{"id":10384,"date":"2021-04-25T21:32:13","date_gmt":"2021-04-25T18:32:13","guid":{"rendered":"https:\/\/www.qatifscience.com\/?p=10384"},"modified":"2021-04-25T21:32:13","modified_gmt":"2021-04-25T18:32:13","slug":"%d8%a7%d8%b3%d8%aa%d8%b9%d8%b1%d8%a7%d8%b6-%d9%84%d8%aa%d8%b7%d9%88%d8%b1-%d9%81%d9%8a%d8%b1%d9%88%d8%b3-%d8%b3%d8%a7%d8%b1%d8%b3-%d9%83%d9%88%d9%81-2-%d8%a8%d8%b9%d8%af-%d8%b9%d8%a7%d9%85-%d8%b9","status":"publish","type":"post","link":"https:\/\/www.qatifscience.com\/?p=10384","title":{"rendered":"\u0627\u0633\u062a\u0639\u0631\u0627\u0636 \u0644\u062a\u0637\u0648\u0631 \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0628\u0639\u062f \u0639\u0627\u0645 \u0639\u0644\u0649 \u0638\u0647\u0648\u0631\u0647 – \u062a\u0631\u062c\u0645\u0629 \u0639\u062f\u0646\u0627\u0646 \u0623\u062d\u0645\u062f \u0627\u0644\u062d\u0627\u062c\u064a"},"content":{"rendered":"

One year of SARS-CoV-2 evolution
\n(\u062c\u0645\u0639\u064a\u0629 \u0639\u0644\u0645 \u0627\u0644\u0623\u062d\u064a\u0627\u0621 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 – Microbiology Society)<\/span><\/h2>\n

\"\"\u0646\u0634\u0631 \u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a 15 \u0623\u0628\u0631\u064a\u0644 2021 \u0645\u0631\u0627\u062c\u0639\u0629 \u0641\u0627\u062d\u0635\u0629 \u0648\u0634\u0627\u0645\u0644\u0629 \u0639\u0646 \u0637\u0641\u0631\u0627\u062a \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0627\u0644\u062a\u064a \u062d\u062f\u062b\u062a \u062e\u0644\u0627\u0644 \u0627\u0644\u0639\u0627\u0645 \u0627\u0644\u0645\u0627\u0636\u064a (1) \u0641\u064a \u0645\u062c\u0644\u0629 \u0639\u0644\u0645 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u0639\u0627\u0645 (General Virology) (\u0627\u0646\u0638\u0631 2). \u00a0\u0647\u0630\u0627 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u062a\u0646\u0627\u0642\u0634 \u0646\u062a\u0627\u0626\u062c \u0623\u0643\u062b\u0631 \u0645\u0646 180 \u062f\u0631\u0627\u0633\u0629 \u0628\u062d\u062b\u064a\u0629 \u0646\u0634\u0631\u062a \u0633\u0627\u0628\u0642\u064b\u0627 \u0648\u062a\u062a\u0628\u0639 \u0627\u0644\u062a\u063a\u064a\u064a\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u062d\u062f\u062b\u062a \u0641\u064a \u062c\u064a\u0646\u0648\u0645 \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0648\u0645\u062a\u063a\u064a\u0631\u0627\u062a\u0647 (\u0645\u062a\u062d\u0648\u0631\u0627\u062a\u0647 variants) \u0627\u0644\u062a\u064a \u062d\u062f\u062b\u062a \u0646\u062a\u064a\u062c\u0629 \u0644\u0630\u0644\u0643.<\/p>\n

\u0638\u0647\u0631\u062a \u0623\u0639\u062f\u0627\u062f \u0645\u0646 \u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0645\u0646 \u062d\u0648\u0627\u0636\u0646 (\u0623\u0634\u062e\u0627\u0635) \u0636\u0639\u064a\u0641\u0629 (\u0646\u0627\u0642\u0635\u0629) \u0627\u0644\u0645\u0646\u0627\u0639\u0629 (immunocompromised)\u060c \u0627\u0644\u062a\u064a \u062a\u0639\u0631\u0641\u062a \u0639\u0644\u064a\u0647\u0627 \u0647\u0630\u0647 \u0627\u0644\u0628\u062d\u0648\u062b. \u064a\u064f\u0639\u062a\u0642\u062f \u0623\u0646 \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0627\u0644\u0645\u062b\u064a\u0631\u0629 \u0644\u0644\u0642\u0644\u0642 – \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u0627\u0644\u0645\u062a\u062d\u0648\u0631 \u0627\u0644\u0630\u064a \u064a\u062d\u0648\u064a \u0627\u0644\u0637\u0641\u0631\u0629 B.1.1.7 \u060c \u0648\u0647\u0648 \u0645\u062a\u062d\u0648\u0631 \u062a\u0645 \u0627\u0644\u062a\u0639\u0631\u0641 \u0639\u0644\u064a\u0647 \u0623\u0648\u0644 \u0645\u0631\u0629 \u0641\u064a \u0645\u0642\u0627\u0637\u0639\u0629 \u0643\u064a\u0646\u062a (Kent) \u0641\u064a \u062c\u0646\u0648\u0628 \u0634\u0631\u0642 \u0627\u0646\u062c\u0644\u062a\u0631\u0627 – \u0643\u0627\u0646\u062a \u0646\u062a\u064a\u062c\u0629 \u0639\u062f\u0648\u0649 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f \u0644\u062f\u0649 \u0623\u0634\u062e\u0627\u0635 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0636\u0639\u0641 (\u0646\u0642\u0635) \u0641\u064a \u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u0629.<\/p>\n

\u0627\u0644\u0639\u062f\u0648\u0649 \u0627\u0644\u0645\u0633\u062a\u0645\u0631\u0629 \u0641\u064a \u0627\u0644\u062d\u0648\u0627\u0636\u0646 (\u0627\u0644\u0623\u0634\u062e\u0627\u0635) \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0636\u0639\u0641 \/ \u0646\u0642\u0635 \u0641\u064a \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u062a\u0633\u0628\u0628 \u0641\u064a \u062a\u062d\u0648\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0628\u0648\u062a\u064a\u0631\u0629 \u0645\u062a\u0632\u0627\u064a\u062f\u0629 \u0644\u0623\u0646 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0634\u062e\u0635 \u0644\u0627 \u064a\u0633\u062a\u0637\u064a\u0639 \u0627\u0644\u0642\u0636\u0627\u0621 \u0639\u0644\u0649 \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0628\u0627\u0644\u0633\u0631\u0639\u0629 \u0627\u0644\u062a\u064a \u064a\u062a\u0645\u0643\u0646 \u0628\u0647\u0627 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0634\u062e\u0635 \u0627\u0644\u0633\u0644\u064a\u0645.<\/p>\n

\u0634\u0631\u062d \u0645\u0624\u0644\u0641\u0648 \u0648\u0631\u0642\u0629 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u0628\u0631\u0648\u0641\u0633\u0648\u0631 \u0648\u064a\u0646\u062f\u064a \u0628\u0627\u0631\u0643\u0644\u064a (Wendy Barclay)\u060c \u0648\u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u062a\u0648\u0645\u0627\u0633 \u0628\u064a\u0643\u0648\u0643 (Thomas Peacock)\u060c \u0648\u0627\u0644\u0628\u0631\u0648\u0641\u0633\u0648\u0631 \u062c\u0648\u0644\u064a\u0627\u0646 \u0647\u064a\u0633\u0643\u0648\u0643\u0633\u00a0(Julian Hiscox)\u060c \u0648\u0631\u064a\u0628\u064a\u0643\u0627 \u0628\u0646\u0631\u064a\u0633 \u0631\u0627\u0646\u062f\u0627\u0644 (Rebekah Penrice-Randal) \u0623\u0647\u0645\u064a\u0629 \u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0641\u064a \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0628\u063a\u0631\u0636 \u0627\u0644\u0633\u064a\u0637\u0631\u0629 \u0639\u0644\u064a\u0647 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644: “\u0648\u0628\u0638\u0647\u0648\u0631 \u0627\u0644\u0645\u0632\u064a\u062f \u0648\u0627\u0644\u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \/ \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0644\u0647\u0630\u0627 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u060c \u0633\u0646\u062d\u0635\u0644 \u0639\u0644\u0649 \u0635\u0648\u0631\u0629 \u00a0\u0623\u0641\u0636\u0644 \u0639\u0646 \u0623\u0648\u062c\u0647 \u0627\u0644\u062a\u0634\u0627\u0628\u0647 \u0648\u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641 \u0627\u0644\u0645\u0634\u062a\u0631\u0643\u0629 \u0628\u064a\u0646\u0647\u0627 \u0648\u064a\u0645\u0643\u0646 \u0623\u0646 \u0646\u062a\u0646\u0628\u0623 \u0628\u0634\u0643\u0644 \u0623\u0641\u0636\u0644 \u0628\u0645\u0627 \u0633\u062a\u0628\u062f\u0648 \u0639\u0644\u064a\u0647 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \/ \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0627\u0644\u0623\u062e\u0631\u0649. \u0648\u0636\u0639 \u0643\u0644 \u0647\u0630\u0647 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0645\u0639\u064b\u0627 \u0633\u064a\u0633\u0627\u0639\u062f\u0646\u0627 \u0623\u064a\u0636\u064b\u0627 \u0641\u064a \u062a\u0635\u0645\u064a\u0645 \u0644\u0642\u0627\u062d\u0627\u062a \u0645\u0639\u0632\u0632\u0629 (3) \u062a\u0642\u064a \u0636\u062f \u0623\u0643\u0628\u0631 \u0639\u062f\u062f \u0645\u0645\u0643\u0646 \u0645\u0646 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \/ \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0623\u0648 \u0641\u064a \u062a\u0635\u0645\u064a\u0645 \u0641\u062d\u0648\u0635\u0627\u062a \u062a\u0634\u062e\u064a\u0635\u064a\u0629 \u0645\u0633\u062a\u0647\u062f\u0641\u0629”.<\/p>\n

\"\"
Creative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIH<\/span><\/figcaption><\/figure>\n

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\u0637\u0641\u0631\u0627\u062a \u062d\u0633\u0643\u0627\u062a \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a\u0629 \u0627\u0644\u062a\u064a \u0644\u0647\u0627 \u062f\u0644\u0627\u0644\u0629 \u0627\u062d\u0635\u0627\u0626\u064a\u0629 \u0627\u0644\u062a\u064a \u0646\u0648\u0642\u0634\u062a \u0641\u064a \u0648\u0631\u0642\u0629 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \/ \u0627\u0644\u0627\u0633\u062a\u0639\u0631\u0627\u0636 \u0647\u064a \u0643\u0645\u0627 \u064a\u0644\u064a:<\/strong><\/p>\n

\u0645\u062a\u062d\u0648\u0631\u00a0<\/strong>D614G<\/strong>:<\/strong><\/p>\n

\u0641\u064a \u0641\u0628\u0631\u0627\u064a\u0631 2020\u060c \u0627\u0643\u062a\u0634\u0641\u062a \u0637\u0641\u0631\u0629 \u0641\u064a \u0627\u0644\u062d\u0633\u0643\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u0629 \u0644\u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0648\u0633\u064f\u0645\u064a\u062a \u0628\u0645\u062a\u062d\u0648\u0631 D614G. \u0648\u0648\u062c\u062f \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0629 \u062a\u062c\u0639\u0644 \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0645\u0639\u062f\u064d \u0623\u0643\u062b\u0631\u060c \u0625\u0644\u0627 \u0623\u0646\u0647\u0627 \u0644\u0627 \u062a\u062c\u0639\u0644\u0647 \u0623\u0643\u062b\u0631 \u0636\u0631\u0631\u064b\u0627. \u0647\u0630\u0647 \u0627\u0644\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0627\u0644\u0639\u062f\u0648\u0649 \u0623\u062f\u062a \u0625\u0644\u0649 \u0645\u064a\u0632\u0629 \u0644\u064a\u0627\u0642\u0629 \u0643\u0628\u064a\u0631\u0629 \u0644\u0644\u0641\u064a\u0631\u0648\u0633\u060c \u00a0\u0648\u0641\u064a \u063a\u0636\u0648\u0646 \u0623\u0631\u0628\u0639\u0629 \u0623\u0634\u0647\u0631\u060c \u0627\u0643\u062a\u064f\u0634\u0641 \u0623\u0646 80\u066a \u0645\u0646 \u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0627\u0644\u062a\u064a \u0639\u064f\u0645\u0644 \u0644\u0647\u0627 \u062a\u0633\u0644\u0633\u0644 \u062c\u064a\u0646\u0648\u0645\u064a \u062d\u0648\u0644 \u0627\u0644\u0639\u0627\u0644\u0645 \u0644\u0647\u0627 \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0629. \u0627\u0644\u0622\u0646 \u060c \u0623\u062c\u0632\u0627\u0621 \u0641\u0642\u0637 \u0645\u0646 \u0623\u0641\u0631\u064a\u0642\u064a\u0627 \u0644\u062f\u064a\u0647\u0627 \u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0645\u0646\u062a\u0634\u0631\u0629 \u0644\u064a\u0633 \u0644\u0647\u0627 \u0637\u0641\u0631\u0629 D614G.<\/p>\n

\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0627\u0644\u0645\u062e\u0627\u0648\u0641 \u0627\u0644\u0623\u0648\u0644\u064a\u0629\u060c \u0641\u0625\u0646 \u0645\u062a\u062d\u0648\u0631 D614G \u0644\u064a\u0633 \u0644\u0647 \u062a\u0623\u062b\u064a\u0631 \u0639\u0644\u0649 \u0643\u0641\u0627\u0621\u0629 \/ \u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0644\u0642\u0627\u062d \u0648\u0641\u064a \u0628\u0639\u0636 \u0627\u0644\u062d\u0627\u0644\u0627\u062a\u060c \u062a\u0642\u0636\u064a \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0644\u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0639\u0644\u0649 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u062a\u064a \u0644\u0647\u0627 \u0637\u0641\u0631\u0629 D614G \u0628\u0633\u0647\u0648\u0644\u0629 \u0643\u0628\u064a\u0631\u0629.<\/p>\n

\u0637\u0641\u0631\u0629\u00a0<\/strong>Y435F:<\/strong><\/p>\n

\u0641\u064a \u0645\u0646\u062a\u0635\u0641 \u0639\u0627\u0645 2020\u060c \u0623\u0635\u0628\u062d\u062a \u0627\u0644\u062a\u0642\u0627\u0631\u064a\u0631 \u0627\u0644\u062a\u064a \u0623\u0641\u0627\u062f\u062a \u0639\u0646 \u0625\u0635\u0627\u0628\u0629 \u0627\u0644\u0645\u0646\u0643 (mink) (\u062d\u064a\u0648\u0627\u0646 \u062b\u062f\u064a\u064a \u0644\u0627\u062d\u0645) \u0628\u0627\u0644\u0639\u062f\u0648\u0649 \u0645\u0646 \u0627\u0644\u0628\u0634\u0631 \u062a\u0642\u0627\u0631\u064a\u0631 \u0645\u062a\u0643\u0631\u0631\u0629. \u0641\u064a \u062d\u064a\u0648\u0627\u0646 \u0627\u0644\u0645\u0646\u0643 \u060c \u0637\u0648\u0631\u062a \u062d\u0633\u0643\u0627\u062a \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a\u0629 \u0637\u0641\u0631\u062a\u064a\u0646 \u0628\u0634\u0643\u0644 \u0645\u062a\u0643\u0631\u0631\u060c \u062a\u062f\u0639\u0649 \u0647\u0627\u062a\u064a\u0646 \u0627\u0644\u0637\u0641\u0631\u062a\u064a\u0646 \u0628 Y435F \u0648 N501T. \u062a\u0633\u0645\u062d \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0628\u0627\u0631\u062a\u0628\u0627\u0637 \u0623\u0642\u0648\u0649 \u0644\u0644\u0641\u064a\u0631\u0648\u0633 \u0628\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0650\u0644 (receptor) \u0641\u064a \u0627\u0644\u0628\u0634\u0631. \u0647\u0630\u0647 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0628\u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0643\u062a\u0634\u0641\u062a \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 \u0627\u0644\u0646\u0627\u0633 \u0645\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0639\u062f\u0648\u0649 \u0641\u064a \u0627\u0644\u062f\u0646\u0645\u0627\u0631\u0643\u060c \u0648\u064a\u0639\u062a\u0642\u062f \u0623\u0646\u0647\u0627 \u0627\u0646\u062a\u0642\u0644\u062a \u0644\u0647\u0645 \u0645\u0646 \u062d\u064a\u0648\u0627\u0646 \u0627\u0644\u0645\u0646\u0643. \u0648\u0645\u0645\u0627 \u064a\u062b\u064a\u0631 \u0627\u0644\u0642\u0644\u0642\u060c \u0623\u0646 \u0644\u0647\u0630\u0627 \u0627\u0644\u0645\u062a\u062d\u0648\u0631 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0625\u0635\u0627\u0628\u0629 \u0627\u0644\u0630\u064a\u0646 \u0623\u0635\u064a\u0628\u0648\u0627 \u0633\u0627\u0628\u0642\u064b\u0627 \u0628\u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u062d\u064a\u062b \u0643\u0627\u0646 \u064a\u064f\u0639\u062a\u0642\u062f \u0623\u0646 \u0644\u062f\u064a\u0647\u0627 (\u062d\u064a\u0648\u0627\u0646 \u0627\u0644\u0645\u0646\u0643) \u0628\u0639\u0636 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0636\u062f \u0627\u0644\u0641\u064a\u0631\u0648\u0633. \u0648\u0646\u062a\u064a\u062c\u0629 \u0644\u0630\u0644\u0643 \u060c \u062a\u0645 \u0639\u0632\u0644 17 \u0645\u0644\u064a\u0648\u0646 \u0645\u0646 \u062d\u064a\u0648\u0627\u0646 \u0627\u0644\u0645\u0646\u0643.<\/p>\n

\u0641\u0642\u062f \u0623\u0641\u064a\u062f \u0639\u0646 \u0638\u0647\u0648\u0631 \u0637\u0641\u0631\u0629\u00a0Y435F\u00a0\u0641\u064a \u0645\u0646 \u064a\u0639\u0627\u0646\u064a \u0645\u0646 \u0636\u0639\u0641 \/ \u0646\u0642\u0635 \u0641\u064a \u0627\u0644\u0645\u0646\u0627\u0639\u0629\u060c \u0631\u0628\u0645\u0627 \u0646\u062a\u064a\u062c\u0629 \u0644\u0625\u0635\u0627\u0628\u0629 \u0645\u0632\u0645\u0646\u0629 \u0628\u0627\u0644\u0641\u064a\u0631\u0648\u0633\u060c \u00a0\u0645\u0645\u0627 \u0633\u0645\u062d \u0644\u0647 \u0628\u0627\u0644\u062a\u0643\u064a\u0641 \u0645\u0639\u0647.<\/p>\n

\u0637\u0641\u0631\u0629<\/strong>\u00a0N501Y<\/strong>:<\/strong><\/p>\n

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\u0648\u064f\u062c\u062f \u0623\u0646\u0647 \u0644\u064a\u0633 \u0647\u0646\u0627\u0643 \u062a\u0623\u062b\u064a\u0631 \u064a\u0630\u0643\u0631 \u0644\u0637\u0641\u0631\u0629\u00a0N501y\u00a0\u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u0648\u0627\u0644\u0627\u0635\u0627\u0628\u0627\u062a \u0628\u0627\u0644\u0639\u062f\u0648\u0649 \u0627\u0644\u0633\u0627\u0628\u0642\u0629.<\/p>\n

\"\"
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\u0637\u0641\u0631\u0629\u00a0<\/strong>E484K<\/strong>:<\/strong><\/p>\n

\u0637\u0641\u0631\u0629 \u0627\u0644\u062d\u0633\u0643\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a\u0629\u00a0E484K\u00a0\u0638\u0647\u0631\u062a \u0641\u064a \u0627\u0644\u0623\u0634\u0647\u0631 \u0627\u0644\u0623\u062e\u064a\u0631\u0629\u060c \u0645\u0631\u0629 \u0641\u064a \u062c\u0646\u0648\u0628 \u0625\u0641\u0631\u064a\u0642\u064a\u0627 \u0648\u0645\u0631\u062a\u064a\u0646 \u0639\u0644\u0649 \u0627\u0644\u0623\u0642\u0644 \u0641\u064a \u0627\u0644\u0628\u0631\u0627\u0632\u064a\u0644. \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u0644\u0647\u0627 \u0637\u0641\u0631\u0629\u00a0E484K\u00a0\u0642\u0627\u062f\u0631\u0629 \u0639\u0644\u0649 \u062a\u0641\u0627\u062f\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0643\u0644 \u0645\u0646 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0645\u062d\u0635\u0646\u064a\u0646 \u0648\u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0633\u0627\u0628\u0642\u064b\u0627.<\/p>\n

\u064a\u064f\u0639\u062a\u0642\u062f \u0623\u0646 \u0647\u0630\u0647 \u0627\u0644\u0637\u0641\u0631\u0629 \u0643\u0627\u0646\u062a \u0645\u062f\u0641\u0648\u0639\u0629 \u0628\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0639\u0627\u0644\u064a\u0629 \u0645\u0646 \u0645\u0646\u0627\u0639\u0629 \u0627\u0644\u0642\u0637\u064a\u0639\u060c \u0645\u0645\u0627 \u0623\u062f\u0649 \u0625\u0644\u0649 \u062d\u062f\u0648\u062b \u0637\u0641\u0631\u0627\u062a \u0641\u064a \u0627\u0644\u062d\u0633\u0643\u0627\u062a \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a\u0629 \u0644\u062a\u0641\u0627\u062f\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a. \u0641\u064a \u0627\u0644\u0628\u0631\u0627\u0632\u064a\u0644\u060c \u0643\u0627\u0646\u062a \u0647\u0646\u0627\u0643 \u0639\u062f\u062f \u0645\u0646 \u0627\u0644\u062a\u0642\u0627\u0631\u064a\u0631 \u0639\u0646 \u0625\u0635\u0627\u0628\u0629 \u0627\u0644\u0639\u0627\u0645\u0644\u064a\u0646 \u0641\u064a \u0645\u062c\u0627\u0644 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0648\u063a\u064a\u0631\u0647\u0645 \u0645\u0646 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0630\u064a\u0646 \u0644\u062f\u064a\u0647\u0645 \u0623\u062c\u0633\u0627\u0645 \u0645\u0636\u0627\u062f\u0629 \u0644\u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u00a0\u0628\u0637\u0641\u0631\u0629\u00a0E484K\u060c \u0645\u0645\u0627 \u064a\u062b\u064a\u0631 \u0645\u062e\u0627\u0648\u0641 \u0628\u0634\u0623\u0646 \u062d\u0645\u0627\u064a\u0629 \u0627\u0644\u0644\u0642\u0627\u062d \u0636\u062f \u0647\u0630\u0627 \u0627\u0644\u0645\u062a\u062d\u0648\u0631.<\/p>\n

\u0648\u0631\u0642\u0629 \u0627\u0644\u0627\u0633\u062a\u0639\u0631\u0627\u0636 \u0647\u0630\u0647 \u062a\u0646\u0627\u0648\u0644\u062a \u0628\u0627\u0644\u062a\u0641\u0635\u064a\u0644 \u0623\u064a\u0636\u064b\u0627 \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u062d\u062f\u062b \u062a\u063a\u064a\u064a\u0631\u0627\u062a \u0641\u064a \u0623\u062c\u0632\u0627\u0621 \u0623\u062e\u0631\u0649 \u0645\u0646 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u060c \u0645\u062b\u0644 \u0628\u0631\u0648\u062a\u064a\u0646 ORF8\u060c \u0648\u0647\u0648 \u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0635\u0627\u062d\u0628 [\u0627\u0644\u0645\u062a\u0631\u062c\u0645: \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u064a\u0633\u0627\u0639\u062f \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0639\u0644\u0649 \u0627\u0644\u0637\u064a \u0628\u0634\u0643\u0644 \u0645\u0644\u0627\u0626\u0645\u060c \u0643\u0645\u0627 \u0648\u0631\u062f \u0641\u064a 5] \u064a\u064f\u0639\u062a\u0642\u062f \u0623\u0646\u0647 \u064a\u062b\u0628\u0637 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0644\u0645\u0636\u064a\u0641 \/ \u0627\u0644\u062d\u0627\u0636\u0646. \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0646\u0637\u0648\u064a \u0639\u0644\u0649 \u062d\u0630\u0641 \u0641\u064a \u0627\u0644\u062c\u064a\u0646 (6) \u0627\u0644\u0630\u064a \u064a\u0634\u0641\u0631 \u0628\u0631\u0648\u062a\u064a\u0646 ORF8 \u062a\u0633\u0628\u0628 \u0645\u0631\u0636\u064b\u0627 \u0627\u0643\u0644\u064a\u0646\u064a\u0643\u064a\u064b\u0627 \u0623\u0642\u0644 \u062d\u062f\u0629 (\u0644\u062a\u0639\u0631\u064a\u0641 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0627\u0643\u0644\u064a\u0646\u064a\u0643\u064a\u060c \u0631\u0627\u062c\u0639 7).<\/p>\n

\u062f\u0639\u0627 \u0645\u0624\u0644\u0641\u0648 \u0648\u0631\u0642\u0629 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0625\u0644\u0649 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u062c\u0647\u0648\u062f \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0637\u0641\u0631\u0627\u062a \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2. \u062a\u0642\u0648\u0645 \u0627\u0644\u0645\u0645\u0644\u0643\u0629 \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0648\u0627\u0644\u062f\u0646\u0645\u0627\u0631\u0643 \u062d\u0627\u0644\u064a\u064b\u0627 \u0628\u0639\u0645\u0644 \u062a\u0633\u0644\u0633\u0644 \u062c\u064a\u0646\u0648\u0645\u064a \u0639\u0627\u0644\u064d \u0628\u0634\u0643\u0644 \u063a\u064a\u0631 \u0645\u062a\u0643\u0627\u0641\u064a\u0621 \u0644\u062c\u064a\u0646\u0648\u0645 \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2. \u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u0645\u0646\u062a\u0638\u0645\u0629 \u0644\u0644\u0641\u064a\u0631\u0648\u0633 \u062a\u0633\u0645\u062d \u0628\u0627\u0644\u062a\u0639\u0631\u0641 \u0627\u0644\u0645\u0628\u0643\u0631 \u0639\u0644\u0649 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \/ \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0648\u062a\u0633\u0645\u062d \u0644\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0628\u062a\u062d\u062f\u064a\u062f \u0627\u0644\u0637\u0641\u0631\u0627\u062a \u0627\u0644\u0645\u0642\u062a\u0631\u0646\u0629 \u0628\u0647\u0627.<\/p>\n

“\u0639\u0644\u0649 \u0627\u0644\u0631\u063a\u0645 \u0645\u0646 \u0623\u0646 \u0645\u0631\u0627\u0642\u0628\u0629 \u0627\u0644\u062c\u064a\u0646 \u0641\u064a \u0623\u0648\u0631\u0648\u0628\u0627 \u0648\u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629 \u0642\u0648\u064a \u0625\u0644\u0649 \u062d\u062f \u0645\u0627\u060c \u0625\u0644\u0627 \u0623\u0646\u0647 \u0623\u0635\u0628\u062d \u0645\u0646 \u0627\u0644\u0648\u0627\u0636\u062d \u0623\u0646 \u0647\u0646\u0627\u0643 \u0645\u0646\u0627\u0637\u0642 \u0643\u0628\u064a\u0631\u0629 \u0645\u0646 \u0627\u0644\u0639\u0627\u0644\u0645 \u0644\u064a\u0633 \u0644\u062f\u064a\u0646\u0627 \u0623\u064a \u0641\u0643\u0631\u0629 \u0628\u0628\u0633\u0627\u0637\u0629 \u0639\u0646 \u0627\u0644\u0645\u062a\u063a\u064a\u0631\u0627\u062a \/ \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0627\u0644\u0645\u0646\u062a\u0634\u0631\u0629 \u0641\u064a\u0647\u0627. \u0628\u062f\u0623\u062a \u0647\u0630\u0647 \u0627\u0644\u0645\u062a\u062d\u0648\u0631\u0627\u062a \u062a\u0638\u0647\u0631 \u0641\u064a \u0623\u0648\u0631\u0648\u0628\u0627 \u0639\u0644\u0649 \u0623\u0646\u0647\u0627 \u0641\u0627\u0634\u064a\u0627\u062a \u0622\u062a\u064a\u0629 \u0645\u0646 \u0627\u0644\u062e\u0627\u0631\u062c \u0623\u0648 \u0645\u0646 \u062f\u0627\u062e\u0644 \u0627\u0644\u0645\u062c\u062a\u0645\u0639 \u0646\u0641\u0633\u0647. \u0645\u0631\u0627\u0642\u0628\u0629 \u0648\u0627\u0633\u0639\u0629 \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u062f\u0648\u0644 \u0628\u0634\u0643\u0644 \u0623\u0641\u0636\u0644 \u0633\u062a\u0633\u0645\u062d \u0644\u0646\u0627 \u0628\u0625\u062c\u0631\u0627\u0621 \u062a\u0642\u064a\u064a\u0645 \u0623\u0641\u0636\u0644 \u0644\u0645\u062e\u0627\u0637\u0631 \u0645\u0627 \u0642\u062f \u062a\u0628\u062f\u0648 \u0639\u0644\u064a\u0647 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062a\u0627\u0644\u064a\u0629 \u0645\u0646 \u0627\u0644\u062c\u0627\u0626\u062d\u0629\u060c \u0643\u0645\u0627 \u0642\u0627\u0644 \u0627\u0644\u0645\u0624\u0644\u0641\u0648\u0646. “\u0625\u0630\u0627 \u0623\u0631\u062f\u0646\u0627 \u0645\u0631\u0627\u0642\u0628\u0629 \u0638\u0647\u0648\u0631 \u0648\u0627\u0646\u062a\u0634\u0627\u0631 \u0648\u0627\u0646\u062a\u0642\u0627\u0644 \/ [\u0627\u0633\u062a\u064a\u0631\u0627\u062f \u0645\u0646 \u0627\u0644\u062e\u0627\u0631\u062c] \u0645\u062a\u062d\u0648\u0631\u0627\u062a \u0645\u062d\u062a\u0645\u0644\u0629 \u062a\u062a\u0641\u0627\u062f\u0649 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a\u060c \u0639\u0644\u064a\u0646\u0627 \u0645\u0648\u0627\u0635\u0644\u0629 \u0647\u0630\u0627 \u0627\u0644\u062c\u0647\u062f \u0623\u0648 \u0627\u0644\u0645\u062e\u0627\u0637\u0631\u0629 \u0628\u0645\u0632\u064a\u062f \u0645\u0646 \u0645\u0648\u062c\u0627\u062a \u0627\u0644\u062c\u0627\u0626\u062d\u0629 \u0648\u0641\u0634\u0644 \u0627\u0644\u0644\u0642\u0627\u062d\u0627\u062a. \u0639\u0644\u0627\u0648\u0629 \u0639\u0644\u0649 \u0630\u0644\u0643 \u060c \u0641\u0625\u0646 \u0641\u0647\u0645 \u0627\u0644\u0648\u0628\u0627\u0626\u064a\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0644\u0644\u0641\u064a\u0631\u0648\u0633 \u0641\u064a \u0623\u0642\u0631\u0628 \u0641\u0631\u0635\u0629 \u0645\u0645\u0643\u0646\u0629 \u0633\u064a\u0633\u0645\u062d \u0644\u0646\u0627 \u0628\u062a\u0637\u0648\u064a\u0631 \u0644\u0642\u0627\u062d\u0627\u062a \u0645\u0639\u0632\u0632\u0629 \u0645\u062d\u062f\u062b\u0629 \u0628\u0633\u0631\u0639\u0629”.<\/p>\n

\u0642\u0627\u0644 \u0627\u0644\u0628\u0631\u0648\u0641\u0633\u0648\u0631 \u0622\u0644\u0627\u0646 \u0643\u0648\u0644 (Alain Kohl)\u060c \u0646\u0627\u0626\u0628 \u0631\u0626\u064a\u0633 \u062a\u062d\u0631\u064a\u0631 \u0645\u062c\u0644\u0629 \u0639\u0644\u0645 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u0639\u0627\u0645\u0629 (General Virology): “\u0625\u0646 \u0638\u0647\u0648\u0631 \u0645\u062a\u063a\u064a\u0631\u0627\u062a \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0647\u0648 \u0623\u062d\u062f \u0627\u0644\u062a\u062d\u062f\u064a\u0627\u062a \u0627\u0644\u0643\u0628\u0631\u0649 \u0641\u064a \u0627\u0644\u062c\u0627\u0626\u062d\u0629 \u0627\u0644\u0642\u0627\u0626\u0645\u0629. \u0648\u0631\u0642\u0629 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \/ \u0627\u0644\u0627\u0633\u062a\u0639\u0631\u0627\u0636 \u0647\u0630\u0647 \u062a\u0644\u062e\u0635 \u0645\u0639\u0631\u0641\u062a\u0646\u0627 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0648\u0641\u0647\u0645\u0646\u0627 \u0644\u062a\u0637\u0648\u0631 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u060c \u0648\u0643\u0630\u0644\u0643 \u0627\u0644\u0639\u0648\u0627\u0642\u0628 – \u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644 \u0645\u0646 \u062d\u064a\u062b \u0627\u0644\u062a\u0637\u0639\u064a\u0645. \u0647\u0630\u0647 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0644\u0647\u0627 \u0623\u0647\u0645\u064a\u0629 \u0643\u0628\u064a\u0631\u0629 \u0644\u0623\u064a \u0634\u062e\u0635 \u064a\u0631\u063a\u0628 \u0641\u064a \u0645\u0639\u0631\u0641\u0629 \u0627\u0644\u0645\u0632\u064a\u062f \u0639\u0646 \u062a\u0627\u0631\u064a\u062e \u0647\u0630\u0627 \u0627\u0644\u0641\u064a\u0631\u0648\u0633 \u0648\u0645\u0627 \u0642\u062f \u064a\u062e\u0628\u0626\u0647 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u0644\u0646\u0627”.<\/p>\n

\u0645\u0635\u0627\u062f\u0631 \u0645\u0646 \u062f\u0627\u062e\u0644 \u0648\u062e\u0627\u0631\u062c \u0627\u0644\u0646\u0635:<\/strong><\/p>\n

1-\u00a0https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/jgv.0.001584<\/a><\/p>\n

2-\u00a0https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv<\/a><\/p>\n

3-\u00a0https:\/\/ar.wikipedia.org\/wiki\/\u062c\u0631\u0639\u0629_\u0645\u0639\u0632\u0632\u0629<\/a><\/p>\n

4-\u00a0https:\/\/ib.bioninja.com.au\/standard-level\/topic-5-evolution-and-biodi\/52-natural-selection\/selection-pressures.html<\/a><\/p>\n

5-\u00a0https:\/\/www.genscript.com\/molecular-biology-glossary\/8277\/accessory-protein<\/a><\/p>\n

6-\u00a0\u00a0“\u0641\u064a\u00a0\u0639\u0644\u0645 \u0627\u0644\u0648\u0631\u0627\u062b\u0629<\/a>\u060c\u00a0\u0627\u0644\u062d\u0630\u0641\u00a0\u0623\u0648\u00a0\u0637\u0641\u0631\u0629 \u0627\u0644\u062d\u0630\u0641\u00a0\u0623\u0648\u00a0\u0627\u0644\u062e\u0628\u0646\u00a0(\u0628\u0627\u0644\u0625\u0646\u062c\u0644\u064a\u0632\u064a\u0629<\/a>:\u00a0deletion)\u200f (\u0627\u0644\u0631\u0645\u0632:\u0394) \u0647\u0648\u00a0\u0637\u0641\u0631\u0629<\/a>\u00a0\u064a\u062d\u0630\u0641 \u0641\u064a\u0647\u0627 \u062c\u0632\u0621 \u0645\u0646\u00a0\u0627\u0644\u0643\u0631\u0648\u0645\u0648\u0633\u0648\u0645<\/a>\u00a0\u0623\u0648 \u062a\u0633\u0644\u0633\u0644\u00a0\u0627\u0644\u062f\u0646\u0627<\/a>. \u0627\u0644\u062d\u0630\u0641 \u0647\u0648 \u0641\u0642\u062f\u0627\u0646 \u0644\u0645\u0648\u0627\u062f \u0648\u0631\u0627\u062b\u064a\u0629. \u064a\u062a\u0631\u0627\u0648\u062d \u0639\u062f\u062f\u00a0\u0627\u0644\u0646\u0648\u0643\u0644\u064a\u0648\u062a\u064a\u062f\u0627\u062a<\/a>\u00a0\u0627\u0644\u062a\u064a \u064a\u0645\u0643\u0646 \u0623\u0646 \u062a\u062d\u0630\u0641 \u0645\u0646\u00a0\u0632\u0648\u062c \u00a0\u0642\u0627\u0639\u062f\u064a<\/a>\u00a0\u0648\u0627\u062d\u062f \u0625\u0644\u0649 \u062c\u0632\u0621 \u0643\u0627\u0645\u0644 \u0645\u0646 \u0627\u0644\u0643\u0631\u0648\u0645\u0648\u0633\u0648\u0645. \u0645\u0627 \u0642\u062f \u064a\u0633\u0628\u0628 \u0627\u0644\u062d\u0630\u0641 \u0647\u0648 \u0627\u0644\u0623\u062e\u0637\u0627\u0621 \u0627\u0644\u062a\u064a \u062a\u062d\u062f\u062b \u0641\u064a\u00a0\u0627\u0644\u062a\u0639\u0627\u0628\u0631 \u0627\u0644\u0635\u0628\u063a\u0648\u064a<\/a>\u00a0\u062e\u0644\u0627\u0644 \u0639\u0645\u0644\u064a\u0629\u00a0\u0627\u0644\u0627\u0646\u062a\u0635\u0627\u0641<\/a>. \u0648\u0647\u0630\u0627 \u064a\u0633\u0628\u0628 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646\u00a0\u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629<\/a> \u0627\u0644\u062e\u0637\u064a\u0631\u0629”. \u0645\u0642\u062a\u0628\u0633 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646:<\/p>\n

https:\/\/ar.wikipedia.org\/wiki\/\u062d\u0630\u0641_(\u0648\u0631\u0627\u062b\u0629)<\/a><\/p>\n

7-“\u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0633\u0631\u064a\u0631\u064a (\u0627\u0644\u0627\u0643\u0644\u064a\u0646\u064a\u0643\u064a): \u0648\u0647\u0648 \u0645\u0631\u0636 \u0644\u0647 \u0639\u0644\u0627\u0645\u0627\u062a \u0648\u0623\u0639\u0631\u0627\u0636 \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u0645\u064a\u0632\u0629 \u060c \u0648\u062a\u062e\u062a\u0644\u0641 \u0639\u0646 \u0627\u0644\u0645\u0631\u0636 \u0627\u0644\u0630\u064a \u0644\u0627 \u062a\u0638\u0647\u0631 \u0644\u0647 \u0623\u0639\u0631\u0627\u0636 (\u062f\u0648\u064a\u0646 \u0633\u0631\u064a\u0631\u064a)\u060c \u0627\u0644\u0630\u064a \u064a\u0641\u062a\u0642\u0631 \u0625\u0644\u0649 \u0639\u0644\u0627\u0645\u0627\u062a \u0648\u0623\u0639\u0631\u0627\u0636 \u064a\u0645\u0643\u0646 \u0627\u0643\u062a\u0634\u0627\u0641\u0647\u0627. \u0645\u0631\u0636 \u0627\u0644\u0633\u0643\u0631\u064a\u060c \u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644 \u060c \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0645\u0631\u0636\u064b\u0627 \u062f\u0648\u064a\u0646 \u0633\u0631\u064a\u0631\u064a \u0644\u0639\u062f\u0629 \u0633\u0646\u0648\u0627\u062a \u0642\u0628\u0644 \u0623\u0646 \u064a\u0635\u0628\u062d \u0645\u0631\u0636\u064b\u0627 \u0633\u0631\u064a\u0631\u064a\u064b\u0627”. \u062a\u0631\u062c\u0645\u0646\u0627\u0647 \u0645\u0646 \u0646\u0635 \u0648\u0631\u062f \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0639\u0646\u0648\u0627\u0646: https:\/\/www.medicinenet.com\/clinical_disease\/definition.htm<\/a><\/p>\n

\u0627\u0644\u0645\u0635\u062f\u0631:<\/strong><\/p>\n

https:\/\/microbiologysociety.org\/news\/press-releases\/one-year-of-sars-cov-2-evolution.html<\/em><\/a><\/p>\n

\"\"
\u0627\u0644\u0623\u0633\u062a\u0627\u0630 \u0639\u062f\u0646\u0627\u0646 \u0623\u062d\u0645\u062f \u0627\u0644\u062d\u0627\u062c\u064a<\/span><\/figcaption><\/figure>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

One year of SARS-CoV-2 evolution (\u062c\u0645\u0639\u064a\u0629 \u0639\u0644\u0645 \u0627\u0644\u0623\u062d\u064a\u0627\u0621 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 – Microbiology Society) \u0646\u0634\u0631 \u0628\u0627\u062d\u062b\u0648\u0646 \u0641\u064a 15 \u0623\u0628\u0631\u064a\u0644 2021 \u0645\u0631\u0627\u062c\u0639\u0629 \u0641\u0627\u062d\u0635\u0629 \u0648\u0634\u0627\u0645\u0644\u0629 \u0639\u0646 \u0637\u0641\u0631\u0627\u062a \u0641\u064a\u0631\u0648\u0633 \u0633\u0627\u0631\u0633-\u0643\u0648\u0641-2 \u0627\u0644\u062a\u064a \u062d\u062f\u062b\u062a \u062e\u0644\u0627\u0644 \u0627\u0644\u0639\u0627\u0645 \u0627\u0644\u0645\u0627\u0636\u064a (1) \u0641\u064a \u0645\u062c\u0644\u0629 \u0639\u0644\u0645 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u0627\u062a \u0627\u0644\u0639\u0627\u0645 (General Virology) (\u0627\u0646\u0638\u0631 2). \u00a0\u0647\u0630\u0627 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u062a\u0646\u0627\u0642\u0634 \u0646\u062a\u0627\u0626\u062c \u0623\u0643\u062b\u0631 \u0645\u0646 180 \u062f\u0631\u0627\u0633\u0629 \u0628\u062d\u062b\u064a\u0629 \u0646\u0634\u0631\u062a \u0633\u0627\u0628\u0642\u064b\u0627 \u0648\u062a\u062a\u0628\u0639 \u0627\u0644\u062a\u063a\u064a\u064a\u0631\u0627\u062a \u0627\u0644\u062a\u064a \u062d\u062f\u062b\u062a …<\/p>\n","protected":false},"author":4,"featured_media":10388,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[19],"tags":[],"class_list":["post-10384","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-19"],"_links":{"self":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/10384","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10384"}],"version-history":[{"count":4,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/10384\/revisions"}],"predecessor-version":[{"id":10392,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/posts\/10384\/revisions\/10392"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=\/wp\/v2\/media\/10388"}],"wp:attachment":[{"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10384"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10384"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.qatifscience.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10384"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}