{"id":14238,"date":"2022-01-07T22:18:39","date_gmt":"2022-01-07T19:18:39","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=14238"},"modified":"2022-01-07T22:18:39","modified_gmt":"2022-01-07T19:18:39","slug":"%d9%86%d8%b8%d8%a7%d9%85-%d8%aa%d8%ad%d8%b1%d9%8a%d8%b1-%d8%b1%d8%a6%d9%8a%d8%b3%d9%8a-%d8%ac%d8%af%d9%8a%d8%af-%d9%8a%d8%af%d8%b1%d8%ac-%d8%ac%d9%8a%d9%86%d8%a7%d8%aa-%d9%83%d8%a7%d9%85%d9%84%d8%a9","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=14238","title":{"rendered":"\u0646\u0638\u0627\u0645 \u062a\u062d\u0631\u064a\u0631 \u0631\u0626\u064a\u0633\u064a \u062c\u062f\u064a\u062f \u064a\u062f\u0631\u062c \u062c\u064a\u0646\u0627\u062a \u0643\u0627\u0645\u0644\u0629 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 – \u062a\u0631\u062c\u0645\u0629* \u0645\u062d\u0645\u062f \u062c\u0648\u0627\u062f \u0622\u0644 \u0627\u0644\u0633\u064a\u062f \u0646\u0627\u0635\u0631 \u0627\u0644\u062e\u0636\u0631\u0627\u0648\u064a"},"content":{"rendered":"

New prime editing system inserts entire genes in human cells<\/strong>
\n\u00a0(Allessandra Dicorato – \u0627\u0644\u064a\u0633\u0627\u0646\u062f\u0631\u0627 \u062f\u064a\u0643\u0648\u0631\u0627\u062a\u0648)<\/span><\/h3>\n

\u0645\u0644\u062e\u0635 \u0627\u0644\u0645\u0642\u0627\u0644\u0629:<\/strong><\/span><\/p>\n

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( \u0627\u0644\u0645\u0642\u0627\u0644\u0629 )<\/strong><\/p>\n

\"\"
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\u0637\u0648\u0631 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a \u0645\u0639\u0647\u062f “\u0628\u0631\u0648\u062f” \u0648\u062a\u0639\u0646\u064a \u0628\u0627\u0644\u0639\u0631\u0628\u064a\u0629 \u0627\u0644\u0648\u0627\u0633\u0639 (Broad Institute) \u0627\u0644\u062a\u0627\u0628\u0639 \u0644\u0645\u0639\u0647\u062f \u0645\u0627\u0633\u0627\u062a\u0634\u0648\u0633\u062a\u0633 \u0644\u0644\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0627 (MIT) \u0648\u062c\u0627\u0645\u0639\u0629 \u0647\u0627\u0631\u0641\u0627\u0631\u062f \u0646\u0633\u062e\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u064a\u0645\u0643\u0646\u0647\u0627 \u062a\u062b\u0628\u064a\u062a \u0623\u0648 \u062a\u0628\u062f\u064a\u0644 \u062a\u0633\u0644\u0633\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0628\u062d\u062c\u0645 \u0627\u0644\u062c\u064a\u0646\u0627\u062a. \u0648\u0642\u062f \u062a\u0645 \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0623\u0648\u0644 \u0645\u0631\u0629 \u0641\u064a \u0639\u0627\u0645 2019\u060c \u0648\u0647\u0648 \u0637\u0631\u064a\u0642\u0629 \u062f\u0642\u064a\u0642\u0629 \u0644\u0625\u062c\u0631\u0627\u0621 \u0645\u062c\u0645\u0648\u0639\u0629 \u0648\u0627\u0633\u0639\u0629 \u0645\u0646 \u0627\u0644\u062a\u0639\u062f\u064a\u0644\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0627\u0628\u062f\u0627\u0644\u0627\u062a \u0627\u0644\u0635\u063a\u064a\u0631\u0629 \u0648\u0627\u0644\u0625\u062f\u0631\u0627\u062c \u0648\u0627\u0644\u062d\u0630\u0641.<\/p>\n

\u0648\u0641\u064a \u062f\u0631\u0627\u0633\u0629 \u0646\u0634\u0631\u062a \u0641\u064a \u0627\u0644\u0639\u0627\u0634\u0631 \u0645\u0646 \u062f\u064a\u0633\u0645\u0628\u0631 2021 \u0641\u064a \u0645\u062c\u0644\u0629 “\u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0644\u0644\u0637\u0628\u064a\u0639\u0629” (Nature Biotechnology)\u060c \u064a\u0635\u0641 \u0627\u0644\u0641\u0631\u064a\u0642\u064f \u0627\u0644\u062a\u062d\u0631\u064a\u0631\u064e \u0627\u0644\u0623\u0648\u0644\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c (twinPE)\u060c \u0648\u0647\u064a \u062a\u0642\u0646\u064a\u0629 \u062a\u0642\u0648\u0645 \u0628\u0625\u062c\u0631\u0627\u0621 \u062a\u0639\u062f\u064a\u0644\u064a\u0646 \u0631\u0626\u064a\u0633\u064a\u064a\u0646 \u0645\u062a\u062c\u0627\u0648\u0631\u064a\u0646 \u0644\u062a\u0642\u062f\u064a\u0645 \u062a\u0633\u0644\u0633\u0644\u0627\u062a \u0623\u0643\u0628\u0631 \u0645\u0646 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0641\u064a \u0645\u0648\u0627\u0642\u0639 \u0645\u062d\u062f\u062f\u0629 \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0648\u0645 \u0645\u0639 \u0639\u062f\u062f \u0642\u0644\u064a\u0644 \u0645\u0646 \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u062b\u0627\u0646\u0648\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0645\u0631\u063a\u0648\u0628 \u0641\u064a\u0647\u0627. \u0648\u0645\u0639 \u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u0637\u0648\u064a\u0631\u060c \u064a\u0645\u0643\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u062a\u0642\u0646\u064a\u0629 \u0643\u0634\u0643\u0644 \u062c\u062f\u064a\u062f \u0645\u0646 \u0623\u0634\u0643\u0627\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0625\u062f\u062e\u0627\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629 \u0628\u0637\u0631\u064a\u0642\u0629 \u0622\u0645\u0646\u0629 \u0648\u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0644\u0644\u063a\u0627\u064a\u0629 \u0644\u062a\u062d\u0644 \u0645\u062d\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0629 \u0623\u0648 \u0627\u0644\u0645\u0641\u0642\u0648\u062f\u0629.<\/p>\n

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\u0648\u064a\u0645\u0644\u0623 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0647\u0630\u0647 \u0627\u0644\u0641\u062c\u0648\u0629. \u0648\u064a\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u0646\u0638\u0627\u0645 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u062d\u0631\u0631 \u0631\u0626\u064a\u0633\u064a \u0648\u0627\u062b\u0646\u064a\u0646 \u0645\u0646 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0631\u064a\u0628\u064a \u0644\u062f\u0644\u064a\u0644 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u060c \u0648\u0627\u0644\u062a\u064a \u062a\u0648\u062c\u0647 \u0622\u0644\u0627\u062a \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0648\u062a\u0631\u0645\u064a\u0632 \u0627\u0644\u062a\u0639\u062f\u064a\u0644\u0627\u062a. \u0648\u064a\u0648\u062c\u0647 \u0643\u0644\u0627 \u0627\u0644\u062d\u0645\u0636\u064a\u0646 \u0627\u0644\u0646\u0648\u0648\u064a\u0646 \u0627\u0644\u0631\u064a\u0628\u064a\u064a\u0646 \u0627\u0644\u062f\u0644\u064a\u0644\u064a\u064a\u0646 \u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0644\u0639\u0645\u0644 \u0634\u0642 \u0648\u0627\u062d\u062f \u0645\u062a\u0642\u0637\u0639 \u0641\u064a \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0641\u064a \u0645\u0648\u0627\u0642\u0639 \u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0645\u062e\u062a\u0644\u0641\u0629 \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0648\u0645\u060c \u0645\u062a\u062c\u0646\u0628\u064b\u0627 \u0647\u0630\u0627 \u0627\u0644\u0646\u0648\u0639 \u0645\u0646 \u0643\u0633\u0631 \u0627\u0644\u0634\u0631\u064a\u0637 \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0627\u0644\u0630\u064a \u064a\u062e\u0644\u0642 \u0645\u0646\u062a\u062c\u0627\u062a \u062b\u0627\u0646\u0648\u064a\u0629 \u063a\u064a\u0631 \u0645\u0631\u063a\u0648\u0628 \u0641\u064a\u0647\u0627 \u0628\u0637\u0631\u0642 \u0623\u062e\u0631\u0649. \u062b\u0645 \u064a\u0642\u0648\u0645 \u0627\u0644\u0646\u0638\u0627\u0645 \u0628\u062a\u0648\u0644\u064a\u0641 \u062e\u064a\u0648\u0637 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u062a\u0643\u0645\u064a\u0644\u064a\u0629 \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0627\u0644\u062a\u064a \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0627\u0644\u062a\u0633\u0644\u0633\u0644 \u0627\u0644\u0645\u0637\u0644\u0648\u0628 \u0628\u064a\u0646 \u0627\u0644\u0634\u0642\u0648\u0642. \u0648\u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0647\u0630\u0627 \u0627\u0644\u0646\u0647\u062c\u060c \u062a\u0645\u0643\u0646 \u0627\u0644\u0641\u0631\u064a\u0642 \u0645\u0646 \u0625\u062f\u0631\u0627\u062c \u0623\u0648 \u0627\u0633\u062a\u0628\u062f\u0627\u0644 \u0623\u0648 \u062d\u0630\u0641 \u062a\u0633\u0644\u0633\u0644\u0627\u062a \u064a\u0635\u0644 \u0637\u0648\u0644\u0647\u0627 \u0625\u0644\u0649 \u062d\u0648\u0627\u0644\u064a 800 \u0632\u0648\u062c \u0623\u0633\u0627\u0633\u064a.<\/p>\n

\u0648\u0644\u062a\u062d\u0631\u064a\u0631 \u062a\u0633\u0644\u0633\u0644\u0627\u062a \u0623\u0643\u0628\u0631\u060c \u0627\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0646\u0638\u0627\u0645 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0644\u062a\u062b\u0628\u064a\u062a “\u0645\u0648\u0627\u0642\u0639 \u0627\u0644\u0647\u0628\u0648\u0637” \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0648\u0645 \u0645\u0646 \u0623\u062c\u0644 \u0625\u0646\u0632\u064a\u0645\u0627\u062a \u062a\u0633\u0645\u0649 \u0645\u0639\u064a\u062f\u0627\u062a \u0627\u0644\u062a\u0631\u0643\u064a\u0628 (“\u0631\u064a\u0643\u0648\u0645\u0628\u064a\u0646\u0627\u064a\u0633\u064a\u0633” (recombinases) [\u0625\u0646\u0632\u064a\u0645 \u064a\u0639\u0632\u0632 \u0627\u0644\u062a\u0631\u0643\u064a\u0628 \u0627\u0644\u062c\u064a\u0646\u064a] \u0627\u0644\u062e\u0627\u0635\u0629 \u0628\u0627\u0644\u0645\u0648\u0642\u0639\u060c \u0648\u0627\u0644\u062a\u064a \u062a\u062d\u0641\u0632 \u062a\u0643\u0627\u0645\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0641\u064a \u0645\u0648\u0627\u0642\u0639 \u0645\u062d\u062f\u062f\u0629 \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0648\u0645. \u062b\u0645 \u0639\u0627\u0644\u062c \u0627\u0644\u0641\u0631\u064a\u0642 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0628\u0625\u0646\u0632\u064a\u0645 “\u0645\u0639\u064a\u062f \u0627\u0644\u062a\u0631\u0643\u064a\u0628” \u0648\u0642\u062f\u0645 \u0627\u0644\u0642\u0637\u0639 \u0627\u0644\u0637\u0648\u064a\u0644\u0629 \u0645\u0646 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u062a\u064a \u0623\u0631\u0627\u062f\u0648\u0627 \u0625\u062f\u062e\u0627\u0644\u0647\u0627 \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0648\u0645. \u0648\u0642\u062f \u0633\u0645\u062d \u0627\u0644\u062c\u0645\u0639 \u0628\u064a\u0646 \u0625\u0646\u0632\u064a\u0645\u0627\u062a \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0623\u0648\u0644\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0648”\u0645\u0639\u064a\u062f\u0627\u062a \u0627\u0644\u062a\u0631\u0643\u064a\u0628” \u0644\u0644\u0639\u0644\u0645\u0627\u0621 \u0628\u062a\u062d\u0631\u064a\u0631 \u062a\u0633\u0644\u0633\u0644\u0627\u062a \u0627\u0644\u0622\u0644\u0627\u0641 \u0645\u0646 \u0627\u0644\u0623\u0632\u0648\u0627\u062c \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 – \u0628\u0637\u0648\u0644 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0628\u0623\u0643\u0645\u0644\u0647\u0627.<\/p>\n

\u0648\u064a\u062e\u062a\u0628\u0631 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0644\u064a\u0648 \u0648\u0641\u0631\u064a\u0642\u0647 \u0627\u0644\u0622\u0646 “\u0645\u0639\u064a\u062f\u0627\u062a \u062a\u0631\u0643\u064a\u0628” \u0645\u062e\u062a\u0644\u0641\u0629 \u0627\u0644\u062a\u064a \u0642\u062f \u062a\u062c\u0639\u0644 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0623\u0648\u0644\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0623\u0643\u062b\u0631 \u0643\u0641\u0627\u0621\u0629. \u0643\u0645\u0627 \u064a\u0642\u0648\u0645\u0648\u0646 \u0628\u062a\u0642\u064a\u064a\u0645 \u0642\u062f\u0631\u0629 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0623\u0648\u0644\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c \u0639\u0644\u0649 \u062a\u062b\u0628\u064a\u062a \u062a\u0633\u0644\u0633\u0644\u0627\u062a \u0648\u0631\u0627\u062b\u064a\u0629 \u0623\u0637\u0648\u0644.<\/p>\n

\u0648\u0642\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u0641\u064a\u0633\u0648\u0631 \u0644\u064a\u0648: “\u0644\u0642\u062f \u0643\u0627\u0646 \u0637\u0645\u0648\u062d\u0627 \u0642\u062f\u064a\u0645\u0627 \u0644\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0645\u062e\u062a\u0628\u0631\u0646\u0627 \u0623\u0646 \u062a\u0643\u0648\u0646 \u0642\u0627\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0628\u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u062a\u064a \u0637\u0648\u0631 \u0628\u0647\u0627 \u0627\u0644\u0639\u0644\u0645\u0627\u0621 \u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0639\u0644\u0649 \u0645\u062f\u0649 \u0627\u0644\u0633\u0646\u0648\u0627\u062a \u0627\u0644\u0642\u0644\u064a\u0644\u0629 \u0627\u0644\u0645\u0627\u0636\u064a\u0629”. \u0648\u0623\u0636\u0627\u0641: “\u064a\u0645\u0643\u0646 \u0644\u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629\u060c \u062c\u0646\u0628\u0627 \u0625\u0644\u0649 \u062c\u0646\u0628 \u0645\u0639 \u0627\u0644\u062c\u0647\u0648\u062f \u0627\u0644\u0623\u062e\u0631\u0649 \u0644\u0639\u0644\u0645\u0627\u0621 \u0622\u062e\u0631\u064a\u0646\u060c \u0623\u0646 \u062a\u0645\u062b\u0644 \u0628\u062f\u0627\u064a\u0627\u062a \u062c\u064a\u0644 \u062c\u062f\u064a\u062f \u0645\u0646 \u0627\u0633\u062a\u0631\u0627\u062a\u064a\u062c\u064a\u0627\u062a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a\u060c \u062a\u0645\u0627\u0645\u0627 \u0643\u0645\u0627 \u0645\u062b\u0644\u062a \u0646\u0648\u0643\u0644\u064a\u0627\u0632\u0627\u062a \u0643\u0631\u064a\u0633\u0628\u0631 (CRISPR) [\u0627\u0644\u0646\u0648\u0643\u0644\u064a\u0627\u0632\u0627\u062a \u0647\u064a \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0625\u0646\u0632\u064a\u0645 \u064a\u0634\u0642 \u0633\u0644\u0627\u0633\u0644 \u0627\u0644\u0646\u064a\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f\u0627\u062a \u0641\u064a \u0627\u0644\u0623\u062d\u0645\u0627\u0636 \u0627\u0644\u0646\u0648\u0648\u064a\u0629 \u0627\u0644\u0649 \u0648\u062d\u062f\u0627\u062a] \u0648\u0627\u0644\u0645\u062d\u0631\u0631\u064a\u0646 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u064a\u0646 \u0648\u0627\u0644\u0645\u062d\u0631\u0631\u064a\u0646 \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u064a\u0646 \u0628\u062f\u0627\u064a\u0627\u062a \u062c\u064a\u0644 \u062c\u062f\u064a\u062f \u0645\u0646 \u062a\u0642\u0646\u064a\u0627\u062a \u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u0627\u062a”.<\/p>\n

*\u062a\u0645\u062a \u0627\u0644\u062a\u0631\u062c\u0645\u0629 \u0628\u062a\u0635\u0631\u0641<\/span><\/p>\n

\u0627\u0644\u0645\u0635\u062f\u0631:<\/strong><\/p>\n

https:\/\/phys.org\/news\/2021-12-prime-inserts-entire-genes-human.html<\/a><\/p>\n

\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a:<\/strong> \u0623\u0646\u062f\u0631\u0648 \u06a4\u064a \u0623\u0646\u0632\u0627\u0644\u0648\u0646 \u0648\u0622\u062e\u0631\u0648\u0646\u060c Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing,\u00a0Nature Biotechnology\u00a0(2021).\u00a0DOI: 10.1038\/s41587-021-01133-w<\/a><\/span><\/p>\n[\u0661] \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0647\u0646\u062a\u0631 \u0647\u064a \u0627\u0636\u0637\u0631\u0627\u0628 \u0646\u0627\u062f\u0631 \u0648\u0631\u0627\u062b\u064a \u0644\u0627 \u064a\u0647\u0636\u0645 \u0641\u064a\u0647 \u0627\u0644\u062c\u0633\u0645 (\u064a\u0643\u0633\u0631) \u062c\u0632\u064a\u0626\u0627\u062a \u0627\u0644\u0633\u0643\u0631 \u0628\u0634\u0643\u0644 \u0635\u062d\u064a\u062d \u0641\u064a \u0627\u0644\u062c\u0633\u0645. \u0639\u0646\u062f\u0645\u0627 \u062a\u062a\u0631\u0627\u0643\u0645 \u0647\u0630\u0647 \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a \u0641\u064a \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0648\u0627\u0644\u0623\u0646\u0633\u062c\u0629 \u0628\u0645\u0631\u0648\u0631 \u0627\u0644\u0648\u0642\u062a\u060c \u0641\u0625\u0646\u0647\u0627 \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0633\u0628\u0628 \u0636\u0631\u0631\u0627 \u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0646\u0645\u0648 \u0648\u0627\u0644\u0642\u062f\u0631\u0627\u062a \u0627\u0644\u0628\u062f\u0646\u064a\u0629 \u0648\u0627\u0644\u0639\u0642\u0644\u064a\u0629. \u064a\u062d\u062f\u062b \u0627\u0644\u0627\u0636\u0637\u0631\u0627\u0628 \u062f\u0627\u0626\u0645\u0627 \u062a\u0642\u0631\u064a\u0628\u0627 \u0639\u0646\u062f \u0627\u0644\u0623\u0648\u0644\u0627\u062f. \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0647\u0646\u062a\u0631 \u0647\u064a \u0648\u0627\u062d\u062f\u0629 \u0645\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u062a\u0633\u0645\u0649 \u0639\u062f\u064a\u062f \u0627\u0644\u0633\u0643\u0627\u0631\u064a\u062f \u0627\u0644\u0645\u062e\u0627\u0637\u064a. \u0648\u064a\u0639\u0631\u0641 \u0623\u064a\u0636\u0627 \u0628\u0627\u0633\u0645 \u0639\u062f\u064a\u062f \u0627\u0644\u0633\u0643\u0627\u0631\u064a\u062f \u0627\u0644\u0645\u062e\u0627\u0637\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a. \u064a\u062a\u0645 \u062a\u0634\u062e\u064a\u0635 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0647\u0646\u062a\u0631 \u062f\u0627\u0626\u0645\u0627 \u062a\u0642\u0631\u064a\u0628\u0627 \u0639\u0646\u062f \u0627\u0644\u0630\u0643\u0648\u0631. \u064a\u0634\u062e\u0635\u0647 \u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0641\u064a \u0645\u0627 \u064a\u0642\u0631\u0628 \u0645\u0646 1 \u0645\u0646 \u0623\u0635\u0644 100000 \u0625\u0644\u0649 170000 \u0630\u0643\u0631. \u0648\u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u0643\u0648\u0646 \u0627\u0644\u0625\u0646\u0627\u062b \u062d\u0627\u0645\u0644\u0627\u062a \u0644\u0644\u0637\u0641\u0631\u0629 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0633\u0628\u0628 \u0639\u062f\u064a\u062f \u0627\u0644\u0633\u0643\u0627\u0631\u064a\u062f \u0627\u0644\u0645\u062e\u0627\u0637\u064a \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a. \u0627\u0644\u0645\u0635\u062f\u0631: https:\/\/my.clevelandclinic.org\/health\/diseases\/17932-hunter-syndrome<\/p>\n

\"\"
\u0627\u0644\u0645\u0647\u0646\u062f\u0633 \u0645\u062d\u0645\u062f \u062c\u0648\u0627\u062f \u0622\u0644 \u0627\u0644\u0633\u064a\u062f \u0646\u0627\u0635\u0631 \u0627\u0644\u062e\u0636\u0631\u0627\u0648\u064a<\/span><\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

New prime editing system inserts entire genes in human cells \u00a0(Allessandra Dicorato – \u0627\u0644\u064a\u0633\u0627\u0646\u062f\u0631\u0627 \u062f\u064a\u0643\u0648\u0631\u0627\u062a\u0648) \u0645\u0644\u062e\u0635 \u0627\u0644\u0645\u0642\u0627\u0644\u0629: \u0637\u0648\u0631 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a \u0645\u0639\u0647\u062f “\u0628\u0631\u0648\u062f” (Broad Institute) \u0627\u0644\u062a\u0627\u0628\u0639 \u0644\u0645\u0639\u0647\u062f \u0645\u0627\u0633\u0627\u062a\u0634\u0648\u0633\u062a\u0633 \u0644\u0644\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0627 (MIT) \u0648\u062c\u0627\u0645\u0639\u0629 \u0647\u0627\u0631\u0641\u0627\u0631\u062f \u0646\u0633\u062e\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a (\u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0646\u0648\u0648\u064a \u0627\u0644\u0645\u0632\u062f\u0648\u062c) \u064a\u0645\u0643\u0646\u0647\u0627 \u062a\u062b\u0628\u064a\u062a \u0623\u0648 \u062a\u0628\u062f\u064a\u0644 \u062a\u0633\u0644\u0633\u0644 \u0627\u0644\u062d\u0645\u0636 \u0627\u0644\u0646\u0648\u0648\u064a \u0628\u062d\u062c\u0645 \u0627\u0644\u062c\u064a\u0646\u0627\u062a. \u0648\u0642\u062f \u062a\u0645 \u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u062a\u062d\u0631\u064a\u0631 \u0627\u0644\u0631\u0626\u064a\u0633\u064a \u0644\u0623\u0648\u0644 \u0645\u0631\u0629 …<\/p>\n","protected":false},"author":4,"featured_media":14240,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[19],"tags":[],"class_list":["post-14238","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-19"],"_links":{"self":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/14238","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14238"}],"version-history":[{"count":1,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/14238\/revisions"}],"predecessor-version":[{"id":14241,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/14238\/revisions\/14241"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/media\/14240"}],"wp:attachment":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}