{"id":16038,"date":"2022-05-03T01:20:06","date_gmt":"2022-05-02T22:20:06","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=16038"},"modified":"2022-05-03T01:20:06","modified_gmt":"2022-05-02T22:20:06","slug":"%d8%a3%d8%af%d9%84%d8%a9-%d8%ac%d8%af%d9%8a%d8%af%d8%a9-%d8%b9%d9%84%d9%89-%d9%83%d9%8a%d9%81-%d9%8a%d9%85%d9%83%d9%86-%d9%84%d9%84%d8%aa%d9%85%d8%a7%d8%b1%d9%8a%d9%86-%d8%a7%d9%84%d8%b1%d9%8a%d8%a7","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=16038","title":{"rendered":"\u0623\u062f\u0644\u0629 \u062c\u062f\u064a\u062f\u0629 \u0639\u0644\u0649 \u0643\u064a\u0641 \u064a\u0645\u0643\u0646 \u0644\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u0631\u064a\u0627\u0636\u064a\u0629 \u0623\u0646 \u062a\u0642\u064a \u0645\u0646 \u0623\u0636\u0631\u0627\u0631 \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a – \u062a\u0631\u062c\u0645\u0629 \u0639\u062f\u0646\u0627\u0646 \u0623\u062d\u0645\u062f \u0627\u0644\u062d\u0627\u062c\u064a"},"content":{"rendered":"

New evidence of how exercise can counter diabetes damage
\n(\u0628\u0642\u0644\u0645: \u062a\u0648\u0646\u064a \u0628\u064a\u0643\u0631 – Toni Baker)<\/span><\/h3>\n

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\"\"<\/p>\n

\u062a\u0648\u0644\u0651\u064f\u062f \/ \u062a\u0643\u0648\u0651\u0650\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 (angiogenesis1<\/sup>) \u0648\u0647\u064a \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u0643\u0648\u064a\u0646 \u0623\u0648\u0639\u064a\u0629 \u062f\u0645\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629\u060c \u0648\u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a \u0644\u0627 \u064a\u062a\u0633\u0628\u0628 \u0641\u064a \u0625\u062a\u0644\u0627\u0641 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u062d\u0633\u0628\u060c \u0628\u0644 \u064a\u0639\u064a\u0642 \u0647\u0630\u0647 \u0627\u0644\u0642\u062f\u0631\u0629 \u0627\u0644\u0641\u0637\u0631\u064a\u0629 \/ \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 \u0639\u0644\u0649 \u062a\u0643\u0648\u064a\u0646 \u0623\u0648\u0639\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0641\u064a \u0645\u0648\u0627\u062c\u0647\u0629 \u0627\u0644\u0623\u0645\u0631\u0627\u0636\u060c \u0643\u0645\u0627 \u064a\u0642\u0648\u0644 \u062e\u0628\u0631\u0627\u0621 \u0641\u064a \u0645\u0631\u0643\u0632 \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u0623\u0648\u063a\u0648\u0633\u062a\u0627 (Augusta) \u0641\u064a \u062c\u0648\u0631\u062c\u064a\u0627.<\/p>\n

\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u062a\u0628\u0637\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0647\u064a \u0639\u0645\u0644\u064a\u0629 \u0636\u0631\u0648\u0631\u064a\u0629 \u0644\u0646\u0645\u0648 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u062c\u062f\u064a\u062f\u0629.<\/p>\n

\u062d\u0627\u0644\u064a\u064b\u0627 \u0644\u062f\u0649 \u0628\u0627\u062d\u062b\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u0623\u0648\u063a\u0648\u0633\u062a\u0627 \u0623\u0648\u0644 \u062f\u0644\u064a\u0644 \u0639\u0644\u0649 \u0623\u0646\u0647 \u0641\u064a \u0645\u0648\u0627\u062c\u0647\u0629 \u0627\u0644\u0623\u0636\u0631\u0627\u0631 \u0627\u0644\u062a\u064a \u064a\u0633\u0628\u0628\u0647\u0627 \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0645\u0645\u0627\u0631\u0633\u0629 \u062a\u0645\u0627\u0631\u064a\u0646 \u0645\u0639\u062a\u062f\u0644\u0629 \u0627\u0644\u0634\u062f\u0629 \u062d\u062a\u0649 \u0644\u0648 \u0644\u0641\u062a\u0631\u0629 \u00a0\u0648\u0627\u062d\u062f\u0629 \u0645\u062f\u062a\u0647\u0627 45 \u062f\u0642\u064a\u0642\u0629 \u062a\u0645\u0643\u0651\u064d\u0646 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0627\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a (exosomes) (\u0627\u0646\u0638\u0631 2) \u060c \u0648\u0647\u064a \u062d\u0648\u064a\u0635\u0644\u0627\u062a \u062a\u062d\u062a \u0645\u062c\u0647\u0631\u064a\u0629 \u0645\u0644\u064a\u0626\u0629 \u0628\u0627\u0644\u0633\u0648\u0627\u0626\u0644 \u0627\u0644\u0646\u0634\u0637\u0629 \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u064b\u0627 \u060c \u0645\u0646 \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644 (ATP7A) \u0645\u0628\u0627\u0634\u0631\u0629 \u0625\u0644\u0649 \u062a\u0644\u0643 \u0627\u0644\u062e\u0644\u0627\u064a\u0627\u060c \u0648\u0627\u0644\u062a\u064a \u0628\u0625\u0645\u0643\u0627\u0646\u0647\u0627 \u0623\u0646 \u062a\u0628\u062f\u0623 \u0639\u0645\u0644\u064a\u0629 \u062a\u0648\u0644\u0651\u064f\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629\u060c \u062d\u0633\u0628\u0645\u0627 \u0623\u0641\u0627\u062f \u0628\u0647 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a \u0645\u062c\u0644\u0629 \u0627\u062a\u062d\u0627\u062f \u0627\u0644\u062c\u0645\u0639\u064a\u0627\u062a \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a \u0644\u0639\u0644\u0645 \u0627\u0644\u0623\u062d\u064a\u0627\u0621 \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a (FASEB3<\/sup>).<\/p>\n

\u0647\u0646\u0627\u0643 \u0634\u0628\u0647 \u0628\u064a\u0646\u0647\u0627 \u0648\u0628\u064a\u0646 \u062e\u062f\u0645\u0627\u062a \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0623\u0643\u062b\u0631 \u062a\u0637\u0648\u0631\u0627\u064b \u0648\u0643\u0641\u0627\u0621\u0629\u064b \u0648\u0627\u0644\u062a\u064a \u0646\u0639\u062a\u0645\u062f \u0639\u0644\u064a\u0647\u0627 \u062c\u0645\u064a\u0639\u064b\u0627\u060c \u0644\u0627 \u0633\u064a\u0645\u0627 \u062e\u0644\u0627\u0644 \u0627\u0644\u062c\u0627\u0626\u062d\u0629\u060c \u0641\u0625\u0646 \u0645\u0627 \u062a\u062d\u0645\u0644\u0647 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a (exosomes) \u0645\u0646 \u0633\u0648\u0627\u0626\u0644 \u064a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0645\u0646 \u0623\u064a\u0646 \u0623\u062a\u062a \u0648\u0625\u0644\u0649 \u0623\u064a\u0646 \u062a\u062a\u062c\u0647\u060c \u0643\u0645\u0627 \u064a\u0642\u0648\u0644 \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u062a\u0648\u0631\u0648 \u0641\u0648\u0643\u0627\u064a \u00a0(Tohru Fuka<\/a>) \u060c \u0627\u062e\u0635\u0627\u0626\u064a \u0628\u064a\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0623\u062e\u0635\u0627\u0626\u064a \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u0637\u0628 \u0641\u064a \u062c\u0627\u0645\u0639\u0629 \u063a\u0648\u0633\u062a\u0627 (MCG).<\/p>\n

\u064a\u0642\u0648\u0644 \u0641\u0648\u0643\u0627\u064a \u0625\u0646\u0647 \u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646\u0647 \u0648\u0627\u0644\u0645\u0624\u0644\u0641 \u0627\u0644\u0645\u0634\u0627\u0631\u0643 \u0641\u064a \u0639\u0644\u0645 \u0627\u0644\u0623\u062d\u064a\u0627\u0621 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0641\u064a \u0627\u0644\u0643\u0644\u064a\u0629 \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0645\u0627\u0633\u0648\u0643\u0648 \u0623\u0648\u0634\u064a\u0648-\u0641\u0648\u0643\u0627\u064a (Masuko Ushio-Fukai) \u0644\u0645 \u064a\u062a\u0623\u0643\u062f\u0627 \u0628\u0639\u062f \u0639\u0646 \u0623\u0635\u0644 \u0647\u0630\u0647 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0644\u0646\u0627\u0641\u0639\u0629\u060c \u0641\u0645\u0646 \u0627\u0644\u0648\u0627\u0636\u062d \u0623\u0646 \u0623\u062d\u062f \u0627\u0644\u0623\u0645\u0627\u0643\u0646 \u0627\u0644\u062a\u064a \u062a\u0648\u0635\u0644 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0644\u064a\u0647\u0627 \u0647\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629.<\/p>\n

\u0641\u064a \u0643\u0644 \u0645\u0646 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a \u0627\u0644\u0645\u0635\u0627\u0628 \u0628\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 2 \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0623\u0635\u062d\u0627\u0621 \u0645\u0645\u0646 \u064a\u0628\u0644\u063a\u0648\u0646 50 \u0639\u0627\u0645\u064b\u0627 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631\u060c \u0645\u062f\u0629 \u0623\u0633\u0628\u0648\u0639\u064a\u0646 \u0645\u0646 \u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u062c\u0631\u064a \u0639\u0644\u0649 \u0639\u062c\u0644\u0629 \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0641\u0626\u0631\u0627\u0646 \u0648\u062c\u0644\u0633\u0629 \u062a\u0645\u0631\u064a\u0646 \u062a\u062d\u0633\u064a\u0646 \u0623\u062f\u0627\u0621 \u0627\u0644\u0642\u0644\u0628 \u0644\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0645\u0646 \u0627\u0644\u0628\u0634\u0631 \u0632\u0627\u062f \u0645\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0628\u0631\u0648\u062a\u064a\u0646 (ATP7A4)<\/sup> \u0641\u064a \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0644\u0644\u0627\u0635\u0642\u0629 (binding) \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629.<\/p>\n

\u0648\u0644\u0627\u062d\u0638 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0623\u0646 \u0627\u0644\u0646\u0634\u0627\u0637 \u0641\u064a \u062a\u0644\u0643 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0644\u0645 \u064a\u0624\u062b\u0631 \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631 \u0641\u064a \u0648\u0632\u0646 \u0627\u0644\u0641\u0626\u0631\u0627\u0646\u060c \u0644\u0643\u0646\u0647 \u0632\u0627\u062f \u0623\u064a\u0636\u064b\u0627 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u0645\u0629 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0627\u0644\u062f\u0627\u0644\u0629 \u0639\u0644\u0649 \u0646\u0634\u0627\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u0648\u0639\u0648\u0627\u0645\u0644 \u0645\u062b\u0644 \u0639\u0627\u0645\u0644 \u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u0628\u0637\u0627\u0646\u064a \u0627\u0644\u0648\u0639\u0627\u0626\u064a \u0627\u0644\u0644\u0627\u0632\u0645 \u0644\u062a\u0643\u0648\u064a\u0646 \/ \u0644\u062a\u0648\u0644\u0651\u064f\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629.<\/p>\n

\u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u0628\u062f\u0646\u064a\u0629 \u0632\u0627\u062f\u062a \u0623\u064a\u0636\u064b\u0627 \u0645\u0646 \u0643\u0645\u064a\u0629 \u0627\u0646\u0632\u064a\u0645 \u0633\u0648\u0628\u0631 \u0627\u0643\u0633\u064a\u062f \u062f\u064a\u0633\u0645\u0648\u062a\u0627\u0632 (superoxide dismutase) \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0623\u0643\u0633\u062f\u0629 \u062e\u0627\u0631\u062c \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0642\u0648\u064a \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a5<\/sup>\u060c \u0623\u0648 \u0628\u0625\u062e\u062a\u0635\u0627\u0631 \u0627\u0646\u0632\u064a\u0645 (SOD36<\/sup>) \u0644\u0643\u0646\u0647\u0627 \u0627\u0644\u062d\u0645\u0648\u0644\u0629 \u0627\u0644\u0635\u0627\u0641\u064a\u0629 \u0627\u0644\u0623\u062b\u0642\u0644 \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 (ATP7A) \u060c \u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0623\u064a\u0636\u064b\u0627 \u0628\u062a\u0648\u0635\u064a\u0644 \u0639\u0646\u0635\u0631 \u0627\u0644\u0646\u062d\u0627\u0633 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0625\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627\u060c \u0648\u0647\u0630\u0627 \u0623\u0645\u0631 \u0623\u0633\u0627\u0633\u064a \u0644\u0644\u0627\u0633\u062a\u0641\u0627\u062f\u0629 \u0627\u0644\u062c\u064a\u062f\u0629 \u0645\u0646 \u0627\u0646\u0632\u064a\u0645 (SOD3) \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u060c \u0643\u0645\u0627 \u064a\u0642\u0648\u0644 \u0623\u0648\u0634\u064a\u0648 – \u0641\u0648\u0643\u0627\u064a.<\/p>\n

\u0627\u0646\u0632\u064a\u0645 (SOD3) \u060c \u0647\u0648 \u0623\u062d\u062f \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0623\u0643\u0633\u062f\u0629 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 \u0627\u0644\u0647\u0627\u0645\u0629 \u0627\u0644\u062a\u064a \u062a\u0646\u062a\u062c\u0647\u0627 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u06217<\/sup> \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0641\u064a \u062c\u062f\u0631\u0627\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0643\u0630\u0644\u0643 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0647\u064a\u0643\u0644\u064a\u06298<\/sup>\u060c \u0645\u0645\u0627 \u064a\u0633\u0627\u0639\u062f\u0646\u0627 \u0639\u0644\u0649 \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0635\u062d\u064a\u0629 \u0645\u0646 \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u064a\u06299<\/sup>\u060c \u0623\u0648 \u0627\u062e\u062a\u0635\u0627\u0631\u064b\u0627 \u062a\u0639\u0631\u0641 \u0628 (ROS). \u062a\u0639\u062f \u0627\u0644 (ROS) \u0646\u062a\u0627\u0626\u062c \u062b\u0627\u0646\u0648\u064a\u0629 \u0637\u0628\u064a\u0639\u064a\u0629 \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0646\u0627 \u0644\u0644\u0623\u0643\u0633\u062c\u064a\u0646 \u0627\u0644\u0630\u064a \u064a\u0639\u062f \u0627\u0634\u0627\u0631\u0629\u064b \u062e\u0644\u0648\u064a\u0629\u064b \u0645\u0647\u0645\u0629\u064b\u060c \u0645\u0645\u0627 \u064a\u0645\u0643\u0651\u0650\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u062a\u0646\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0648\u0638\u0627\u0626\u0641.\u00a0 \u0648\u0644\u0643\u0646 \u0628\u062f\u0644\u064b\u0627 \u0645\u0646 \u0630\u0644\u0643\u060c \u0641\u064a \u062d\u0627\u0644 \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u064a\u0624\u062f\u064a \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0633\u0643\u0631 \u0641\u064a \u0627\u0644\u062f\u0645 \u0625\u0644\u0649 \u0627\u0631\u062a\u0641\u0627\u0639 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0639\u064a\u0642 \u0627\u0644\u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629 \u0627\u0644\u0645\u0647\u0645\u0629.<\/p>\n

\u0623\u062b\u0628\u062a \u0641\u0648\u0643\u0627\u064a \u0623\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0628\u0631\u0648\u062a\u064a\u0646 (ATP7A) \u062a\u0646\u062e\u0641\u0636 \u0641\u064a \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a. \u00a0\u0644\u062f\u0649 \u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0627\u0644\u0622\u0646 \u0623\u064a\u0636\u064b\u0627 \u0628\u0639\u0636 \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0639\u0644\u0649 \u0623\u0646 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0644\u0645\u0646\u062a\u0634\u0631\u0629 \u0641\u064a \u0628\u0644\u0627\u0632\u0645\u0627 \u0627\u0644\u0646\u0645\u0627\u0630\u062c \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0646\u0634\u0637\u0629 (sedentary) \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u062f\u0627\u0621 \u0627\u0644\u0633\u0643\u0631\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 2 \u062a\u064f\u0636\u0639\u0641 \u0641\u0639\u0644\u064a\u064b\u0627 \u0645\u0646 \u0639\u0645\u0644\u064a\u0629 \u062a\u0648\u0644\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0639\u0646\u062f \u0648\u0636\u0639\u0647\u0627 \u0641\u064a \u0637\u0628\u0642 \u0641\u064a\u0647 \u062e\u0644\u0627\u064a\u0627 \u0628\u0637\u0627\u0646\u064a\u0629 \u0628\u0634\u0631\u064a\u0629\u060c \u0648\u0643\u0630\u0644\u0643 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u062d\u064a\u0648\u0627\u0646\u064a \u0644\u0627\u0644\u062a\u0626\u0627\u0645 \u0627\u0644\u062c\u0631\u0648\u062d.<\/p>\n

\u064a\u0642\u062a\u0631\u062d \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0623\u0646 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0644\u0627\u0635\u0637\u0646\u0627\u0639\u064a\u0629\u060c \u0627\u0644\u062a\u064a \u062a\u062e\u0636\u0639 \u0628\u0627\u0644\u0641\u0639\u0644 \u0644\u0644\u062f\u0631\u0627\u0633\u0629 \u0643\u0622\u0644\u064a\u0627\u062a \u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0623\u062f\u0648\u064a\u0629\u060c \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0635\u0628\u062d \u064a\u0648\u0645\u064b\u0627 \u0645\u0627 “\u0623\u0644\u064a\u0629 \u0644\u0645\u062d\u0627\u0643\u0627\u0629 \u0627\u0644\u062a\u0645\u0631\u064a\u0646\u0627\u062a” \u0644\u062a\u062d\u0633\u064a\u0646 \u0642\u062f\u0631\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0639\u0644\u0649 \u062a\u0648\u0644\u064a\u062f \u0623\u0648\u0639\u064a\u0629 \u062f\u0645\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0639\u0646\u062f\u0645\u0627 \u064a\u0636\u0631 \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a \u0628\u0642\u062f\u0631\u0627\u062a\u0647\u0645 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629.<\/p>\n

\u0641\u064a \u0627\u0644\u0648\u0627\u0642\u0639\u060c \u0644\u0642\u062f \u0642\u0627\u0645\u0648\u0627 \u0628\u0627\u0644\u0641\u0639\u0644 \u0628\u062a\u0648\u0644\u064a\u062f \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0648\u0627\u0644\u062a\u064a \u064a\u0643\u0648\u0646 \u0641\u064a\u0647\u0627 \u0627\u0646\u0632\u064a\u0645 (SOD3) \u0645\u0639\u0628\u0631\u064b\u0627 \u0628\u0634\u0643\u0644 \u0645\u0641\u0631\u0637\u00a0 (overexpressed) \u0648\u0648\u062c\u062f\u0648\u0627 \u062a\u062d\u0633\u0646\u064b\u0627 \u0641\u064a \u062a\u0648\u0644\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0648\u0627\u0644\u0634\u0641\u0627\u0621 \u0641\u064a \u0646\u0645\u0648\u0630\u062c \u0627\u0644\u0641\u0626\u0631\u0627\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0633\u0643\u0631\u064a.<\/p>\n

\u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u062a\u064a \u0645\u0646 \u0627\u0644\u0645\u0641\u062a\u0631\u0636 \u0623\u0646 \u062a\u0639\u0645\u0644 \u0628\u0647\u0627 \u0647\u064a \u0623\u0646 \u0627\u0646\u0632\u064a\u0645 (SOD3) \u064a\u064f\u0648\u0642\u0641 \u0646\u0634\u0627\u0637\u0647 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629\u060c \u0644\u0630\u0644\u0643 \u0644\u0627\u0628\u062f \u0623\u0646 \u062a\u062d\u0635\u0644 \u0639\u0644\u064a\u0647 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0623\u062e\u0631\u0649\u060c \u0643\u0645\u0627 \u064a\u0634\u064a\u0631 \u0623\u0648\u0634\u064a\u0648 – \u0641\u0648\u0643\u0627\u064a \u060c \u0648\u0645\u0646 \u0647\u0646\u0627 \u062a\u0623\u062a\u064a \u0623\u0647\u0645\u064a\u0629 \u062e\u062f\u0645\u0629 \u0627\u0644\u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u062a\u064a \u062a\u0642\u0648\u0645 \u0628\u0647\u0627 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a. \u00a0\u0644\u0627\u0628\u062f \u0623\u0646 \u064a\u0631\u062a\u0628\u0637 \u0627\u0646\u0632\u064a\u0645 (SOD3) \u0628\u0639\u062f \u0630\u0644\u0643 \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u0641\u064a \u0645\u0643\u0627\u0646\u0647\u0627 \u0627\u0644\u0637\u0628\u064a\u0639\u064a \u0627\u0644\u0645\u0633\u0645\u0649 \u0628\u0645\u062c\u0627\u0644 \u0631\u0628\u0637 \u0627\u0644\u0647\u064a\u0628\u0627\u0631\u064a\u0646 (heparin-binding domain) \u060c \u0648\u0644\u0627\u0628\u062f \u0623\u0646 \u064a\u0643\u0648\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 (ATP7A) \u0627\u0644\u0646\u0627\u0642\u0644 \u0644\u0644\u0646\u062d\u0627\u0633 \u0645\u0648\u062c\u0648\u062f\u064b\u0627 \u0644\u062a\u0645\u0643\u064a\u0646 \u0627\u0646\u0632\u064a\u0645 (SOD3) \u0645\u0646 \u0627\u0644\u0646\u0634\u0627\u0637 \u0647\u0646\u0627\u0643\u060c \u0643\u0645\u0627 \u064a\u0642\u0648\u0644 \u0641\u0648\u0643\u0627\u064a (Fukai). \u0644\u0627\u062d\u0638 \u0641\u0648\u0643\u0627\u064a \u0623\u0646 \u0643\u0644\u0627 \u0645\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 (ATP7A) \u0648\u0645\u0648\u0642\u0639 \u0627\u0644\u0631\u0628\u0637 \u0647\u0645\u0627 \u0645\u0641\u062a\u0627\u062d\u0627\u0646 \u0645\u0647\u0645\u0627\u0646 \u0644\u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629. \u00a0\u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644\u060c \u0639\u0646\u062f\u0645\u0627 \u0623\u0632\u0627\u0644\u0648\u0627 \u0645\u0648\u0642\u0639 \u0627\u0644\u0631\u0628\u0637 \u0645\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629\u060c \u0648\u0647\u0648 \u0645\u0627 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u062d\u062f\u062b \u0641\u064a \u0627\u0644\u0637\u0628\u064a\u0639\u0629\u060c \u0641\u064f\u0642\u062f\u062a \u0647\u0630\u0647 \u0627\u0644\u0641\u0648\u0627\u0626\u062f.<\/p>\n

\u0628\u0645\u062c\u0631\u062f \u0648\u0635\u0648\u0644\u0647 \u0625\u0644\u0649 \u0627\u0644\u0645\u0648\u0642\u0639 \u0646\u0634\u0637\u064b\u0627\u060c \u064a\u0642\u0648\u0645 \u0627\u0646\u0632\u064a\u0645 (SOD3) \u0628\u062a\u062d\u0648\u064a\u0644 \u0623\u0643\u0633\u064a\u062f \u0645\u0631\u0643\u0628\u0627\u062a \u0627\u0644\u0627\u0643\u0633\u062c\u064a\u0646 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u064a\u0629 \u0627\u0644\u0641\u0627\u0626\u0642\u0629 (ROS) \u0625\u0644\u0649 \u0628\u064a\u0631\u0648\u0643\u0633\u064a\u062f \u0627\u0644\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646 (H2<\/sub>O2)<\/sub>\u060c \u0648\u0647\u0648 \u0625\u0634\u0627\u0631\u0629 \u0623\u062e\u0631\u0649 \u0644\u0645\u0631\u0643\u0628\u0627\u062a (ROS) \u062a\u0633\u0627\u0639\u062f \u0641\u064a \u062f\u0639\u0645 \u0648\u0638\u064a\u0641\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629.\u00a0 \u0623\u0641\u0627\u062f \u0641\u0648\u0643\u0627\u064a \u0623\u0646\u0647 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u0627\u0644\u0628\u0634\u0631\u064a\u0629\u060c \u0627\u0644\u0625\u0641\u0631\u0627\u0637 \u0641\u064a \u062a\u0639\u0628\u064a\u0631 (overexpression) \u0627\u0646\u0632\u064a\u0645 (SOD3) \u064a\u0639\u0632\u0632 \u0645\u0646 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0630\u0644\u0643 \u0628\u0632\u064a\u0627\u062f\u0629 \u0628\u064a\u0631\u0648\u0643\u0633\u064a\u062f \u0627\u0644\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646 (H2<\/sub>O2)<\/sub>.<\/p>\n

\u062a\u0648\u0635\u064a\u0644 \u0639\u0646\u0635\u0631 \u0627\u0644\u0646\u062d\u0627\u0633 \u0645\u0633\u062a\u0645\u0631 \u0623\u064a\u0636\u064b\u0627 \u0623\u062b\u0646\u0627\u0621 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u062d\u064a\u062b \u062a\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0637\u0627\u0646\u064a\u0629 \u0628\u0627\u0646\u062a\u0638\u0627\u0645 \u0627\u0644\u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0646\u062d\u0627\u0633\u060c \u0628\u0631\u0648\u062a\u064a\u0646 (ATP7A) \u060c \u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0628\u0646\u0642\u0644\u0647 \u0644\u0644\u0645\u0639\u0627\u062f\u0646 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0627\u0644\u062a\u064a \u0646\u062a\u0627\u0648\u0644\u0647\u0627 \u0636\u0645\u0646 \u0627\u0644\u0623\u0637\u0639\u0645\u0629 \u0645\u062b\u0644 \u0627\u0644\u0645\u0643\u0633\u0631\u0627\u062a \u0648\u0627\u0644\u062d\u0628\u0648\u0628 \u0627\u0644\u0643\u0627\u0645\u0644\u0629\u060c \u064a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u0627\u0644\u0646\u062d\u0627\u0633 \u0646\u0641\u0633\u0647.<\/p>\n

\u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0627\u0644\u0628\u062f\u0646\u064a\u0629\u060c \u0643\u0627\u0644\u062c\u0631\u064a \u0623\u0648 \u0627\u0644\u0645\u0634\u064a \u0639\u0644\u0649 \u062c\u0647\u0627\u0632 \u0627\u0644\u062c\u0631\u064a\u060c \u062a\u0647\u064a\u0626 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0644\u0644\u0627\u0646\u0642\u0628\u0627\u0636 \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0628\u062f\u0648\u0631\u0647 \u0625\u0644\u0649 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0641\u064a \u0627\u0644\u062f\u0645.<\/p>\n

\"\"<\/p>\n

\u0639\u0646\u062f\u0645\u0627 \u0643\u0627\u0646 \u0641\u0648\u0643\u0627\u064a \u0628\u0627\u062d\u062b\u064b\u0627 \u0641\u064a \u0645\u0631\u062d\u0644\u0629 \u0645\u0627 \u0628\u0639\u062f \u0627\u0644\u062f\u0643\u062a\u0648\u0631\u0627\u0629 \u0641\u064a \u0642\u0633\u0645 \u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0642\u0644\u0628 \u0628\u062c\u0627\u0645\u0639\u0629 \u0625\u064a\u0645\u0648\u0631\u064a\u060c \u0643\u0627\u0646 \u0639\u0636\u0648\u064b\u0627 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u062a\u064a \u0643\u0627\u0646\u062a \u0623\u0648\u0644 \u0645\u062c\u0645\u0648\u0639\u0629 \u0628\u062d\u062b\u064a\u0629 \u0623\u062b\u0628\u062a\u062a \u0623\u0646 \u0627\u0644\u062a\u0645\u0631\u064a\u0646 \u0627\u0644\u0628\u062f\u0646\u064a \u064a\u0632\u064a\u062f \u0645\u0646 \u0646\u0634\u0627\u0637 \u0627\u0646\u0632\u064a\u0645 (SOD3). \u00a0\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0646\u0632\u064a\u0645 (SOD3) \u062a\u0646\u062e\u0641\u0636 \u0645\u0639 \u0627\u0644\u062a\u0642\u062f\u0645 \u0641\u064a \u0627\u0644\u0639\u0645\u0631 \u0648\u0645\u0639 \u0628\u0639\u0636 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u0631\u0636\u064a\u0629 \u0645\u062b\u0644 \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a \u0648\u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645.<\/p>\n

\u062a\u064f\u062f\u0631\u0633 \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0643\u0639\u0644\u0627\u0645\u0627\u062a \u062d\u064a\u0648\u064a\u0629 (\u0628\u064a\u0644\u0648\u062c\u064a\u0629) \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0648\u0627\u0633\u0639\u0629 \u0645\u0646 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0643\u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0648\u0627\u0644\u0633\u0643\u0631\u064a \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647\u0627 \u0643\u0623\u062f\u0648\u0627\u062a \/ \u0622\u0644\u064a\u0627\u062a \u062a\u0648\u0635\u064a\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \/ \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u062f\u0642\u064a\u0642 \u0625\u0644\u0649 \u0627\u0644\u0645\u0643\u0627\u0646 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641. \u00a0\u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644\u060c \u0627\u0644\u0623\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0646\u062a\u062c\u0647\u0627 \u062e\u0644\u064a\u0629 \u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u062a\u062a\u062d\u0631\u0643 \u0639\u0627\u0626\u062f\u0629 \u0627\u0644\u0649 \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0646\u0641\u0633\u0647\u0627.<\/p>\n

\u062d\u0648\u0627\u0644\u064a \u0648\u0627\u062d\u062f \u0645\u0646 \u0643\u0644 \u0639\u0634\u0631\u0629 \u0623\u0645\u0631\u064a\u0643\u064a\u064a\u0646 \u0645\u0635\u0627\u0628\u0648\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0648\u0641\u0642\u064b\u0627 \u0644\u0645\u0631\u0627\u0643\u0632 \u0627\u0644\u0633\u064a\u0637\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0648\u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646\u0647\u0627.<\/p>\n

\u0645\u0635\u0627\u062f\u0631 \u0645\u0646 \u062f\u0627\u062e\u0644 \u0648\u062e\u0627\u0631\u062c \u0627\u0644\u0646\u0635:<\/strong>
\n1- “\u062a\u0648\u0644\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0623\u0648 \u062a\u0643\u0648\u0651\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u062c\u062f\u064a\u062f\u0629 (angiogenesis) \u0647\u064a \u0639\u0645\u0644\u064a\u0629 \u0641\u064a\u0632\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u062a\u062a\u0634\u0643\u0644 \u0645\u0646 \u062e\u0644\u0627\u0644\u0647\u0627 \u0623\u0648\u0639\u064a\u0629 \u062f\u0645\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u062a\u062a\u0641\u0631\u0639 \u0639\u0646 \u0623\u0648\u0639\u064a\u0629 \u0645\u0648\u062c\u0648\u062f\u0629 \u0645\u0633\u0628\u0642\u064b\u0627.\u00a0 \u062a\u062d\u062f\u062b \u0639\u0645\u0644\u064a\u0629 \u062a\u0643\u0648\u0651\u0646 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0623\u062b\u0646\u0627\u0621 \u062a\u0643\u0648\u0651\u0646 \u0627\u0644\u062c\u0646\u064a\u0646\u060c \u0648\u0628\u0639\u062f\u0647\u0627 \u062a\u0628\u062f\u0623 \u0639\u0645\u0644\u064a\u0629 \u062a\u0648\u0644\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0648\u0630\u0644\u0643 \u0628\u0646\u0645\u0648 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629.\u00a0 \u0639\u0645\u0644\u064a\u0629 \u062a\u0648\u0644\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0647\u064a \u0639\u0645\u0644\u064a\u0629 \u0628\u064a\u0644\u0648\u062c\u064a\u0629 \u0648\u0643\u0630\u0644\u0643 \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u062a\u0626\u0627\u0645 \u0627\u0644\u062c\u0631\u0648\u062d \u0648\u062e\u0644\u0627\u0644 \u0639\u0645\u0644\u064a\u0629 \u062a\u0634\u0643\u0644 \u0627\u0644\u0646\u0633\u064a\u062c \u0627\u0644\u062d\u0628\u064a\u0628\u064a” \u060c \u0645\u0642\u062a\u0628\u0633 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646:\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 https:\/\/ar.wikipedia.org\/wiki\/\u062a\u0648\u0644\u062f_\u0627\u0644\u0623\u0648\u0639\u064a\u0629<\/a>
\n2- “\u0627\u0644\u0627\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0623\u0648 \u0627\u0644\u062d\u0648\u064a\u0635\u0644\u0627\u062a \u062e\u0627\u0631\u062c \u062e\u0644\u0648\u064a\u0629 (exosome) \u0647\u064a \u062d\u0648\u064a\u0635\u0644\u0627\u062a \u0645\u0634\u062a\u0642\u0629 \u0645\u0646 \u0627\u0644\u062e\u0644\u064a\u0629 \u0648\u062a\u0648\u062c\u062f \u0641\u064a \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0633\u0648\u0627\u0626\u0644 \u0627\u0644\u062d\u064a\u0648\u064a\u0629.\u00a0 \u0648\u0647\u0646\u0627\u0643 \u062a\u0642\u0627\u0631\u064a\u0631 \u062d\u0648\u0644 \u0642\u0637\u0631 \u0627\u0644\u0627\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0627\u0646\u0647\u0627 \u062a\u062a\u0631\u0648\u0627\u062d \u0645\u0627 \u0628\u064a\u0646 30 \u0648 100 \u0646\u0627\u0646\u0648\u0645\u062a\u0631 \u0648\u0647\u064a \u0623\u0643\u0628\u0631 \u0645\u0646 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062f\u0647\u0646\u064a\u060c \u0648\u0644\u0643\u0646 \u0623\u0635\u063a\u0631 \u0628\u0643\u062b\u064a\u0631 \u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644 \u0645\u0646 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621. \u0648\u062a\u0641\u0631\u0632 \u0627\u0644\u0627\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0645\u0646 \u0627\u0644\u062e\u0644\u064a\u0629 \u0639\u0646\u062f\u0645\u0627 \u062a\u0646\u062f\u0645\u062c \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0645\u062a\u0639\u062f\u062f\u0629 \u0627\u0644\u062d\u0648\u064a\u0635\u0644\u0627\u062a \u0645\u0639 \u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u062e\u0644\u0648\u064a \u0623\u0648 \u062a\u0641\u0631\u0632 \u0645\u0628\u0627\u0634\u0631\u0629 \u0645\u0646 \u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u064a \u0648\u062a\u0624\u0643\u062f \u0627\u0644\u0627\u062f\u0644\u0629 \u0627\u0644\u0645\u062a\u0631\u0627\u0643\u0645\u0629 \u0639\u0644\u0649 \u0627\u0646 \u0627\u0644\u0627\u0643\u0633\u0648\u0632\u0648\u0645\u0627\u062a \u0644\u0647\u0627 \u0648\u0638\u0627\u0626\u0641 \u0645\u062a\u062e\u0635\u0635\u0629 \u0648\u062a\u0644\u0639\u0628 \u062f\u0648\u0631\u064b\u0627 \u0631\u0626\u064a\u0633\u064a\u064b\u0627 \u0641\u064a\u060c \u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644\u060c \u062a\u062c\u0644\u0637 \u0627\u0644\u062f\u0645” \u060c \u0645\u0642\u062a\u0628\u0633 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646: https:\/\/ar.wikipedia.org\/wiki\/\u0628\u0631\u0648\u062a\u064a\u0646_\u0634\u062d\u0645\u064a<\/a>
\n3- https:\/\/faseb.onlinelibrary.wiley.com\/doi\/10.1096\/fj.202101323R<\/a>
\n4- https:\/\/en.wikipedia.org\/wiki\/ATP7A<\/a>
\n5- “\u0633\u0648\u0628\u0631 \u0623\u0643\u0633\u064a\u062f \u062f\u064a\u0633\u0645\u064a\u0648\u062a\u0627\u0632 \u0648\u064a\u0633\u0645\u0649 \u0623\u064a\u0636\u064b\u0627 \u0628\u062f\u064a\u0633\u0645\u0648\u062a\u0627\u0632 \u0627\u0644\u0641\u0627\u0626\u0642 (Superoxide dismutase) \u0634\u064a\u0641\u0631\u062a\u0647 \u0627\u0644\u0645\u062e\u062a\u0635\u0631\u0629 \u0647\u0648 \u0625\u0646\u0632\u064a\u0645 \u064a\u062d\u0641\u0632 \u062f\u064a\u0633\u0645\u0648\u062a\u0627\u0632 \u0627\u0644\u0641\u0627\u0626\u0642 \u0625\u0644\u0649 \u0623\u0643\u0633\u062c\u064a\u0646\u00a0 \u0648\u0628\u064a\u0631\u0648\u0627\u0643\u0633\u064a\u062f \u0627\u0644\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646 (H2O2)\u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a\u060c \u0641\u0647\u0648 \u064a\u0639\u062a\u0628\u0631 \u0625\u0646\u0632\u064a\u0645\u064b\u0627 \u0647\u0627\u0645\u064b\u0627 \u0641\u064a \u0645\u0636\u0627\u062f\u0627\u062a \u0627\u0644\u0644\u0623\u0643\u0633\u062f\u0629 \u0641\u064a \u062c\u0645\u064a\u0639 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u062a\u0642\u0631\u064a\u0628\u0627. \u0623\u0647\u0645 \u0648\u0638\u064a\u0641\u0629 \u0644\u0647\u0630\u0627 \u0627\u0644\u0625\u0646\u0632\u064a\u0645 \u0647\u0648 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u062d\u064a\u0648\u064a\u0629 \u0627\u0644\u062e\u0644\u0627\u064a\u0627\u060c \u0648\u062a\u0642\u0644\u064a\u0644 \u0633\u0631\u0639\u0629 \u062a\u062f\u0645\u064a\u0631\u0647\u0627”. \u0645\u0642\u062a\u0628\u0633 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646: https:\/\/ar.wikipedia.org\/wiki\/\u0633\u0648\u0628\u0631_\u0623\u0643\u0633\u064a\u062f_\u062f\u064a\u0633\u0645\u064a\u0648\u062a\u0627\u0632<\/a>
\n6- https:\/\/en.wikipedia.org\/wiki\/SOD3<\/a>
\n7- “\u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u0621 (Smooth muscle) \u0647\u064a \u062a\u0644\u0643 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u062a\u064a \u0644\u0627 \u064a\u062a\u062d\u0643\u0645 \u0628\u0647\u0627 \u0627\u0644\u0627\u0646\u0633\u0627\u0646 \u0648\u0644\u0627 \u062a\u062e\u0636\u0639 \u0644\u0647 \u0641\u064a \u062d\u0631\u0643\u062a\u0647\u0627 \u0648\u064a\u064f\u0637\u0644\u0642 \u0639\u0644\u064a\u0647\u0627 \u0627\u0633\u0645 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u0621 \u0644\u0623\u0646\u0647\u0627 \u0644\u0627 \u062a\u0628\u062f\u064a \u0623\u064a\u0629 \u062e\u0637\u0648\u0637 \u0644\u064a\u0641\u064a\u0629 \u062a\u062d\u062a \u0627\u0644\u0645\u062d\u0647\u0631.\u00a0 \u062a\u0648\u062c\u062f \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0645\u0644\u0633\u0627\u0621 \u0641\u064a \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062a\u062c\u0648\u064a\u0641\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u062a\u0642\u0644\u0635 \u0622\u0644\u064a\u0627\u064b \u0645\u062b\u0644 \u0627\u0644\u0645\u0639\u062f\u0629 \u0648\u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0648\u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0648\u0627\u0644\u0631\u062d\u0645 \u0648\u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0628\u0648\u0644\u064a” \u060c \u0645\u0642\u062a\u0628\u0633 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646: https:\/\/ar.wikipedia.org\/wiki\/\u0639\u0636\u0644\u0627\u062a_\u0645\u0644\u0633\u0627\u0621<\/a>
\n8- “\u0627\u0644\u0639\u0636\u0644\u0629 \u0627\u0644\u0647\u064a\u0643\u0644\u064a\u0629 \u0643\u0645\u0627 \u062a\u064f\u0639\u0631\u0641 \u0628\u0627\u0633\u0645 \u0627\u0644\u0639\u0636\u0644\u0629 \u0627\u0644\u0645\u062e\u0637\u0637\u0629 (Skeletal muscle \u0623\u0648 striated muscle \u0623\u0648 striped muscle) \u0647\u064a \u0627\u0644\u0645\u062d\u0631\u0643 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0644\u062c\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u0648\u062a\u0634\u0645\u0644 \u0623\u063a\u0644\u0628 \u0639\u0636\u0644\u0627\u062a \u062c\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646\u061b \u0641\u0647\u064a \u062a\u0634\u0645\u0644 \u0645\u0627 \u0646\u0633\u0628\u062a\u0647 40% \u0645\u0646 \u0648\u0632\u0646 \u0627\u0644\u062c\u0633\u0645\u060c \u0648\u064a\u0648\u062c\u062f \u0641\u064a \u0627\u0644\u062c\u0633\u0645 \u0646\u062d\u0648 475 \u0639\u0636\u0644\u0629 \u0647\u064a\u0643\u0644\u064a\u0629 \u0645\u062e\u062a\u0644\u0641\u0629\u060c \u0648\u0648\u0638\u064a\u0641\u062a\u0647\u0627 \u0647\u064a \u062a\u062d\u0631\u064a\u0643 \u0639\u0638\u0627\u0645 \u0627\u0644\u0647\u064a\u0643\u0644 \u0627\u0644\u0639\u0638\u0645\u064a \u0648\u0627\u0644\u062a\u062d\u0643\u0645 \u0641\u064a \u0645\u0648\u0636\u0639 \u0643\u0644\u064d \u0645\u0646\u0647\u0627” \u060c \u0645\u0642\u062a\u0628\u0633 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646: https:\/\/ar.wikipedia.org\/wiki\/\u0639\u0636\u0644\u0629_\u0647\u064a\u0643\u0644\u064a\u0629<\/a>
\n9- https:\/\/ar.wikipedia.org\/wiki\/\u0645\u0631\u0643\u0628\u0627\u062a_\u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646_\u0627\u0644\u062a\u0641\u0627\u0639\u0644\u064a\u0629<\/a>
\n\u0627\u0644\u0645\u0635\u062f\u0631 \u0627\u0644\u0631\u0626\u064a\u0633:<\/strong>
\nhttps:\/\/jagwire.augusta.edu\/new-evidence-of-how-exercise-can-counter-diabetes-damage<\/a><\/h5>\n
\"\"
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