\u0627 \u0645\u0646 \u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0623\u0646 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 (\u062d\u0627\u0644\u0629 \u062a\u0648\u0642\u0641 \u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u062f\u0627\u0626\u0645) \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u0642\u062f\u0645 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629\u060c \u0641\u0625\u0646 \u0643\u064a\u0641\u064a\u0629 \u062d\u062f\u0648\u062b \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u0644\u0627 \u062a\u0632\u0627\u0644 \u063a\u064a\u0631 \u0648\u0627\u0636\u062d\u0629. \u0625\u0646 \u0641\u0647\u0645\u0646\u0627 \u0644\u0645\u0627 \u064a\u062d\u0631\u0643 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0645\u0641\u064a\u062f \u0641\u064a \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u062a\u062f\u062e\u0644\u0627\u062a \u0644\u062a\u0639\u0632\u064a\u0632 \u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0637\u0648\u0644 \u0627\u0644\u0639\u0645\u0631.<\/p>\n

\u0639\u0646\u062f\u0645\u0627 \u0646\u0634\u0631 \u0648\u0627\u0646\u063a \u0648\u0632\u0645\u0644\u0627\u0624\u0647 \u0645\u0646 \u0627\u0644\u0623\u0643\u0627\u062f\u064a\u0645\u064a\u0629 \u0627\u0644\u0635\u064a\u0646\u064a\u0629 \u0644\u0644\u0639\u0644\u0648\u0645 \u0641\u064a \u0628\u0643\u064a\u0646 \u0645\u0642\u0627\u0644\u0627\u0647\u0645 \u0641\u064a \u0645\u062c\u0644\u0629\u00a0(Science Translational Medicine) \u0642\u0627\u0645\u0648\u0627 \u0641\u064a\u0647 \u0628\u0627\u0644\u062a\u0646\u0642\u064a\u0628 \u0639\u0646 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629.<\/p>\n

\u0644\u0642\u062f \u0642\u0627\u0645\u0648\u0627 \u0628\u0646\u0632\u0639 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0642\u0648\u0645 \u0628\u0646\u0645\u0630\u062c\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0623\u062f\u0627\u0629 \u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0643\u0631\u064a\u0633\u0628\u0631 \u0644\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u064a\u0624\u062f\u064a \u0646\u0642\u0635\u0647\u0627 \u0625\u0644\u0649 \u062a\u062e\u0641\u064a\u0641 \u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0648 \u0623\u0646\u062a\u062c\u062a \u0647\u0630\u0647 \u0627\u0644\u0634\u0627\u0634\u0629 (KAT7) \u060c \u0648\u0627\u0644\u062a\u064a \u060c \u0639\u0646\u062f \u062a\u0639\u0637\u064a\u0644\u0647\u0627 \u060c \u0623\u062f\u062a \u0625\u0644\u0649 \u062a\u062c\u062f\u064a\u062f \u0634\u0628\u0627\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0642\u062f\u0645\u062a \u0641\u064a \u0627\u0644\u0639\u0645\u0631 \u0642\u0628\u0644 \u0627\u0644\u0623\u0648\u0627\u0646. \u0639\u0646\u062f\u0645\u0627 \u0639\u0637\u0644\u0648\u0627 (KAT7) \u0641\u064a \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u062a\u064a \u062a\u0642\u062f\u0645\u062a \u0641\u064a \u0627\u0644\u0639\u0645\u0631 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a \u0648\u0645\u0628\u0643\u0631\u060c \u062a\u0645 \u0625\u0637\u0627\u0644\u0629 \u0639\u0645\u0631 \u0627\u0644\u0642\u0648\u0627\u0631\u0636\u064a\u0646.<\/p>\n

\u0648 \u062d\u064a\u062b \u062a\u0631\u0643\u0632 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0644\u0649 (KAT7) \u0643\u0647\u062f\u0641 \u0639\u0644\u0627\u062c\u064a \u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u062a\u062f\u062e\u0644\u0627\u062a \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u062d\u064a\u062b \u0627\u062b\u0628\u062a\u062a \u0648\u0628\u0627\u0644\u062f\u0644\u064a\u0644 \u0639\u0644\u0649 \u0623\u0646\u0647 \u064a\u0645\u0643\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0643\u0631\u064a\u0633\u0628\u0631 \u0644\u062a\u0639\u0632\u064a\u0632 \u0637\u0648\u0644 \u0627\u0644\u0639\u0645\u0631.<\/p>\n

\u0642\u0627\u0644 \u0627\u0644\u0645\u0624\u0644\u0641\u0648\u0646 \u0641\u064a \u0645\u0642\u0627\u0644\u0647\u0645: “\u062a\u0636\u064a\u0641 \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0645\u062b\u0627\u0644\u064b\u0627 \u0622\u062e\u0631 \u064a\u0648\u0636\u062d \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0645\u0642\u0627\u0648\u0645\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629”.<\/strong><\/p>\n

\u0625\u0628\u0637\u0627\u0621 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0639\u0646\u062f \u0627\u0644\u0628\u0634\u0631<\/strong><\/span><\/p>\n

\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0647\u064a \u0639\u0645\u0644\u064a\u0629 \u0644\u0627 \u0645\u0641\u0631 \u0645\u0646\u0647\u0627 \u0639\u0644\u0649 \u0645\u0627 \u064a\u0628\u062f\u0648 \u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u062f\u0647\u0648\u0631 \u0648\u0638\u064a\u0641\u064a \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u0643\u0627\u0626\u0646\u0627\u062a \u0627\u0644\u062d\u064a\u0629 \u062a\u0642\u0631\u064a\u0628\u064b\u0627. \u0648\u0638\u0647\u0648\u0631 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0645\u0624\u062e\u0631\u064b\u0627 \u0643\u0639\u0644\u0627\u0645\u0629 \u0645\u0645\u064a\u0632\u0629 \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0645\u062d\u0631\u0643 \u0623\u0633\u0627\u0633\u064a \u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u062d\u064a\u062b \u062a\u062a\u0631\u0627\u0643\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u0627\u0626\u062e\u0629 \u0641\u064a \u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0628\u0645\u0631\u0648\u0631 \u0627\u0644\u0648\u0642\u062a \u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u0638\u0647\u0648\u0631 \u0627\u0644\u0633\u0645\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 \u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062c\u0633\u0645 \u0648\u0627\u0644\u0645\u0633\u0627\u0647\u0645\u0629 \u0641\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0645\u062b\u0644 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0641\u0627\u0635\u0644 \u0648\u0645\u0631\u0636 \u0627\u0644\u0632\u0647\u0627\u064a\u0645\u0631.<\/p>\n

\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u0627\u0626\u062e\u0629 \u0644\u0627 \u062a\u062f\u0644 \u0641\u0642\u0637 \u0639\u0644\u0649 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629\u061b \u0628\u0644 \u062a\u0644\u0639\u0628 \u0647\u0630\u0647 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u063a\u064a\u0631 \u0627\u0644\u0645\u062a\u0643\u0627\u062b\u0631\u0629 \u062f\u0648\u0631\u064b\u0627 \u0645\u0633\u0628\u0628\u064b\u0627 \u0641\u064a \u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0643\u0627\u0626\u0646 \u0627\u0644\u062d\u064a. \u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644\u060c \u062a\u062a\u0631\u0627\u0643\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u0627\u0626\u062e\u0629 \u062a\u062f\u0631\u064a\u062c\u064a\u064b\u0627 \u0641\u064a \u0627\u0644\u0643\u0628\u062f \u0627\u0644\u0645\u062a\u062d\u0644\u0644\u060c \u0641\u064a \u062d\u064a\u0646 \u0623\u0646 \u0625\u0632\u0627\u0644\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u0627\u0626\u062e\u0629 \u0645\u0646 \u0627\u0644\u0643\u0628\u062f \u064a\u062e\u0641\u0641 \u0645\u0646 \u062a\u0637\u0648\u0631 \u0627\u0644\u062a\u0646\u0643\u0633 \u0627\u0644\u062f\u0647\u0646\u064a \u0627\u0644\u0643\u0628\u062f\u064a (\u0623\u0648 \u0645\u0631\u0636 \u0627\u0644\u0643\u0628\u062f \u0627\u0644\u062f\u0647\u0646\u064a). \u0644\u0630\u0644\u0643\u060c \u0641\u0625\u0646 \u062a\u0623\u062e\u064a\u0631 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629 \u0623\u0648 \u0639\u0643\u0633\u0647\u0627 \u0642\u062f \u064a\u0648\u0641\u0631 \u0646\u0647\u062c\u064b\u0627 \u0639\u0644\u0627\u062c\u064a\u064b\u0627 \u062c\u062f\u064a\u062f\u064b\u0627 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629.<\/p>\n

\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646\u0646\u0627 \u0623\u0635\u0628\u062d\u0646\u0627 \u0623\u0643\u062b\u0631 \u0625\u0644\u0645\u0627\u0645\u064b\u0627 \u0628\u0645\u0627 \u064a\u062d\u062f\u062b \u0644\u062c\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0645\u0639 \u062a\u0642\u062f\u0645\u0646\u0627 \u200b\u200b\u0641\u064a \u0627\u0644\u0639\u0645\u0631\u060c \u0625\u0644\u0627 \u0623\u0646 \u0645\u0639\u0638\u0645 \u0645\u0627 \u0646\u0639\u0631\u0641\u0647 \u0639\u0646 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0644\u0639\u0628 \u062f\u0648\u0631\u064b\u0627 \u0641\u064a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u064a\u0646\u0634\u0623 \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u062a\u064a \u062a\u0633\u062a\u062e\u062f\u0645 \u0643\u0627\u0626\u0646\u0627\u062a \u0646\u0645\u0648\u0630\u062c\u064a\u0629 \u0642\u0635\u064a\u0631\u0629 \u0627\u0644\u0639\u0645\u0631\u060c \u0645\u062b\u0644 \u0627\u0644\u062e\u0645\u064a\u0631\u0629 \u0648\u0627\u0644\u062f\u064a\u062f\u0627\u0646 \u0648\u0627\u0644\u0630\u0628\u0627\u0628\u060c \u0648\u0627\u0644\u0633\u0645\u0643. \u0644\u0630\u0644\u0643\u060c \u064a\u0638\u0644 \u062a\u0648\u0636\u064a\u062d \u0627\u0644\u0628\u0631\u0627\u0645\u062c \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u062d\u0643\u0645 \u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0647\u062f\u0641\u064b\u0627 \u0645\u0647\u0645\u064b\u0627.<\/p>\n

\u0634\u0627\u0634\u0629 \u062a\u062d\u062f\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0627\u0644\u0645\u062d\u0641\u0632\u0629 \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0628\u0634\u0631\u064a\u0629<\/strong><\/span><\/p>\n

\u0627\u0633\u062a\u062e\u062f\u0645 \u0648\u0627\u0646\u062c \u0648\u0632\u0645\u0644\u0627\u0624\u0647 \u0623\u062f\u0627\u0629 \u0627\u0644\u0647\u0646\u062f\u0633\u0629 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 \u0627\u0644\u0642\u0648\u064a\u0629 \u0643\u0631\u064a\u0633\u0628\u0631 \u0644\u062d\u0630\u0641 \u0623\u062c\u0632\u0627\u0621 \u0635\u063a\u064a\u0631\u0629 \u0645\u0646 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0646\u0648\u0639\u064a\u0646 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0638\u0647\u0631 \u0634\u064a\u062e\u0648\u062e\u0629 \u0645\u062a\u0633\u0627\u0631\u0639\u0629. \u062d\u0645\u0644\u062a \u0647\u0630\u0647 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0645\u0633\u0628\u0628\u0629 \u0644\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u062a\u064a \u062a\u0633\u0628\u0628 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0648\u064a\u0631\u0646\u0631 (WS) \u0648\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0647\u062a\u0634\u064a\u0646\u0633\u0648\u0646 \u062c\u064a\u0644\u0641\u0648\u0631\u062f \u0628\u0631\u0648\u062c\u064a\u0631\u064a\u0627 (HGPS). \u062d\u062f\u062f \u0641\u0631\u064a\u0642 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u062e\u0641\u0641 \u0646\u0642\u0635\u0647\u0627 \u0645\u0646 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 (KAT7)\u060c \u0627\u0644\u0630\u064a \u0627\u062d\u062a\u0644 \u0627\u0644\u0645\u0631\u062a\u0628\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0641\u064a \u0643\u0644 \u0645\u0646 \u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 (WS) \u0648 (HGPS) \u0627\u0644\u0645\u0628\u0643\u0631\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629.<\/p>\n

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(Wang et al. 2021 | Sci Transl Med) \u062a\u0639\u0637\u064a\u0644 KAT7 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0627\u062a CRISPR \u064a\u062c\u062f\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0628\u0627\u0644\u063a\u0629 \u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0648\u064a\u0631\u0646\u0631. \u0632\u0627\u062f \u0646\u0642\u0635 KAT7 (sg-KAT # 1 \u0648 sg-KAT # 2) \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631 \u0645\u0646 \u0627\u0644\u0642\u062f\u0631\u0629 \u0627\u0644\u062a\u0643\u0627\u062b\u0631\u064a\u0629 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0628\u0627\u0644\u063a\u0629 \u0627\u0644\u062a\u064a \u062a\u0634\u0643\u0644 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0648\u064a\u0631\u0646\u0631 (WS) \u062f\u0648\u0646 \u0646\u0642\u0635 KAT7 (sg-NTC) \u0625\u0644\u0649 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0646\u0645\u0648\u0630\u062c\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0645\u062a\u062d\u0648\u0644\u0629 (WT) (\u0627\u0644\u064a\u0633\u0627\u0631). \u062e\u0641\u0641 \u0646\u0642\u0635 KAT7 \u0645\u0646 \u0633\u0645\u0627\u062a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 \u0627\u0644\u0645\u062a\u0639\u062f\u062f\u0629 \u0627\u0644\u062a\u064a \u062a\u0645 \u062a\u062d\u062f\u064a\u062f\u0647\u0627 \u0633\u0627\u0628\u0642\u064b\u0627 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0628\u0627\u0644\u063a\u0629 \u0645\u0646 WS \u060c \u0643\u0645\u0627 \u064a\u062a\u0636\u062d \u0645\u0646 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062a\u0627\u0644\u064a\u0629: (1) \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0626\u0648\u064a\u0629 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u062a\u0643\u0627\u062b\u0631\u0629 (\u0625\u064a\u062c\u0627\u0628\u064a\u0629 Ki67) (\u0627\u0644\u0648\u0633\u0637) \u061b (2) \u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0646\u0633\u0628\u0629 \u0627\u0644\u0645\u0626\u0648\u064a\u0629 \u0644\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u062a\u0634\u064a\u062e\u0629 (SA-\u03b2-gal-positive) (\u064a\u0645\u064a\u0646).<\/span><\/figcaption><\/figure>\n

\u0648\u0644\u0644\u062a\u062d\u0642\u0642 \u0645\u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0646\u0642\u0635 (KAT7) \u064a\u062e\u0641\u0641 \u0645\u0646 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629\u060c \u0627\u0633\u062a\u0647\u062f\u0641 \u0648\u0627\u0646\u062c \u0648\u0632\u0645\u0644\u0627\u0624\u0647 (KAT7) \u0644\u0625\u0633\u0643\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0628\u0648\u0627\u0633\u0637\u0629 (CRISPR) \u0641\u064a (WS) \u0648 (HGPS) \u0648\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u0628\u0627\u0644\u063a\u0629 \u0627\u0644\u0645\u062a\u0643\u0627\u062b\u0631\u0629. \u0648\u062c\u062f\u0648\u0627 \u0623\u0646 \u0627\u0633\u062a\u0626\u0635\u0627\u0644 (KAT7) \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062b\u0644\u0627\u062b\u0629 \u0623\u062f\u0649 \u0625\u0644\u0649 \u062a\u062d\u0633\u064a\u0646 \u0625\u0645\u0643\u0627\u0646\u0627\u062a \u0627\u0644\u062a\u0643\u0627\u062b\u0631 \u0648\u062a\u062e\u0641\u064a\u0641 \u0645\u064a\u0632\u0627\u062a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629. \u0639\u0644\u0627\u0648\u0629 \u0639\u0644\u0649 \u0630\u0644\u0643\u060c \u0641\u0625\u0646 \u0627\u0633\u062a\u0626\u0635\u0627\u0644 (KAT7) \u064a\u062e\u0641\u0641 \u0645\u0646 \u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0645\u0646 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0648\u0627\u0644\u0623\u0634\u0639\u0629 \u0641\u0648\u0642 \u0627\u0644\u0628\u0646\u0641\u0633\u062c\u064a\u0629 \u0648\u0627\u0644\u0625\u062c\u0647\u0627\u062f \u0627\u0644\u062a\u0623\u0643\u0633\u062f\u064a. \u0648\u062a\u0634\u064a\u0631 \u0647\u0630\u0647 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0625\u0644\u0649 \u0623\u0646 \u0627\u0633\u062a\u0646\u0641\u0627\u062f (KAT7) \u064a\u062e\u0641\u0641 \u0645\u0646 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0641\u064a \u0633\u064a\u0627\u0642\u0627\u062a \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0645\u062a\u0646\u0648\u0639\u0629.<\/p>\n

\u0623\u062e\u064a\u0631\u064b\u0627\u060c \u0623\u0631\u0627\u062f \u0648\u0627\u0646\u062c \u0648\u0632\u0645\u0644\u0627\u0624\u0647 \u0627\u062e\u062a\u0628\u0627\u0631 \u0646\u0647\u062c \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0643\u0631\u064a\u0633\u0628\u0631 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0641\u064a \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u0627\u062a \u0627\u0644\u062d\u064a\u0629. \u0644\u0630\u0644\u0643\u060c \u0627\u062e\u062a\u0628\u0631 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u062a\u0623\u062b\u064a\u0631 \u062a\u0639\u0637\u064a\u0644 (KAT7) \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0643\u0631\u064a\u0633\u0628\u0631 \u0641\u064a \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u062a\u064a \u062a\u0642\u062f\u0645\u062a \u0641\u064a \u0627\u0644\u0639\u0645\u0631 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a \u0648\u0642\u0628\u0644 \u0627\u0644\u0623\u0648\u0627\u0646. \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0644\u0625\u064a\u0635\u0627\u0644 \u0645\u0643\u0648\u0646\u0627\u062a \u0643\u0631\u064a\u0633\u0628\u0631 \u0644\u062a\u0639\u0637\u064a\u0644 (KAT7) \u060c \u0639\u0646\u062f \u0625\u0639\u0637\u0627\u0626\u0647\u0627 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0648\u0631\u064a\u062f\u060c \u0631\u0623\u0649 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0623\u0646 \u0647\u0630\u0627 \u064a\u062e\u0641\u0641 \u0645\u0646 \u0634\u064a\u062e\u0648\u062e\u0629 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0643\u0628\u062f \u0648\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0643\u0628\u062f \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0625\u0637\u0627\u0644\u0629 \u0627\u0644\u0639\u0645\u0631 \u0627\u0644\u0627\u0641\u062a\u0631\u0627\u0636\u064a \u0644\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u062a\u064a \u062a\u0642\u062f\u0645\u062a \u0641\u064a \u0627\u0644\u0639\u0645\u0631 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a \u0648\u0642\u0628\u0644 \u0627\u0644\u0623\u0648\u0627\u0646.<\/p>\n

\u0648\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u062a\u0623\u062b\u064a\u0631\u0627\u062a \u0648\u0627\u0639\u062f\u0629\u060c \u0625\u0644\u0627 \u0623\u0646\u0647\u0627 \u0644\u0645 \u062a\u0638\u0647\u0631 \u0641\u064a \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0623\u062e\u0631\u0649 \u0644\u0623\u0646 \u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0648\u062c\u062f\u0648\u0627 \u0641\u0642\u0637 \u0623\u0646 \u0627\u0644\u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0640 (KAT7) \u064a\u062d\u062f\u062b \u0641\u064a \u0627\u0644\u0643\u0628\u062f \u0639\u0644\u0649 \u0627\u0644\u0623\u0631\u062c\u062d \u0628\u0633\u0628\u0628 \u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a. \u0633\u062a\u062d\u062a\u0627\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629 \u0625\u0644\u0649 \u0641\u062d\u0635 \u0646\u062a\u0627\u0626\u062c \u0627\u0633\u062a\u0647\u062f\u0627\u0641 (KAT7) \u0641\u064a \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0623\u0648 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0645\u062d\u062f\u062f\u0629 \u0644\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0648\u0638\u064a\u0641\u0629 \u0648\u0646\u0637\u0627\u0642 \u0627\u0644\u0623\u0645\u0627\u0646 \u0644\u062a\u062f\u062e\u0644 (KAT7).<\/p>\n

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(\u0648\u0627\u0646\u062c \u0648\u0622\u062e\u0631\u0648\u0646 .2021 | Sci Transl Med) \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0630\u064a \u064a\u0633\u062a\u0647\u062f\u0641 KAT7 \u064a\u0637\u064a\u0644 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0635\u062d\u064a \u0648\u0627\u0644\u0639\u0645\u0631 \u0627\u0644\u0627\u0641\u062a\u0631\u0627\u0636\u064a \u0644\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0633\u0646\u0629 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a. \u0645\u0646\u062d\u0646\u0649 \u0627\u0644\u0628\u0642\u0627\u0621 \u0639\u0644\u0649 \u0642\u064a\u062f \u0627\u0644\u062d\u064a\u0627\u0629 (\u064a\u0633\u0627\u0631) \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u062d\u0627\u0645\u0644\u0629 \u0644\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a CRISPR \u0627\u0644\u062a\u064a \u062a\u0633\u062a\u0647\u062f\u0641 \u0645\u0643\u0648\u0646\u0627\u062a KAT7 (sg-Kat7 \u061b \u0623\u062e\u0636\u0631) \u0623\u0648 DNA \u063a\u064a\u0631 \u0645\u062d\u062f\u062f (sg-NTC \u061b \u0631\u0645\u0627\u062f\u064a) \u0639\u0646\u062f 20 \u0634\u0647\u0631\u064b\u0627. \u0645\u0646\u062d\u0646\u0649 \u0627\u0644\u0628\u0642\u0627\u0621 \u0639\u0644\u0649 \u0642\u064a\u062f \u0627\u0644\u062d\u064a\u0627\u0629 (\u064a\u0645\u064a\u0646) \u0645\u0646 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 (Zmpste24 – \/ -) \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u0645\u0643\u0648\u0646\u0627\u062a \u0643\u0631\u064a\u0633\u0628\u0631 \u0627\u0644\u062a\u064a \u062a\u0633\u062a\u0647\u062f\u0641 \u0641\u064a\u0631\u0648\u0633 KAT7 (sg-Kat7) \u0623\u0648 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u063a\u064a\u0631 \u0627\u0644\u0646\u0648\u0639\u064a (sg-NTC).<\/span><\/figcaption><\/figure>\n

\u0647\u0644 \u064a\u0645\u0643\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0643\u0631\u064a\u0633\u0628\u0631 \u0643\u0639\u0644\u0627\u062c \u0645\u0636\u0627\u062f \u0644\u0644\u0634\u064a\u062e\u0648\u062e\u0629\u061f<\/strong><\/span><\/p>\n

“\u062a\u0636\u064a\u0641 \u062f\u0631\u0627\u0633\u062a\u0646\u0627 \u0637\u0628\u0642\u0629 \u0645\u0646 \u0627\u0644\u062a\u0639\u0642\u064a\u062f \u0625\u0644\u0649 \u0648\u0638\u064a\u0641\u0629 (KAT7) \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u0643\u0634\u0641 \u0639\u0646 \u062f\u0648\u0631\u0647\u0627 \u0627\u0644\u0645\u0647\u0645 \u0641\u064a \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u062a\u062d\u062f\u064a\u062f (KAT7) \u0643\u0647\u062f\u0641 \u062c\u062f\u064a\u062f \u0644\u062a\u0623\u062e\u064a\u0631 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0639\u0644\u0627\u062c \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629” \u060c \u0642\u0627\u0644 \u0627\u0644\u0645\u0624\u0644\u0641\u0648\u0646 \u0641\u064a \u0627\u0644\u0645\u0642\u0627\u0644. “\u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0643\u0634\u0641 \u0639\u0646 \u062f\u0648\u0631 (KAT7) \u0641\u064a \u0627\u0644\u062a\u0648\u0633\u0637 \u0641\u064a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629\u060c \u062d\u062f\u062f\u062a \u0634\u0627\u0634\u062a\u0646\u0627 \u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0627\u0644\u0625\u0636\u0627\u0641\u064a\u0629 \u0627\u0644\u062a\u064a \u0642\u062f \u062a\u0633\u062a\u0647\u062f\u0641 \u062a\u062d\u0633\u064a\u0646 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629”.<\/p>\n

\u0639\u0644\u0627\u0648\u0629 \u0639\u0644\u0649 \u0630\u0644\u0643\u060c \u062a\u064f\u0638\u0647\u0631 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0646 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0645\u0633\u062a\u0646\u062f \u0625\u0644\u0649 (CRISPR) \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0639\u0637\u0644 \u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0645\u062b\u0644 (KAT7) \u0644\u062a\u062c\u062f\u064a\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629. \u0648\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0644\u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0627\u0639\u062f\u0629\u060c \u0625\u0644\u0627 \u0623\u0646\u0647 \u0645\u0646 \u0627\u0644\u0633\u0627\u0628\u0642 \u0644\u0623\u0648\u0627\u0646\u0647 \u0645\u0639\u0631\u0641\u0629 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0643\u0631\u064a\u0633\u0628\u0631 \u0633\u062a\u0643\u0648\u0646 \u0641\u0639\u0627\u0644\u0629 \u0641\u064a \u0627\u0644\u0628\u0634\u0631 \u0644\u062a\u062d\u0633\u064a\u0646 \u0641\u062a\u0631\u0629 \u0627\u0644\u0635\u062d\u0629 \u0648\u0637\u0648\u0644 \u0627\u0644\u0639\u0645\u0631.<\/p>\n

\u0627\u0644\u0645\u0635\u0627\u062f\u0631:<\/strong><\/p>\n

    \n
  1. https:\/\/www.theguardian.com\/science\/2022\/jun\/01\/research-may-reveal-why-people-can-suddenly-become-frail-in-their-70s<\/strong><\/a><\/li>\n
  2. https:\/\/www.bayshore.ca\/2018\/09\/20\/the-physical-changes-of-aging<\/strong>\/<\/strong><\/a><\/li>\n
  3. https:\/\/nypost.com\/2019\/03\/02\/science-has-figured-out-how-to-freeze-the-aging-process<\/strong>\/<\/strong><\/li>\n
  4. https:\/\/www.synthego.com\/blog\/can-crispr-stop-us-from-aging<\/strong><\/a><\/li>\n
  5. https:\/\/createdigital.org.au\/crispr-turn-back-clock-ageing<\/strong>\/<\/strong><\/a><\/li>\n<\/ol>\n

    \u00a0<\/strong><\/p>\n

    \u00a0<\/strong><\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    \u062a\u0639\u0631\u0641 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0639\u0644\u0649 \u0623\u0646\u0647\u0627 \u0627\u0644\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u0645\u0631\u0629 \u0648\u0627\u0644\u062a\u062f\u0631\u064a\u062c\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0637\u0631\u0623 \u0639\u0644\u0649 \u0627\u0644\u062c\u0633\u062f \u0627\u0639\u062a\u0628\u0627\u0631\u064b\u0627 \u0645\u0646 \u0628\u062f\u0627\u064a\u0627\u062a \u0627\u0644\u0628\u0644\u0648\u063a \u062d\u064a\u062b \u062a\u0628\u062f\u0623 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u062c\u0633\u0645 \u0628\u0627\u0644\u062a\u0631\u0627\u062c\u0639 \u0641\u064a \u0628\u062f\u0627\u064a\u0627\u062a \u0645\u0646\u062a\u0635\u0641 \u0627\u0644\u0639\u0645\u0631 \u0648\u0647\u064a \u062d\u0642\u064a\u0642\u0629 \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0644\u0647\u0627 \u0637\u0631\u064a\u0642\u062a\u0647\u0627 \u0627\u0644\u0645\u0639\u064a\u0646\u0629 \u0641\u064a \u0627\u0644\u062d\u062f\u0648\u062b \u062e\u0627\u0631\u062c \u0646\u0637\u0627\u0642 \u0627\u0644\u062a\u062d\u0643\u0645 \u0627\u0644\u0628\u0634\u0631\u064a \u0641\u0644\u0627 \u064a\u0648\u062c\u062f \u0633\u0646 \u0645\u062d\u062f\u062f \u064a\u0645\u0643\u0646 \u0627\u0639\u062a\u0628\u0627\u0631\u0647 \u0633\u0646 \u0627\u0644\u062f\u062e\u0648\u0644 \u0641\u064a \u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0648\u0644\u0643\u0646\u060c \u062c\u0631\u0649 \u0627\u0644\u062a\u0639\u0627\u0631\u0641 \u0639\u0644\u0649 \u0623\u0646 …<\/p>\n","protected":false},"author":4,"featured_media":15640,"comment_status":"open","ping_status":"open","sticky":false,"template":"single\/single-cat-Article.php","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[15],"tags":[],"class_list":["post-16428","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-15"],"_links":{"self":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/16428","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=16428"}],"version-history":[{"count":4,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/16428\/revisions"}],"predecessor-version":[{"id":16436,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/16428\/revisions\/16436"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/media\/15640"}],"wp:attachment":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=16428"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=16428"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=16428"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}