{"id":15127,"date":"2022-03-04T01:18:14","date_gmt":"2022-03-03T22:18:14","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=15127"},"modified":"2022-03-04T01:18:14","modified_gmt":"2022-03-03T22:18:14","slug":"%d9%82%d8%b6%d8%a7%d9%8a%d8%a7-%d8%af%d9%88%d8%a7%d8%a6%d9%8a%d8%a9-%d8%a7%d9%84%d8%a3%d9%85%d8%b1%d8%a7%d8%b6-%d8%a7%d9%84%d9%86%d8%a7%d8%af%d8%b1%d8%a9-%d9%88%d8%a7%d9%84%d8%a3%d8%af%d9%88%d9%8a","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=15127","title":{"rendered":"\u0642\u0636\u0627\u064a\u0627 \u062f\u0648\u0627\u0626\u064a\u0629 .. \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0646\u0627\u062f\u0631\u0629 \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629\u060c \u0645\u0634\u0643\u0644\u0629 \u0635\u062d\u064a\u0629 \u0644\u0647\u0627 \u0623\u0628\u0639\u0627\u062f \u0627\u0642\u062a\u0635\u0627\u062f\u064a\u0629 \u0648\u0623\u062e\u0644\u0627\u0642\u064a\u0629 \u064a\u0646\u0628\u063a\u064a \u0645\u0639\u0627\u0644\u062c\u062a\u0647\u0627 – \u0628\u0642\u0644\u0645 \u0627\u0644\u0635\u064a\u062f\u0644\u064a \u063a\u0633\u0627\u0646 \u0639\u0644\u064a \u0628\u0648\u062e\u0645\u0633\u064a\u0646*"},"content":{"rendered":"

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\"\"<\/p>\n

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\u0641\u064a \u0639\u0627\u0645 2016 \u060c \u0648\u0627\u0641\u0642\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0639\u0644\u0649 \u062a\u0633\u0648\u064a\u0642 (Nusinersen) \u0639\u0644\u0649 \u0623\u0646\u0647 \u0623\u0648\u0644 \u062f\u0648\u0627\u0621 \u0645\u0639\u062a\u0645\u062f \u0644\u0639\u0644\u0627\u062c \u0636\u0645\u0648\u0631 \u0627\u0644\u0639\u0636\u0644\u0627\u062a \u0627\u0644\u0634\u0648\u0643\u064a \u0641\u064a \u0637\u0628 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0648\u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646. \u062a\u0628\u0644\u063a \u062a\u0643\u0644\u0641\u0629 (\u00ae Nusinersen – Spinraza) 750\u060c000 \u062f\u0648\u0644\u0627\u0631 \u0623\u0645\u0631\u064a\u0643\u064a (2\u060c812\u060c500 \u0631\u064a\u0627\u0644 \u0633\u0639\u0648\u062f\u064a) \u0641\u064a \u0627\u0644\u0633\u0646\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0648 375\u060c000 \u062f\u0648\u0644\u0627\u0631 \u0623\u0645\u0631\u064a\u0643\u064a (1\u060c406\u060c205 \u0631\u064a\u0627\u0644 \u0633\u0639\u0648\u062f\u064a) \u0633\u0646\u0648\u064a\u064b\u0627 \u0644\u0644\u062c\u0631\u0639\u0627\u062a \u0627\u0644\u062a\u0627\u0644\u064a\u0629 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0627\u0639\u062a\u0628\u0627\u0631\u064b\u0627 \u0645\u0646 2019.<\/p>\n

\"\"<\/p>\n

\u062e\u0644\u0635\u062a \u062f\u0631\u0627\u0633\u0629 \u0623\u062e\u0631\u0649 \u0628\u0623\u062b\u0631 \u0631\u062c\u0639\u064a \u0625\u0644\u0649 \u0623\u0646 \u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u0627\u0644\u0639\u0631\u0628\u064a\u0629 \u0627\u0644\u0633\u0639\u0648\u062f\u064a\u0629 \u0644\u062f\u064a\u0647\u0627 \u0648\u0627\u062d\u062f\u0629 \u0645\u0646 \u0623\u0639\u0644\u0649 \u0645\u0639\u062f\u0644\u0627\u062a \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u0623\u064a\u0636\u064a\u0629 \u0627\u0644\u0645\u0648\u0631\u0648\u062b\u0629 \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645. \u0623\u062c\u0631\u0649 \u0641\u0631\u064a\u0642 \u0645\u0646 \u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0645\u0646 \u0642\u0633\u0645 \u0637\u0628 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0641\u064a \u0645\u0631\u0643\u0632 \u0627\u0644\u0645\u0644\u0643 \u0639\u0628\u062f \u0627\u0644\u0639\u0632\u064a\u0632 \u0627\u0644\u0637\u0628\u064a \u0645\u0631\u0627\u062c\u0639\u0629 \u0628\u0623\u062b\u0631 \u0631\u062c\u0639\u064a \u0644\u0645\u062f\u0629 \u062b\u0644\u0627\u062b\u0629 \u0639\u0634\u0631 \u0639\u0627\u0645\u064b\u0627 \u0644\u0644\u0633\u062c\u0644\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0644\u062d\u062f\u064a\u062b\u064a \u0627\u0644\u0648\u0644\u0627\u062f\u0629 \u0628\u064a\u0646 \u0639\u0627\u0645\u064a 2001 \u0648 2014.<\/p>\n

\u062a\u0645 \u0627\u0644\u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0645\u062b\u064a\u0644 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0644\u0644\u0623\u062e\u0637\u0627\u0621 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 (IEM) \u0645\u0646 \u062e\u0644\u0627\u0644 \u0631\u0645\u0648\u0632 \u0627\u0644\u0645\u0631\u0636 \u0648\u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u0634\u062e\u064a\u0635\u064a\u0629 \u0627\u0644\u062a\u064a \u0623\u062c\u0631\u064a\u062a \u0644\u0646\u0634\u0627\u0637 \u0645\u0631\u0636 \u0648\u0631\u0627\u062b\u064a \/ \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a \u0645\u0634\u0628\u0648\u0647. (IEM) \u0647\u064a \u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0648\u0631\u0627\u062b\u064a\u0629 \u0648\u0631\u0627\u062b\u064a\u0629 \u0646\u0627\u062f\u0631\u0629 \u0644\u0627 \u064a\u0633\u062a\u0637\u064a\u0639 \u0641\u064a\u0647\u0627 \u0627\u0644\u062c\u0633\u0645 \u062a\u062d\u0648\u064a\u0644 \u0627\u0644\u0637\u0639\u0627\u0645 \u0625\u0644\u0649 \u0637\u0627\u0642\u0629 \u0628\u0634\u0643\u0644 \u0635\u062d\u064a\u062d.<\/p>\n

\u062a\u062d\u062f\u062b \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0639\u0627\u062f\u0629\u064b \u0628\u0633\u0628\u0628 \u0639\u064a\u0648\u0628 \u0641\u064a \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0645\u0639\u064a\u0646\u0629 (\u0625\u0646\u0632\u064a\u0645\u0627\u062a) \u062a\u0633\u0627\u0639\u062f \u0641\u064a \u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0623\u062c\u0632\u0627\u0621 \u0645\u0646 \u0627\u0644\u0637\u0639\u0627\u0645. \u0635\u0646\u0641 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0648\u0641\u0642\u064b\u0627 \u0644\u0646\u0648\u0639 \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628 \u0627\u0644\u0630\u064a \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646\u0647 \u060c \u0645\u0646 \u0628\u064a\u0646 110601 \u0637\u0641\u0644 \u0648\u0644\u062f\u0648\u0627 \u0641\u064a \u062a\u0644\u0643 \u0627\u0644\u0641\u062a\u0631\u0629 \u060c \u062a\u0645 \u062a\u0634\u062e\u064a\u0635 187 \u0645\u0631\u064a\u0636\u064b\u0627 \u0628\u0623\u0646\u0648\u0627\u0639 \u0645\u062e\u062a\u0644\u0641\u0629 \u0645\u0646 (IEM) \u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0639\u062f\u0645 \u062a\u062d\u0645\u0644 \u0627\u0644\u0641\u0631\u0643\u062a\u0648\u0632 \u060c \u0627\u0644\u062c\u0627\u0644\u0627\u0643\u062a\u0648\u0632 \u0641\u064a \u0627\u0644\u062f\u0645 \u060c \u0645\u0631\u0636 \u0628\u0648\u0644 \u0634\u0631\u0627\u0628 \u0627\u0644\u0642\u064a\u0642\u0628 (MSUD) \u0648\u0628\u064a\u0644\u0629 \u200b\u200b\u0627\u0644\u0641\u064a\u0646\u064a\u0644 \u0643\u064a\u062a\u0648\u0646 (PKU) \u0648\u0645\u0627 \u0625\u0644\u0649 \u0630\u0644\u0643.<\/p>\n

\u061b\u061b\u0623\u062d\u062f \u0627\u0644\u0642\u064a\u0648\u062f \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0644\u062a\u062d\u0633\u064a\u0646 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0646\u0627\u062f\u0631\u0629 \u0647\u0648 \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0648\u062a\u0648\u0627\u0641\u0631\u0647\u0627\u061b\u061b<\/strong><\/span><\/p>\n

\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0639\u0644\u0649 \u0648\u062c\u0647 \u0627\u0644\u062a\u062d\u062f\u064a\u062f \u060c \u064a\u0645\u062b\u0644 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u062c\u063a\u0631\u0627\u0641\u064a \u062a\u062d\u062f\u064a\u064b\u0627 \u0644\u0644\u0645\u0631\u0636\u0649 \u0648\u0645\u0642\u062f\u0645\u064a \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u064a\u0634\u0648\u0646 \u0641\u064a \u0627\u0644\u0645\u0646\u0627\u0637\u0642 \u0627\u0644\u0631\u064a\u0641\u064a\u0629 \u062d\u064a\u062b \u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u062a\u0645 \u062a\u0648\u0641\u064a\u0631 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0645\u062a\u062e\u0635\u0635\u0629 \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u0645\u0633\u062a\u0634\u0641\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062e\u0635\u0635\u0629 \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u0645\u062f\u0646 \u0627\u0644\u0643\u0628\u064a\u0631\u0629.<\/p>\n

\u064a\u062c\u0628 \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u064a\u0634\u0648\u0646 \u0641\u064a \u0627\u0644\u0645\u062f\u0646 \u0627\u0644\u0635\u063a\u064a\u0631\u0629 \u0648\u0644\u064a\u0633 \u0644\u062f\u064a\u0647\u0645 \u062a\u0623\u0645\u064a\u0646 \u0637\u0628\u064a \u0627\u0644\u0633\u0641\u0631 \u0644\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0637\u0628\u064a\u0629. \u064a\u062a\u0645 \u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u062f\u0639\u0645 \u0627\u0644\u0645\u0627\u0644\u064a \u0623\u064a\u0636\u064b\u0627 \u0644\u0645\u0642\u062f\u0645 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \/ \u0627\u0644\u0648\u0627\u0644\u062f\u064a\u0646 \u0644\u0644\u0645\u0631\u064a\u0636 \u0644\u062a\u063a\u0637\u064a\u0629 \u0646\u0641\u0642\u0627\u062a \u0627\u0644\u0633\u0641\u0631 \u0648\u0627\u0644\u0625\u0642\u0627\u0645\u0629 \u0645\u0645\u0627 \u064a\u0641\u0631\u0636 \u0639\u0628\u0626\u064b\u0627 \u0627\u0642\u062a\u0635\u0627\u062f\u064a\u064b\u0627 \u0643\u0628\u064a\u0631\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u062d\u0643\u0648\u0645\u0629.<\/p>\n

\u0628\u062f\u0648\u0646 \u062a\u0623\u0645\u064a\u0646 \u0635\u062d\u064a \u0648\u0646\u0638\u0627\u0645 \u0627\u0644\u0633\u062f\u0627\u062f \u0627\u0644\u062d\u0627\u0644\u064a \u0641\u064a \u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u060c \u0647\u0646\u0627\u0643 \u0642\u064a\u0648\u062f \u0634\u062f\u064a\u062f\u0629 \u0639\u0644\u0649 \u062f\u0641\u0639 \u062b\u0645\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0644\u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u062a\u064a \u0633\u062a\u0624\u062e\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0648\u062a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u0645\u0631\u0636. \u064a\u0645\u062b\u0644 \u062a\u0648\u0641\u0631 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0648\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0623\u064a\u0636\u064b\u0627 \u062a\u062d\u062f\u064a\u064b\u0627 \u0644\u0645\u0642\u062f\u0645\u064a \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0641\u064a \u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u0627\u0644\u0639\u0631\u0628\u064a\u0629 \u0627\u0644\u0633\u0639\u0648\u062f\u064a\u0629.<\/p>\n

\u0642\u062f \u062a\u0624\u062f\u064a \u0627\u0644\u0628\u064a\u0631\u0648\u0642\u0631\u0627\u0637\u064a\u0629 \u0627\u0644\u0645\u0635\u062d\u0648\u0628\u0629 \u0628\u0627\u0644\u0633\u0644\u0639 \u0627\u0644\u0645\u0633\u062a\u0648\u0631\u062f\u0629 \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0625\u0644\u0649 \u062a\u0623\u062e\u064a\u0631 \u062e\u0637\u0629 \u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0631\u064a\u0636. \u0623\u0648\u0635\u062a \u0648\u0632\u0627\u0631\u0629 \u0627\u0644\u0635\u062d\u0629 \u0628\u0628\u0639\u0636 \u0627\u0644\u0627\u0642\u062a\u0631\u0627\u062d\u0627\u062a \u0644\u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0641\u064a \u0627\u0644\u0643\u0634\u0641 \u0627\u0644\u0645\u0628\u0643\u0631 \u0639\u0646 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0646\u0627\u062f\u0631\u0629 \u0648\u062f\u0639\u0645 \u0627\u0644\u0645\u0631\u0636\u0649 \u0644\u062a\u0644\u0642\u064a \u062e\u062f\u0645\u0627\u062a \u0635\u062d\u064a\u0629 \u0623\u0641\u0636\u0644.<\/p>\n

\u0623\u062d\u062f\u0647\u0627 \u0647\u0648 \u0633\u0646 \u062a\u0634\u0631\u064a\u0639\u0627\u062a \u0644\u062f\u0639\u0645 \u0627\u0644\u0645\u0631\u0636\u0649 \u0648\u0623\u0633\u0631\u0647\u0645 \u0648\u062a\u0642\u062f\u064a\u0645 \u062d\u0648\u0627\u0641\u0632 \u0644\u0634\u0631\u0643\u0627\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0644\u062a\u0637\u0648\u064a\u0631 \u0623\u062f\u0648\u064a\u0629 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0646\u0627\u062f\u0631\u0629. \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0630\u0644\u0643 \u060c \u062a\u0645 \u0646\u0634\u0631 \u0645\u0631\u0627\u062c\u0639\u0629 \u0634\u0627\u0645\u0644\u0629 \u0644\u062a\u062d\u062f\u064a\u062f \u0648\u062c\u0647\u0629 \u0646\u0638\u0631 \u0634\u0631\u0643\u0627\u062a \u0627\u0644\u062a\u0623\u0645\u064a\u0646 \u062d\u0648\u0644 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u0649 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0625\u062c\u0631\u0627\u0621 \u062a\u062d\u0644\u064a\u0644 \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u062a\u0643\u0644\u0641\u0629 (CEA).<\/p>\n

\"\"<\/p>\n

\u0642\u0628\u0644 \u0639\u0642\u062f \u0645\u0646 \u0627\u0644\u0632\u0645\u0627\u0646 \u060c \u0643\u0627\u0646 \u0644\u062f\u0649 \u0635\u0627\u0646\u0639\u064a \u0627\u0644\u0633\u064a\u0627\u0633\u0627\u062a \u0641\u0643\u0631\u0629 \u0633\u0627\u0626\u062f\u0629 \u0628\u0623\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0644\u0647\u0627 \u062a\u0623\u062b\u064a\u0631 \u0645\u062d\u062f\u0648\u062f \u0639\u0644\u0649 \u0645\u064a\u0632\u0627\u0646\u064a\u0629 \u0627\u0644\u0635\u064a\u062f\u0644\u0629 \u0644\u0623\u0646\u0647\u0627 \u062a\u0633\u062a\u0647\u062f\u0641 \u0634\u0631\u064a\u062d\u0629 \u0633\u0643\u0627\u0646\u064a\u0629 \u0635\u063a\u064a\u0631\u0629. \u062a\u0645 \u0646\u0634\u0631 \u0639\u062f\u0629 \u062a\u0642\u0627\u0631\u064a\u0631 \u0644\u0644\u0625\u0628\u0644\u0627\u063a \u0639\u0646 \u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0641\u064a \u062c\u0645\u064a\u0639 \u0623\u0646\u062d\u0627\u0621 \u0627\u0644\u0639\u0627\u0644\u0645.<\/p>\n

\u0642\u062f\u0631\u062a \u062f\u0631\u0627\u0633\u0629 \u062d\u062f\u064a\u062b\u0629 \u0623\u0646 \u0627\u0644\u062d\u0635\u0629 \u0627\u0644\u0633\u0648\u0642\u064a\u0629 \u0644\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0641\u064a \u0627\u0644\u0627\u062a\u062d\u0627\u062f \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a (EU) \u0633\u062a\u0631\u062a\u0641\u0639 \u0645\u0646 3\u066a \u0625\u0644\u0649 5\u066a \u0628\u064a\u0646 \u0639\u0627\u0645\u064a 2010 \u0648 2020 \u060c \u0628\u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u062a\u0643\u0644\u0641\u0629 \u0633\u0646\u0648\u064a\u0629 \u0644\u0643\u0644 \u0645\u0631\u064a\u0636 \u0644\u0643\u0644 \u0645\u0631\u0636 \u064a\u0628\u0644\u063a 32242 \u064a\u0648\u0631\u0648 \u0645\u0639 \u0646\u0637\u0627\u0642 \u064a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 1\u060c251 \u064a\u0648\u0631\u0648 \u0648 407\u060c631 \u064a\u0648\u0631\u0648.<\/p>\n

\u0643\u0627\u0646 \u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0631\u062a\u0641\u0639 \u0627\u0644\u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a\u0629 \u0645\u0646 5 \u0645\u0644\u0627\u064a\u064a\u0646 \u064a\u0648\u0631\u0648 \u0641\u064a \u0627\u0644\u0639\u0627\u0645 \u0628\u0639\u062f \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0623\u0648\u0644 \u0639\u0642\u0627\u0631 \u064a\u062a\u064a\u0645 \u0625\u0644\u0649 143 \u0645\u0644\u064a\u0648\u0646 \u064a\u0648\u0631\u0648 \u0641\u064a \u0627\u0644\u0633\u0646\u0629 \u0627\u0644\u0639\u0627\u0634\u0631\u0629 \u060c \u0642\u0628\u0644 \u0627\u0644\u0627\u0646\u062e\u0641\u0627\u0636 \u0648\u0627\u0644\u062b\u0628\u0627\u062a \u0639\u0646\u062f \u062d\u0648\u0627\u0644\u064a 110 \u0645\u0644\u064a\u0648\u0646 \u064a\u0648\u0631\u0648 \u0633\u0646\u0648\u064a\u064b\u0627 \u0641\u064a \u0627\u0644\u0628\u0644\u062f\u0627\u0646 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0648\u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u0627\u0644\u0645\u062a\u062d\u062f\u0629 (\u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u0627\u0644\u0645\u062a\u062d\u062f\u0629).<\/p>\n

9.6 % \u0645\u0646 \u0625\u062c\u0645\u0627\u0644\u064a \u0627\u0644\u0625\u0646\u0641\u0627\u0642 \u0639\u0644\u0649 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 (451 \u0645\u0644\u064a\u0648\u0646 \u062f\u0648\u0644\u0627\u0631) \u062a\u0645 \u0625\u0646\u0641\u0627\u0642\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 (\u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629) \u0641\u064a \u0639\u0627\u0645 2017.<\/p>\n

\u00a0\u061b\u061b\u0644\u0644\u0623\u0633\u0641 \u0644\u0627 \u062a\u0648\u062c\u062f \u062f\u0631\u0627\u0633\u0627\u062a \u0623\u0648 \u062a\u0642\u0627\u0631\u064a\u0631 \u062a\u0642\u062f\u0631 \u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0641\u064a \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0634\u0631\u0642 \u0627\u0644\u0623\u0648\u0633\u0637 \u0623\u0648 \u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u0627\u0644\u0639\u0631\u0628\u064a\u0629 \u0627\u0644\u0633\u0639\u0648\u062f\u064a\u0629\u061b\u061b<\/strong><\/span><\/p>\n

\u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u0633\u064a\u0643\u0648\u0646 \u062a\u062d\u062f\u064a\u064b\u0627 \u0644\u0648\u0627\u0636\u0639\u064a \u0627\u0644\u0633\u064a\u0627\u0633\u0627\u062a \u0648\u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0644\u062a\u0646\u0641\u064a\u0630 \u0633\u064a\u0627\u0633\u0627\u062a \u062a\u062a\u0639\u0644\u0642 \u0628\u062a\u0645\u0648\u064a\u0644 \u0648\u0633\u062f\u0627\u062f \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0648\u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629.<\/p>\n

\u064a\u062a\u0645\u062b\u0644 \u0627\u0644\u062a\u062d\u062f\u064a \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0641\u064a \u062a\u0637\u0648\u064a\u0631 \u0633\u064a\u0627\u0633\u0627\u062a \u0627\u0644\u0625\u0646\u0641\u0627\u0642 \u0641\u064a \u062a\u062d\u062f\u064a\u062f \u062a\u0639\u0631\u064a\u0641 \u0648\u0627\u0636\u062d \u0644\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0646\u0627\u062f\u0631\u0629. \u062a\u0645 \u062a\u0639\u064a\u064a\u0646 \u0627\u0644\u062a\u0639\u0631\u064a\u0641\u0627\u062a \u0627\u0644\u0645\u0642\u062f\u0645\u0629 \u0639\u0644\u0649 \u0623\u0646\u0647\u0627 \u0627\u0646\u062a\u0634\u0627\u0631 \u0644\u0643\u0644 100\u060c000 \u0645\u0646 \u0627\u0644\u0633\u0643\u0627\u0646 \u0644\u062a\u0645\u0643\u064a\u0646 \u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0639\u0628\u0631 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0623\u062e\u0631\u0649 \u0627\u0644\u062a\u064a \u0644\u064a\u0633\u062a \u062f\u0642\u064a\u0642\u0629 \u0628\u0627\u0644\u0636\u0631\u0648\u0631\u0629 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0629.<\/p>\n

\u0639\u0644\u0627\u0648\u0629 \u0639\u0644\u0649 \u0630\u0644\u0643 \u060c \u0647\u0646\u0627\u0643 \u062a\u0628\u0627\u064a\u0646 \u0643\u0628\u064a\u0631 \u0641\u064a \u0639\u062f\u062f \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0644\u0643\u0644 100\u060c000 \u0641\u0631\u062f \u062d\u0648\u0644 \u0627\u0644\u0639\u0627\u0644\u0645. \u062a\u0645 \u062a\u062d\u062f\u064a\u062f \u0646\u0637\u0627\u0642 \u0645\u0646 5 \u0625\u0644\u0649 76 \u062d\u0627\u0644\u0629 \u0644\u0643\u0644 100\u060c000 \u0645\u0646 \u0627\u0644\u0633\u0643\u0627\u0646 \u0643\u062a\u0639\u0631\u064a\u0641 \u0644\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0646\u0627\u062f\u0631\u0629 \u0645\u0646 \u0645\u0646\u0638\u0645\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629. \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u060c \u062a\u0633\u062a\u062e\u062f\u0645 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 (FDA) \u062a\u0639\u0631\u064a\u0641\u064b\u0627 \u0648\u0636\u0639\u0647 \u0642\u0627\u0646\u0648\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0641\u064a \u0639\u0627\u0645 1983 \u0648\u0627\u0633\u062a\u0646\u0627\u062f\u064b\u0627 \u0625\u0644\u0649 \u0627\u0646\u062a\u0634\u0627\u0631 \u0623\u0642\u0644 \u0645\u0646 200\u060c000 \u0645\u0631\u064a\u0636 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0648\u0642\u062a.<\/p>\n

\u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u062a\u0642\u062f\u064a\u0631 \u0627\u0644\u062d\u0627\u0644\u064a \u0644\u0639\u062f\u062f \u0633\u0643\u0627\u0646 \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u060c \u0641\u0647\u0648 \u064a\u0642\u0627\u0631\u0628 61 \u062d\u0627\u0644\u0629 \u0644\u0643\u0644 100\u060c000. \u0641\u064a \u0627\u0644\u064a\u0627\u0628\u0627\u0646 \u060c \u064a\u0639\u062a\u0628\u0631 \u0627\u0644\u0645\u0631\u0636 \u0646\u0627\u062f\u0631\u064b\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0645\u0639\u062f\u0644 \u0627\u0644\u0627\u0646\u062a\u0634\u0627\u0631 \u0623\u0642\u0644 \u0645\u0646 50\u060c000 \u0645\u0631\u064a\u0636 \u0623\u0648 \u0623\u0642\u0644 \u0645\u0646 40 \u0644\u0643\u0644 100\u060c000 \u0645\u0639 \u0627\u0644\u0623\u062e\u0630 \u0641\u064a \u0627\u0644\u0627\u0639\u062a\u0628\u0627\u0631 \u0627\u0644\u062a\u0642\u062f\u064a\u0631 \u0627\u0644\u062d\u0627\u0644\u064a \u0644\u0644\u0633\u0643\u0627\u0646.<\/p>\n

\u0627\u0644\u062a\u062d\u062f\u064a \u0627\u0644\u0622\u062e\u0631 \u0647\u0648 \u0627\u0644\u0633\u064a\u0627\u0642 \u0627\u0644\u0623\u062e\u0644\u0627\u0642\u064a \u0644\u062a\u0645\u0648\u064a\u0644 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0628\u0627\u0647\u0638\u0629 \u0627\u0644\u062b\u0645\u0646 \u0644\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0646\u0627\u062f\u0631\u0629. \u0644\u0627 \u064a\u0632\u0627\u0644 \u0627\u0644\u0635\u0631\u0627\u0639 \u0645\u0646 \u0623\u062c\u0644 \u0625\u064a\u062c\u0627\u062f \u062a\u0648\u0627\u0632\u0646 \u0628\u064a\u0646 \u0627\u0644\u0642\u064a\u0645 \u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639\u064a\u0629 \u0648\u0641\u0639\u0627\u0644\u064a\u0629 \u062a\u0643\u0644\u0641\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0643\u0644\u0641\u0629 \u0644\u064a\u0633 \u0641\u0642\u0637 \u0641\u064a \u062a\u0639\u0648\u064a\u0636 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u064a\u062a\u064a\u0645\u0629 \u0648\u0644\u0643\u0646 \u0645\u0639 \u0627\u0644\u062a\u0642\u0646\u064a\u0627\u062a \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0641\u064a \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0645\u062c\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u0631\u0636 \u0623\u0645\u0631\u064b\u0627 \u0645\u062b\u064a\u0631\u064b\u0627 \u0644\u0644\u062c\u062f\u0644.<\/p>\n

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\u0641\u064a \u0642\u064a\u0627\u0633 (QALYs) \u0627\u0644\u0646\u0645\u0648\u0630\u062c\u064a (\u064a\u062a\u0645 \u0627\u062d\u062a\u0633\u0627\u0628 (QALYs) \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u0642\u062f\u064a\u0631 \u0633\u0646\u0648\u0627\u062a \u0627\u0644\u0639\u0645\u0631 \u0627\u0644\u0645\u062a\u0628\u0642\u064a\u0629 \u0644\u0644\u0645\u0631\u064a\u0636 \u0628\u0639\u062f \u0639\u0644\u0627\u062c \u0623\u0648 \u062a\u062f\u062e\u0644 \u0645\u0639\u064a\u0646 \u0648\u0627\u0644\u0648\u0632\u0646 \u0643\u0644 \u0639\u0627\u0645 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0642\u064a\u0627\u0633 \u062c\u0648\u062f\u0629 \u0627\u0644\u062d\u064a\u0627\u0629)\u00a0 \u060c \u064a\u064f\u0637\u0644\u0628 \u0645\u0646 \u0627\u0644\u0645\u0631\u064a\u0636 \u0623\u0648 \u0627\u0644\u0645\u0633\u062a\u062c\u064a\u0628 \u0627\u0644\u0622\u062e\u0631 \u062a\u062e\u064a\u0644 \u0646\u0641\u0633\u0647 \u0641\u064a \u062d\u0627\u0644\u062a\u064a\u0646 \u0635\u062d\u064a\u062a\u064a\u0646 \u0645\u062e\u062a\u0644\u0641\u062a\u064a\u0646 \u060c \u0648\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0642\u064a\u0645\u0629 \u0627\u0644\u0646\u0633\u0628\u064a\u0629 \u0644\u0642\u0636\u0627\u0621 \u0627\u0644\u0648\u0642\u062a \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 A \u0645\u0642\u0627\u0628\u0644 \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 B \u060c \u0628\u062f\u0644\u0627\u064b \u0645\u0646 \u0630\u0644\u0643 \u060c \u062a\u0633\u0645\u062d \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0628\u062a\u0636\u062e\u0645 (QALYs) \u0641\u064a \u0628\u0639\u0636 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0628\u0646\u0627\u0621 \u0639\u0644\u0649 \u0634\u062f\u0629 \u0627\u0644\u0645\u0631\u0636.<\/p>\n

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